ChemicalBook > CAS DataBase List > 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

Product Name: 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
CAS No.: 104253-44-3
Chemical Name: 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
Synonyms: RARECHEM AL BF 0717;METHYL 2-CHLORO-4-HYDROXYBENZOATE;2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER;Benzoic acid, 2-chloro-4-hydroxy-, methyl ester;2-Chloro-4-hydroxy-benzoic acid methyl ester≥ 99% (GC)
CBNumber: CB6452966
Molecular Formula: C8H7ClO3
Formula Weight: 186.59
MOL File: 104253-44-3.mol

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2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Property

Boiling point:: 298.3±20.0 °C(Predicted)
Density: 1.354±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 7.39±0.18(Predicted)
Appearance: Light yellow to brown Solid

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Safety

HS Code: 2918290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M340458
Product name: Methyl2-Chloro-4-hydroxybenzoate
Packaging: 500mg
Price: $175
Updated: 2021/12/16

Matrix Scientific

Product number: 119052
Product name: Methyl 2-chloro-4-hydroxybenzoate
Purity: 95+%
Packaging: 1g
Price: $324
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC70262
Product name: 2-Chloro-4-hydroxybenzoic acid methyl ester
Packaging: 2g
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: OR913032
Product name: 2-Chloro-4-hydroxy-benzoic acid methyl ester
Purity: 98%
Packaging: 1g
Price: $94
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC70262
Product name: 2-Chloro-4-hydroxybenzoic acid methyl ester
Packaging: 5G
Price: $100
Updated: 2021/12/16

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2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Tan crystalline powder

Synthesis

67-56-1

56363-84-9

104253-44-3

General procedure for the synthesis of methyl 2-chloro-4-hydroxybenzoate from methanol and 2-chloro-4-hydroxybenzoic acid: sulfoxide chloride (SOCl2, 1.5 mL) was slowly added to a solution of methanol (10 mL) containing 2-chloro-4-hydroxybenzoic acid (5 g, 0.03 mol). The reaction mixture was gradually heated from room temperature to reflux temperature and reacted under reflux conditions for 12 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford the target product methyl 2-chloro-4-hydroxybenzoate (Compound 132A, red solid, 5.4 g, 100% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 10.71 (s, 1H), 7.84-7.71 (m, 1H), 6.91 (d, J = 2.4 Hz, 1H), 6.82 (dd, J = 2.4, 8.7 Hz, 1H), 3.79 (s, 3H).

References

[1] Patent: EP3293177, 2018, A1. Location in patent: Paragraph 0332; 0333
[2] Patent: EP1764360, 2007, A1. Location in patent: Page/Page column 176-177
[3] Patent: WO2017/84629, 2017, A1. Location in patent: Paragraph 00316
[4] Patent: WO2017/84630, 2017, A1. Location in patent: Paragraph 00648
[5] Patent: WO2008/157330, 2008, A1. Location in patent: Page/Page column 87

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER manufacturers

Career Henan Chemica Co

Product: 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER 104253-44-3
Price: US $9.20/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2020-10-27

104253-44-3, 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTERRelated Search:

2-Chloro-4-hydroxybenzoic acid METHYL 2-CHLORO-4-METHOXYBENZOATE 2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER METHYL 2-CHLORO-3,4-DIMETHOXYBENZOATE 4-PENTYLPHENYL 2-CHLORO-4-(4-PENTYLBENZOYLOXY)BENZOATE 4-CHLORO-3-HYDROXY-BENZOIC ACID METHYL ESTER ETHYL 2-CHLORO-3,4-DIMETHOXYBENZOATE 4-OCTYLPHENYL 2-CHLORO-4-(4-HEPTYLBENZOYL-OXY)BENZOATE RARECHEM AL BF 0917 RARECHEM AL BI 0717 RARECHEM AL BI 1492 RARECHEM AL BI 0917 RARECHEM AL BF 0907 RARECHEM AL BI 0997 ethyl 2-chloro-4,6-dimethoxybenzoate RARECHEM AL BI 0907 RARECHEM AL BF 1492

METHYL 2-CHLORO-4-HYDROXYBENZOATE

2-CHLORO-4-HYDROXY-BENZOIC ACID METHYL ESTER

RARECHEM AL BF 0717

2-Chloro-4-hydroxy-benzoic acid methyl ester≥ 99% (GC)

Benzoic acid, 2-chloro-4-hydroxy-, methyl ester

104253-44-3

Aromatic Esters

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