ChemicalBook > CAS DataBase List > Ziprasidone mesilate
Ziprasidone mesilate
- Product Name
- Ziprasidone mesilate
- CAS No.
- 199191-69-0
- Chemical Name
- Ziprasidone mesilate
- Synonyms
- ZIPRASIDONE MESYLATE;ziprasidone mesilate;Ziprasidone mesilate Impurity;Ziprasidone (mesylate hydrate);Ziprasidone mesylate trihydrate;Ziprasidone mesilate trihydrate CRS;Ziprasidone Hcl / Mesilate 138982-67-9 /;5-[2-[4-(1,2-benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2h-indol-2-one mesilate;2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-,monomethanesulfonate, trihydrate;2H-INDOL-2-ONE, 5-[2-[4-(1,2-BENZISOTHIAZOL-3-YL)-1-PIPERAZINYL]ETHYL]-6-CHLORO-1,3-DIHYDRO-, MONOMETHANESULFONATE, TRIHYDRATE
- CBNumber
- CB6433336
- Molecular Formula
- C22H31ClN4O7S2
- Formula Weight
- 563.09
- MOL File
- 199191-69-0.mol
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Ziprasidone mesilate Property
- InChIKey
- WLQZEFFFIUHSJB-UHFFFAOYSA-N
- SMILES
- C1(N2CCN(CC2)CCC2=CC3CC(=O)NC=3C=C2Cl)C2C=CC=CC=2SN=1.S(C)(O)(=O)=O.O.O.O
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P314Get medical advice/attention if you feel unwell.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- Y0001626
- Product name
- Ziprasidone mesylate trihydrate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 30 mg
- Price
- $225
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- Y0001626
- Product name
- Ziprasidone mesylate trihydrate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0001626
- Price
- $220
- Updated
- 2024/03/01
American Custom Chemicals Corporation
- Product number
- HCH0036753
- Product name
- 5-(2-(4-(1,2-BENZISOTHIAZOL-3YL)-1-PIPERAZINYL)ETHYL)-6-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE MESILATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $909.56
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- BZ164581
- Product name
- Ziprasidone mesylate
- Packaging
- 50mg
- Price
- $262.5
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- BZ164581
- Product name
- Ziprasidone mesylate
- Packaging
- 10mg
- Price
- $75
- Updated
- 2021/12/16
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Ziprasidone mesilate Chemical Properties,Usage,Production
Uses
Antipsychotic (central D2and 5HT2receptor antagonist).
Definition
ChEBI: The methanesulfonate trihydrate salt of ziprasidone.
brand name
Geodon (Pfizer).
in vivo
Ziprasidone mesylate trihydrate (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold[3].
| Animal Model: | Eight-week-old female Sprague-Dawley rats weighing 200 to 250 g[3] |
| Dosage: | 20 mg/kg |
| Administration: | Oral gavage; 20 mg/kg; once daily; 7 weeks |
| Result: | Gained significantly less weight (P = 0.031), had a lower level of physical activity (P = 0.016), showed a higher resting energy expenditure (P < 0.001), and displayed a greater capacity for thermogenesis when subjected to cold (P < 0.001). |
IC 50
Rat 5-HT2 Receptor: 0.42 nM (Ki); Rat 5-HT1A Receptor: 3.4 nM (Ki); Rat D2 Receptor: 4.8 nM (Ki)
Ziprasidone mesilate Preparation Products And Raw materials
Raw materials
Preparation Products
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Ziprasidone mesilate Suppliers
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View Lastest Price from Ziprasidone mesilate manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Ziprasidone mesilate 199191-69-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10kg
- Release date
- 2023-01-05
Career Henan Chemical Co
- Product
- Ziprasidone mesilate 199191-69-0
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-09
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