ChemicalBook > CAS DataBase List > DL-O-Phosphoserine

DL-O-Phosphoserine

Product Name
DL-O-Phosphoserine
CAS No.
17885-08-4
Chemical Name
DL-O-Phosphoserine
Synonyms
DL-SOP;Serophen;NSC 90791;H-SER(P)-OH;Energoserina;PHOSPHOSERINE;H-DL-SER(P)-OH;H-SER(PO3H2)-OH;H-SER(H2PO3)-OH;L-PHOSPHOSERINE
CBNumber
CB6441658
Molecular Formula
C3H8NO6P
Formula Weight
185.07
MOL File
17885-08-4.mol
More
Less

DL-O-Phosphoserine Property

Melting point:
190 °C(lit.)
Boiling point:
475.4±55.0 °C(Predicted)
Density 
1.809
storage temp. 
-15°C
solubility 
H2O: 50 mg/mL hot, clear, colorless to slightly yellow
form 
Solid
pka
1.71±0.10(Predicted)
color 
White to Off-White
Merck 
7363
BRN 
1726828
InChI
InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
InChIKey
BZQFBWGGLXLEPQ-REOHCLBHSA-N
SMILES
C(O)(=O)[C@H](COP(O)(O)=O)N
CAS DataBase Reference
17885-08-4(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
F 
10
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
79710
Product name
O-Phospho-DL-serine
Purity
≥98.0% (NT)
Packaging
10g
Price
$117
Updated
2025/07/31
Sigma-Aldrich
Product number
79710
Product name
O-Phospho-DL-serine
Purity
≥98.0% (NT)
Packaging
50g
Price
$369
Updated
2025/07/31
TRC
Product number
P353763
Product name
O-Phospho-DL-serine
Packaging
5g
Price
$100
Updated
2021/12/16
Usbiological
Product number
287872
Product name
O-Phospho-DL-serine
Packaging
10g
Price
$202
Updated
2021/12/16
Chem-Impex
Product number
12026
Product name
O-Phospho-DL-serine,98%(Titration)
Purity
98%(Titration)
Packaging
1G
Price
$22.4
Updated
2021/12/16
More
Less

DL-O-Phosphoserine Chemical Properties,Usage,Production

Chemical Properties

White to faint beige crystalline powder

Uses

DL-O-Phosphoserine is used in alternative pathways for biosynthesis of cysteine and of selenocysteine.

Definition

ChEBI: A serine derivative that is serine substituted at the oxygen atom by a phosphono group.

Biochem/physiol Actions

O-Phospho-DL-serine (pSer) is used in the study of non-enzymatic aminophospholipid glycation.

in vivo

O-phospho-L-serin can be used in retinal research to explore the regulatory mechanism of Müller glial cell proliferation and photoreceptor regeneration; in bone repair research, to evaluate the effects on bone cement performance and bone healing; in insect research, to identify the role of D-serine in insect growth and development. In the zebrafish light-damaged retinal model experiment, O-phospho-L-serin (20 mM, 0.5 μL; iv; injected before light treatment; single dose) can significantly reduce the number of proliferating cell nuclear antigen (PCNA)-positive Müller glial cells 51 hours after light damage, and inhibit the regeneration of cones in the light-damaged retina, but has no significant effect on the number of light-induced photoreceptor cell death[1].
In a miniature pig mandibular bone defect model experiment, a modified bone cement prepared by surgical implantation of a mixture of O-phospho-L-serin (Biozement D (2 g)-collagen-I (2.5%)-phosphoserine (50 mg)) was administered. Compared with the unmodified bone cement, the treated group had a higher absorption rate and bone regeneration rate, which effectively promoted bone healing[2].
In a silkworm growth and development experiment, O-phospho-L-serin (20 mM, 1 mL; added to feed; daily administration, from first to fifth instar larvae) delayed the development of silkworm larvae by about 6 days, significantly reduced the survival rate of larvae, and reduced the D-serine level in larvae until the cocooning stage compared with the control group[3].

Animal Model:Zebrafish retinal light damage model[1]
Dosage:0.65% saline containing either 20 mM O-phospho-L-serine (L-SOP), 0.5 μL
Administration:Intravitreally injection via Hamilton syringe; single dose
Result:Decreased the number of PCNA-positive Müller glia 51 hours after light damage.
Inhibited the regeneration of cone photoreceptors in the light-damaged retina.
There was no significant difference in the number of light-induced photoreceptor cell deaths between the O-phospho-L-serin-injected group and the control group 24 hours after light treatment.

IC 50

Human Endogenous Metabolite

DL-O-Phosphoserine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DL-O-Phosphoserine Suppliers

China 88 Europe 2 Germany 2 India 3 Switzerland 4 United Kingdom 6 United States 17 Global 122
Shanghai Chiral Chemicals Inc.
Tel
021-37285021 13472570865
Fax
86-021-51714507
Email
tym7xi@aliyun.com
Country
China
ProdList
308
Advantage
64
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
sales@uhnshanghai.com
Country
China
ProdList
998
Advantage
58
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
More
Less

View Lastest Price from DL-O-Phosphoserine manufacturers

Wuhan Fortuna Chemical Co.,Ltd
Product
DL-O-Phosphoserine 17885-08-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20TONS
Release date
2025-07-30
WUHAN FORTUNA CHEMICAL CO., LTD
Product
DL-O-Phosphoserine 17885-08-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-04-07
Career Henan Chemical Co
Product
O-PHOSPHO-L-SERINE 17885-08-4
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-15

17885-08-4, DL-O-PhosphoserineRelated Search:

Fmoc-O-(benzylphospho)-L-serine Phosphatidylserine FMOC-SER(PO3H2)-OH Fmoc-O-(benzylphospho)-L-threonine O-Phospho-L-serine DL-O-Phosphoserine DL-Serine DOPS BOC-O-DIPHENYLPHOSPHO-L-SERINE O-PHOSPHO-D-SERINE DL-O-PHOSPHOSERINE, BARIUM SALT 1-PALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT O-PHOSPHO-L-THREONINE 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT) 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE, SODIUM SALT BOC-O-DIBENZYLPHOSPHO-L-SERINE N(ALPHA)-BOC-O-(DIMETHYLPHOSPHO)-L-THREO

  • DL-2-Amino-3-hydroxypropanoic acid 3-phosphate, DL-Serine monophosphoric acid, DL-SOP
  • Serophen
  • DL-O-Phosphorylserine
  • DL-O-Serine phosphate
  • Energoserina
  • NSC 90791
  • Serine, dihydrogen phosphate (ester) (9CI)
  • Serine, dihydrogen phosphate (ester), DL- (8CI)
  • (2S)-2-amino-3-phosphonooxy-propionic acid
  • 3-O-Phosphoserine
  • L-3-Phosphoserine
  • L-Serinephosphoric acid
  • L-Seryl phosphate
  • O-phosphono-L-serine
  • O-phosphonoserine
  • (S)-2-amino-3-hydroxypropanoic acid 3-phosphate
  • Serine, dihydrogen phosphate (ester), L- (8CI)
  • O-PHOSPHO-DL-SERINE >= 98.0% (NT)
  • DL-Ser(H2PO3)-OH
  • O-Phospho-DL-serine≥ 98% (Titration)
  • H-DL-SER(H2PO3)-OH
  • H-DL-SER(P)-OH
  • H-SER(PO3H2)-OH
  • H-SER(P)-OH
  • H-SER(H2PO3)-OH
  • DL-2-AMINO-3-HYDROXYPROPANOIC ACID 3-PHOSPHATE
  • DL-O-PHOSPHOSERINE
  • DL-SERINE MONOPHOSPHORIC ACID
  • DL-SOP
  • L-PHOSPHOSERINE
  • L-SERINE-O-PHOSPHATE
  • L-O-PHOSPHOSERINE
  • SERINE(PO3H2)-OH
  • O-PHOSPHO-DL-SERINE
  • O-PHOSPHORYL-DL-SERINE
  • O-PHOSPHORYL-L-SERINE
  • PHOSPHOSERINE
  • PHOSPHOSERINE ANTIBODY INHIBITOR
  • DL-Phosphoserine Anhydrous
  • DL-serine dihydrogen phosphate
  • DL-Phosphoserine
  • DL-Serine phosphate
  • TIMTEC-BB SBB000251
  • 2-amino-3-phosphonooxy-propanoic acid
  • Serine, O-phosphono-
  • erine, O-phosphono
  • DL-2-Amino-3-hydroxypropanoic acid 3-phosphate|||O-PHOSPHO-L-SERINE|||DL-SOP
  • DL-O-Phosphoserine, 10 mM in DMSO
  • O-Phospho-<sc>DL</sc>-serine
  • Serine(phospho)
  • 17885-08-4
  • C3H8NO6P
  • Modified Amino Acids
  • Metabolomics
  • Metabolic Libraries
  • I - Z
  • Biochemicals and Reagents
  • Amino Acids and Peptides