ChemicalBook > CAS DataBase List > 2-(2-Chlorophenyl)acetonitrile

2-(2-Chlorophenyl)acetonitrile

Product Name
2-(2-Chlorophenyl)acetonitrile
CAS No.
2856-63-5
Chemical Name
2-(2-Chlorophenyl)acetonitrile
Synonyms
O-CHLOROBENZYL CYANIDE;2-Cyanobenzyl chloride;2-CHLOROPHENYLACETONITRILE;OCCN;2-Chlorobenzyl;2-Chlorobenzyl cyani;Dopamine Impurity 36;2-CHLOROBENZYL CYANIDE;Oxiconazole Impurity 10;0-Chloro benzoy cyanidel
CBNumber
CB6447034
Molecular Formula
C8H6ClN
Formula Weight
151.59
MOL File
2856-63-5.mol
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2-(2-Chlorophenyl)acetonitrile Property

Melting point:
24 °C (lit.)
Boiling point:
240-242 °C (lit.)
Density 
1
refractive index 
1.5425-1.5445
Flash point:
>110°C
storage temp. 
Sealed in dry,Room Temperature
Water Solubility 
Insoluble in water
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
powder to lump to clear liquid
color 
White or Colorless to Light yellow
FreezingPoint 
22.0 to 25.0 ℃
BRN 
2043683
Exposure limits
NIOSH: IDLH 25 mg/m3
CAS DataBase Reference
2856-63-5(CAS DataBase Reference)
NIST Chemistry Reference
2-Chlorobenzyl cyanide(2856-63-5)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
36/37/38-23/24/25
Safety Statements 
45-36/37/39-28B-26-22
RIDADR 
3276
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269095
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H300Fatal if swallowed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309IF exposed or if you feel unwell:

P310Immediately call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
188492
Product name
2-Chlorobenzyl cyanide
Purity
97%
Packaging
5g
Price
$50.1
Updated
2023/01/07
TCI Chemical
Product number
C1125
Product name
2-Chlorobenzyl Cyanide
Purity
>98.0%(GC)
Packaging
25g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
C1125
Product name
2-Chlorobenzyl Cyanide
Purity
>98.0%(GC)
Packaging
500g
Price
$261
Updated
2025/07/31
TRC
Product number
C364465
Product name
2-Chlorobenzyl Cyanide
Packaging
10g
Price
$150
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK552561
Product name
2-Chlorobenzyl Cyanide
Purity
99%
Packaging
250g
Price
$192
Updated
2021/12/16
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2-(2-Chlorophenyl)acetonitrile Chemical Properties,Usage,Production

Chemical Properties

CLEAR SLIGHTLY YELLOW LIQUID AFTER MELTING

Uses

2-Chlorobenzyl cyanide was used in the synthesis of clopidogrel, platelet aggregation inhibitor.

Synthesis

1058649-12-9

10442-39-4

2856-63-5

GENERAL METHODS: A mixture of MOM-ether (1 mmol) and tetrabutylammonium cyanide (2 mmol) was added to [Hmim][NO3] (0.4 mmol) and the reaction was carried out under microwave irradiation (the reaction temperature was maintained at 135 °C and the power at 170 W). The reaction process was monitored by thin-layer chromatography (TLC) and the eluent was hexane/ethyl acetate (5:1). After completion of the reaction, the mixture was extracted with ether (3 × 10 mL). The organic phases were combined and dried with anhydrous Na2SO4, followed by rotary evaporation to remove the solvent to give the crude product. The crude product was purified by neutral alumina column chromatography with hexane/ethyl acetate (5:1, 75 mL) as the eluent to give high purity o-chlorophenylacetonitrile, the spectral data of which were in agreement with those reported in the literature.

References

[1] Tetrahedron Letters, 2010, vol. 51, # 25, p. 3274 - 3276
[2] Tetrahedron Letters, 2014, vol. 55, # 32, p. 4424 - 4426

2-(2-Chlorophenyl)acetonitrile Preparation Products And Raw materials

Raw materials

2-Nitrophenylacetonitrile

Preparation Products

Chlorphoxim 2-Chlorophenylacetic acid Methyl 2-chlorophenylacetate 2-(2-CHLORO-PHENYL)-ETHANESULFONYL CHLORIDE METHYL ALPHA-BROMO-2-CHLOROPHENYLACETATE Bupropion
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View Lastest Price from 2-(2-Chlorophenyl)acetonitrile manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-(2-Chlorophenyl)acetonitrile 2856-63-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10000KGS
Release date
2025-11-14
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chlorobenzyl cyanide 2856-63-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chlorobenzyl cyanide 2856-63-5
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
600 tons
Release date
2020-04-24

2856-63-5, 2-(2-Chlorophenyl)acetonitrileRelated Search:

Calcium chloride Mepiquat chloride Acetonitrile Choline chloride 2-Chlorobenzoic acid Benzyl chloride Ammonium chloride Polyvinyl chloride 2-Chlorobenzaldehyde Sodium chloride 2-Chlorophenylacetic acid 2-Chlorophenol 2,4-Dichlorophenylacetonitrile 2-CHLORO-6-FLUOROPHENYLACETONITRILE Glycolonitrile 2-(4-Amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile 2,6-Dichlorobenzyl acetonitrile 2-Chlorophenyl cyclopentyl ketone

  • 2-Chlorobenzeneacetonitrile
  • Acetonitrile, (o-chlorophenyl)-
  • Benzeneacetonitrile, 2-chloro-
  • OCCN
  • O-CHLOROBENZYL CYANIDE
  • (O-CHLOROPHENYL)ACETONITRILE
  • 2-CHLOROBENZYL CYANIDE
  • 2-CHLOROPHENYLACETONITRILE
  • 2-Chlorophenylacetonitrile, 97+%
  • 2-Chlorobenzyl
  • 0-Chloro benzoy cyanidel
  • 2-Chlorobenzyl cyanide 97%
  • 2-Chlorobenzyl cyanide,97%
  • 2-Chlorophenylacetonitrilel
  • 2-Cyanobenzyl chloride
  • 9) ORTHO CHLORO BENZYL CYANIDE
  • 2-Chlorophenylacetonitrile, 98+%
  • 2-Cchlorophenylacetonitrile
  • 2-Chlorobenzyl cyani
  • 2-Chlorophenylacetonitrile 97%
  • Acetonitrile, (o-chlorophenyl)- (8CI)
  • Benzeneacetonitrile, 2-chloro- (9CI)
  • 2-(2-chlorophenyl)ethanenitrile
  • 2-ChlorobenzylCyanide&gt
  • 2-CHLOROBENZYL CYANIDE 2856-63-5
  • 2-Chlorobenzyl cyanide ISO 9001：2015 REACH
  • Oxiconazole Impurity 10
  • 2-(2-chlorophenyl)acetonitrile
  • Dopamine Impurity 36
  • 2856-63-5
  • 2856-63-6
  • ARYL ISOCYANATE
  • Building Blocks
  • C8 to C9
  • Organic Building Blocks
  • Nitrogen Compounds
  • Cyanides/Nitriles
  • Aromatic Nitriles