ChemicalBook > CAS DataBase List > DL-O-Phosphoserine

DL-O-Phosphoserine

Product Name: DL-O-Phosphoserine
CAS No.: 17885-08-4
Chemical Name: DL-O-Phosphoserine
Synonyms: DL-SOP;Serophen;NSC 90791;H-SER(P)-OH;Energoserina;PHOSPHOSERINE;H-DL-SER(P)-OH;H-SER(PO3H2)-OH;H-SER(H2PO3)-OH;L-PHOSPHOSERINE
CBNumber: CB6441658
Molecular Formula: C3H8NO6P
Formula Weight: 185.07
MOL File: 17885-08-4.mol

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DL-O-Phosphoserine Property

Melting point:: 190 °C(lit.)
Boiling point:: 475.4±55.0 °C(Predicted)
Density: 1.809
storage temp.: -15°C
solubility: H₂O: 50 mg/mL hot, clear, colorless to slightly yellow
form: Solid
pka: 1.71±0.10(Predicted)
color: White to Off-White
Merck: 7363
BRN: 1726828
InChI: InChI=1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
InChIKey: BZQFBWGGLXLEPQ-REOHCLBHSA-N
SMILES: C(O)(=O)[C@H](COP(O)(O)=O)N
CAS DataBase Reference: 17885-08-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 79710
Product name: O-Phospho-DL-serine
Purity: ≥98.0% (NT)
Packaging: 10g
Price: $117
Updated: 2025/07/31

Sigma-Aldrich

Product number: 79710
Product name: O-Phospho-DL-serine
Purity: ≥98.0% (NT)
Packaging: 50g
Price: $369
Updated: 2025/07/31

TRC

Product number: P353763
Product name: O-Phospho-DL-serine
Packaging: 5g
Price: $100
Updated: 2021/12/16

Usbiological

Product number: 287872
Product name: O-Phospho-DL-serine
Packaging: 10g
Price: $202
Updated: 2021/12/16

Chem-Impex

Product number: 12026
Product name: O-Phospho-DL-serine,98%(Titration)
Purity: 98%(Titration)
Packaging: 1G
Price: $22.4
Updated: 2021/12/16

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DL-O-Phosphoserine Chemical Properties,Usage,Production

Chemical Properties

White to faint beige crystalline powder

Uses

DL-O-Phosphoserine is used in alternative pathways for biosynthesis of cysteine and of selenocysteine.

Definition

ChEBI: A serine derivative that is serine substituted at the oxygen atom by a phosphono group.

Biochem/physiol Actions

O-Phospho-DL-serine (pSer) is used in the study of non-enzymatic aminophospholipid glycation.

in vivo

O-phospho-L-serin can be used in retinal research to explore the regulatory mechanism of Müller glial cell proliferation and photoreceptor regeneration; in bone repair research, to evaluate the effects on bone cement performance and bone healing; in insect research, to identify the role of D-serine in insect growth and development. In the zebrafish light-damaged retinal model experiment, O-phospho-L-serin (20 mM, 0.5 μL; iv; injected before light treatment; single dose) can significantly reduce the number of proliferating cell nuclear antigen (PCNA)-positive Müller glial cells 51 hours after light damage, and inhibit the regeneration of cones in the light-damaged retina, but has no significant effect on the number of light-induced photoreceptor cell death^[1].
In a miniature pig mandibular bone defect model experiment, a modified bone cement prepared by surgical implantation of a mixture of O-phospho-L-serin (Biozement D (2 g)-collagen-I (2.5%)-phosphoserine (50 mg)) was administered. Compared with the unmodified bone cement, the treated group had a higher absorption rate and bone regeneration rate, which effectively promoted bone healing^[2].
In a silkworm growth and development experiment, O-phospho-L-serin (20 mM, 1 mL; added to feed; daily administration, from first to fifth instar larvae) delayed the development of silkworm larvae by about 6 days, significantly reduced the survival rate of larvae, and reduced the D-serine level in larvae until the cocooning stage compared with the control group^[3].

Animal Model:	Zebrafish retinal light damage model^[1]
Dosage:	0.65% saline containing either 20 mM O-phospho-L-serine (L-SOP), 0.5 μL
Administration:	Intravitreally injection via Hamilton syringe; single dose
Result:	Decreased the number of PCNA-positive Müller glia 51 hours after light damage. Inhibited the regeneration of cone photoreceptors in the light-damaged retina. There was no significant difference in the number of light-induced photoreceptor cell deaths between the O-phospho-L-serin-injected group and the control group 24 hours after light treatment.

IC 50

Human Endogenous Metabolite

DL-O-Phosphoserine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DL-O-Phosphoserine manufacturers

Wuhan Fortuna Chemical Co.,Ltd

Product: DL-O-Phosphoserine 17885-08-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 20TONS
Release date: 2025-07-30

WUHAN FORTUNA CHEMICAL CO., LTD

Product: DL-O-Phosphoserine 17885-08-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-04-07

Career Henan Chemical Co

Product: O-PHOSPHO-L-SERINE 17885-08-4
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

17885-08-4, DL-O-PhosphoserineRelated Search:

Fmoc-O-(benzylphospho)-L-serine Phosphatidylserine FMOC-SER(PO3H2)-OH Fmoc-O-(benzylphospho)-L-threonine O-Phospho-L-serine DL-O-Phosphoserine DL-Serine DOPS BOC-O-DIPHENYLPHOSPHO-L-SERINE O-PHOSPHO-D-SERINE DL-O-PHOSPHOSERINE, BARIUM SALT 1-PALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT O-PHOSPHO-L-THREONINE 1-STEAROYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT) 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE, SODIUM SALT BOC-O-DIBENZYLPHOSPHO-L-SERINE N(ALPHA)-BOC-O-(DIMETHYLPHOSPHO)-L-THREO

DL-2-Amino-3-hydroxypropanoic acid 3-phosphate, DL-Serine monophosphoric acid, DL-SOP

Serophen

DL-O-Phosphorylserine

DL-O-Serine phosphate

Energoserina

NSC 90791

Serine, dihydrogen phosphate (ester) (9CI)

Serine, dihydrogen phosphate (ester), DL- (8CI)

(2S)-2-amino-3-phosphonooxy-propionic acid

3-O-Phosphoserine

L-3-Phosphoserine

L-Serinephosphoric acid

L-Seryl phosphate

O-phosphono-L-serine

O-phosphonoserine

(S)-2-amino-3-hydroxypropanoic acid 3-phosphate

Serine, dihydrogen phosphate (ester), L- (8CI)

O-PHOSPHO-DL-SERINE >= 98.0% (NT)

DL-Ser(H2PO3)-OH

O-Phospho-DL-serine≥ 98% (Titration)

H-DL-SER(H2PO3)-OH

H-DL-SER(P)-OH

H-SER(PO3H2)-OH

H-SER(P)-OH

H-SER(H2PO3)-OH

DL-2-AMINO-3-HYDROXYPROPANOIC ACID 3-PHOSPHATE

DL-O-PHOSPHOSERINE

DL-SERINE MONOPHOSPHORIC ACID

DL-SOP

L-PHOSPHOSERINE

L-SERINE-O-PHOSPHATE

L-O-PHOSPHOSERINE

SERINE(PO3H2)-OH

O-PHOSPHO-DL-SERINE

O-PHOSPHORYL-DL-SERINE

O-PHOSPHORYL-L-SERINE

PHOSPHOSERINE

PHOSPHOSERINE ANTIBODY INHIBITOR

DL-Phosphoserine Anhydrous

DL-serine dihydrogen phosphate

DL-Phosphoserine

DL-Serine phosphate

TIMTEC-BB SBB000251

2-amino-3-phosphonooxy-propanoic acid

Serine, O-phosphono-

erine, O-phosphono

DL-2-Amino-3-hydroxypropanoic acid 3-phosphate|||O-PHOSPHO-L-SERINE|||DL-SOP

DL-O-Phosphoserine, 10 mM in DMSO

O-Phospho-<sc>DL</sc>-serine

Serine(phospho)

17885-08-4

C3H8NO6P

Modified Amino Acids

Metabolomics

Metabolic Libraries

I - Z

Biochemicals and Reagents

Amino Acids and Peptides