1,2-BIS(4-PYRIDYL)ETHANE

Product Name: 1,2-BIS(4-PYRIDYL)ETHANE
CAS No.: 4916-57-8
Chemical Name: 1,2-BIS(4-PYRIDYL)ETHANE
Synonyms: SKL332;DK7423;NSC 11477;4,4'-ETHYLENEDIPYRIDINE;4,4'-Ethylenebispyridine;1,2-BIS(4-PYRIDYL)ETHANE;1,2-DI-(4-PYRIDYL) ETHANE;1,2-bis(4'-pyridyl)ethane;1,2-di(pyridin-4-yl)ethane;4,4'-Ethylenebis(pyridine)
CBNumber: CB6456414
Molecular Formula: C12H12N2
Formula Weight: 184.24
MOL File: 4916-57-8.mol

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1,2-BIS(4-PYRIDYL)ETHANE Property

Melting point:: 110-112 °C (lit.)
Boiling point:: 174 °C / 3mmHg
Density: 1.1160 (rough estimate)
refractive index: 1.6266 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
pka: 6.13±0.10(Predicted)
form: Crystals or Crystalline Powder
color: White to light yellow or pinkish
InChI: InChI=1S/C12H12N2/c1(11-3-7-13-8-4-11)2-12-5-9-14-10-6-12/h3-10H,1-2H2
InChIKey: DQRKTVIJNCVZAX-UHFFFAOYSA-N
SMILES: C(C1C=CN=CC=1)CC1C=CN=CC=1

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B51801
Product name: 1,2-Bis(4-pyridyl)ethane
Purity: 99%
Packaging: 1g
Price: $64.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: B51801
Product name: 1,2-Bis(4-pyridyl)ethane
Purity: 99%
Packaging: 10g
Price: $224
Updated: 2025/07/31

TCI Chemical

Product number: D3752
Product name: 1,2-Di(4-pyridyl)ethane
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: D3752
Product name: 1,2-Di(4-pyridyl)ethane
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $109
Updated: 2025/07/31

TRC

Product number: B525705
Product name: 1,2-Bis(4-pyridyl)ethane
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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1,2-BIS(4-PYRIDYL)ETHANE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystals or cryst. powder

Uses

1,2-Bis(4-pyridyl)ethane has been used as a flexible bridging ligand in the synthesis of metal-organic frameworks.

General Description

1,2-Bis(4-pyridyl)ethane is an N-donor ligand mainly used in the formation of molecular and coordination polymers with metal ions.

Synthesis

108-89-4

4916-57-8

5421-79-4

General procedure for the synthesis of 1,2-bis(4-pyridyl)ethane and tirofiban impurity 90 from 4-methylpyridine: 4-methylpyridine (1.6 g, 17.18 mmol), powdered sulfur (275 mg, 8.59 mmol), and concentrated hydrochloric acid (12 M, 0.48 mL, 5.76 mmol) were mixed, heated to 120 °C and stirred for 24 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted by adding dichloromethane (20 mL) and water. The organic phase was separated and purified by column chromatography (eluent: ethyl acetate/ethylamine = 97/2/1 to 90/7/3) to afford yellow solid 1,2-bis(4-pyridyl)ethane (520 mg, yield: 16%) and 4',4''-(propane-1,2,3-triyl)tripyridine (1.2 g, yield: 25%).

References

[1] Organic Letters, 2013, vol. 15, # 16, p. 4218 - 4221
[2] Patent: CN108440393, 2018, A. Location in patent: Paragraph 0055; 0058; 0059; 0060; 0061

1,2-BIS(4-PYRIDYL)ETHANE Preparation Products And Raw materials

Raw materials

Benzoyl peroxide 4-Methylpyridine Sodium sulfate Sodium chloride Sodium sulfite Cyclohexane Diisopropylamine 1,2-Dibromoethane Tetrahydrofuran Diethyl ether Dichloromethane n-Butyllithium Sodium carbonate

Preparation Products

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1,2-BIS(4-PYRIDYL)ETHANE Suppliers

Americas 1 Belgium 1 China 114 Europe 1 Germany 1 India 4 Japan 3 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 3 United States 13 Global 145

Nanjing Habo Medical Technology Co., Ltd.

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J & K SCIENTIFIC LTD.

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Beijing innoChem Science & Technology Co.,Ltd.

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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View Lastest Price from 1,2-BIS(4-PYRIDYL)ETHANE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1,2-Di(4-pyridyl)ethane 4916-57-8
Price: US $2.00-5.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons
Release date: 2025-07-09

Henan Aochuang Chemical Co.,Ltd.

Product: 1,2-BIS(4-PYRIDYL)ETHANE 4916-57-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-17

Dideu Industries Group Limited

Product: 1,2-BIS(4-PYRIDYL)ETHANE 4916-57-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-28

4916-57-8, 1,2-BIS(4-PYRIDYL)ETHANERelated Search:

2-Hydrazinopyridine 2-Cyanopyridine ETHANE MESO-1,2-BIS(4-PYRIDYL)-1,2-ETHANEDIOL TRIHYDRATE 1,2-Bis(dipropylacetamido)-1,2-di-4-pyridylethane 2,3-BIS(4-PYRIDYL)BUTANE 1,2-Bis(4-(4-methylsulfonyl)benzamido)-1,2-di-4-pyridylethane 2,3-DI(4-PYRIDYL)-2,3-BUTANEDIOL MESO-ALPHA,BETA-DI(4-PYRIDYL) GLYCOL Tolpadol 1 2-DI-(4-PYRIDYL)-1 2-ETHANEDIOL N,N'-(1,2-Di-4-pyridinyl-1,2-ethanediyl)bis-(1,1'-biphenyl)-4-carboxamide 1,2-BIS(4-PYRIDYL)ETHANE

4,4'-ETHYLENEDIPYRIDINE

1,2-DI-(4-PYRIDYL) ETHANE

1,2-BIS(4-PYRIDYL)ETHANE

1,2-Bis(4-pyridyl)ethane (BPA)

4,4'-Ethylenebis(pyridine)

4,4'-Ethylenebispyridine

1,2-Bis(4-pyridyl)ethane,97%

1,2-Bis(4-pyridyl)ethane,4,4′-Ethylenedipyridine

1,2-Bis(4-pyridyl)ethane ,96%

1,2-Bis(4-pyridyl)ethane, 97% 1GR

1,2-di(pyridin-4-yl)ethane

1,2-Bis-(4-pyridyl)ethane, GC 97%

1,2-Bis(4-pyridyl)ethane 99%

NSC 11477

Pyridine,4,4'-(1,2-ethanediyl)bis-

4-(2-pyridin-4-ylethyl)pyridine

1,2-Di(4-pyridyl)ethane&gt

1,2-BIS(4-PYRIDYL)ETHANE ISO 9001：2015 REACH

SKL332

DK7423

1,2-bis(4'-pyridyl)ethane

Dichloro-[1,3-bis(dlisopropylphenyl)imidazoliden-2-

4916-57-8

C9 to C46

Building Blocks

Pyridines

Heterocyclic Building Blocks

Heterocyclic Compounds