ChemicalBook > CAS DataBase List > 1,2-BIS(4-PYRIDYL)ETHANE

1,2-BIS(4-PYRIDYL)ETHANE

Product Name
1,2-BIS(4-PYRIDYL)ETHANE
CAS No.
4916-57-8
Chemical Name
1,2-BIS(4-PYRIDYL)ETHANE
Synonyms
SKL332;DK7423;NSC 11477;4,4'-ETHYLENEDIPYRIDINE;4,4'-Ethylenebispyridine;1,2-BIS(4-PYRIDYL)ETHANE;1,2-DI-(4-PYRIDYL) ETHANE;1,2-bis(4'-pyridyl)ethane;1,2-di(pyridin-4-yl)ethane;4,4'-Ethylenebis(pyridine)
CBNumber
CB6456414
Molecular Formula
C12H12N2
Formula Weight
184.24
MOL File
4916-57-8.mol
More
Less

1,2-BIS(4-PYRIDYL)ETHANE Property

Melting point:
110-112 °C (lit.)
Boiling point:
174 °C / 3mmHg
Density 
1.1160 (rough estimate)
refractive index 
1.6266 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
pka
6.13±0.10(Predicted)
form 
Crystals or Crystalline Powder
color 
White to light yellow or pinkish
InChI
InChI=1S/C12H12N2/c1(11-3-7-13-8-4-11)2-12-5-9-14-10-6-12/h3-10H,1-2H2
InChIKey
DQRKTVIJNCVZAX-UHFFFAOYSA-N
SMILES
C(C1C=CN=CC=1)CC1C=CN=CC=1
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B51801
Product name
1,2-Bis(4-pyridyl)ethane
Purity
99%
Packaging
1g
Price
$64.3
Updated
2025/07/31
Sigma-Aldrich
Product number
B51801
Product name
1,2-Bis(4-pyridyl)ethane
Purity
99%
Packaging
10g
Price
$224
Updated
2025/07/31
TCI Chemical
Product number
D3752
Product name
1,2-Di(4-pyridyl)ethane
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$44
Updated
2025/07/31
TCI Chemical
Product number
D3752
Product name
1,2-Di(4-pyridyl)ethane
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$109
Updated
2025/07/31
TRC
Product number
B525705
Product name
1,2-Bis(4-pyridyl)ethane
Packaging
100mg
Price
$60
Updated
2021/12/16
More
Less

1,2-BIS(4-PYRIDYL)ETHANE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystals or cryst. powder

Uses

1,2-Bis(4-pyridyl)ethane has been used as a flexible bridging ligand in the synthesis of metal-organic frameworks.

General Description

1,2-Bis(4-pyridyl)ethane is an N-donor ligand mainly used in the formation of molecular and coordination polymers with metal ions.

Synthesis

108-89-4

4916-57-8

5421-79-4

General procedure for the synthesis of 1,2-bis(4-pyridyl)ethane and tirofiban impurity 90 from 4-methylpyridine: 4-methylpyridine (1.6 g, 17.18 mmol), powdered sulfur (275 mg, 8.59 mmol), and concentrated hydrochloric acid (12 M, 0.48 mL, 5.76 mmol) were mixed, heated to 120 °C and stirred for 24 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted by adding dichloromethane (20 mL) and water. The organic phase was separated and purified by column chromatography (eluent: ethyl acetate/ethylamine = 97/2/1 to 90/7/3) to afford yellow solid 1,2-bis(4-pyridyl)ethane (520 mg, yield: 16%) and 4',4''-(propane-1,2,3-triyl)tripyridine (1.2 g, yield: 25%).

References

[1] Organic Letters, 2013, vol. 15, # 16, p. 4218 - 4221
[2] Patent: CN108440393, 2018, A. Location in patent: Paragraph 0055; 0058; 0059; 0060; 0061

1,2-BIS(4-PYRIDYL)ETHANE Preparation Products And Raw materials

Raw materials

Benzoyl peroxide 4-Methylpyridine Sodium sulfate Sodium chloride Sodium sulfite Cyclohexane Diisopropylamine 1,2-Dibromoethane Tetrahydrofuran Diethyl ether Dichloromethane n-Butyllithium Sodium carbonate

Preparation Products

More
Less

1,2-BIS(4-PYRIDYL)ETHANE Suppliers

Americas 1 Belgium 1 China 114 Europe 1 Germany 1 India 4 Japan 3 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 3 United States 13 Global 145
MDP ChemControl Ltd.
Tel
--
Fax
--
Email
chemcontrol@nextra.sk
Country
Slovakia
ProdList
6700
Advantage
60
More
Less

View Lastest Price from 1,2-BIS(4-PYRIDYL)ETHANE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1,2-Di(4-pyridyl)ethane 4916-57-8
Price
US $2.00-5.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons
Release date
2025-07-09
Henan Aochuang Chemical Co.,Ltd.
Product
1,2-BIS(4-PYRIDYL)ETHANE 4916-57-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-17
Dideu Industries Group Limited
Product
1,2-BIS(4-PYRIDYL)ETHANE 4916-57-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-28

4916-57-8, 1,2-BIS(4-PYRIDYL)ETHANERelated Search:

2-Hydrazinopyridine 2-Cyanopyridine ETHANE MESO-1,2-BIS(4-PYRIDYL)-1,2-ETHANEDIOL TRIHYDRATE 1,2-Bis(dipropylacetamido)-1,2-di-4-pyridylethane 2,3-BIS(4-PYRIDYL)BUTANE 1,2-Bis(4-(4-methylsulfonyl)benzamido)-1,2-di-4-pyridylethane 2,3-DI(4-PYRIDYL)-2,3-BUTANEDIOL MESO-ALPHA,BETA-DI(4-PYRIDYL) GLYCOL Tolpadol 1 2-DI-(4-PYRIDYL)-1 2-ETHANEDIOL N,N'-(1,2-Di-4-pyridinyl-1,2-ethanediyl)bis-(1,1'-biphenyl)-4-carboxamide 1,2-BIS(4-PYRIDYL)ETHANE

  • 4,4'-ETHYLENEDIPYRIDINE
  • 1,2-DI-(4-PYRIDYL) ETHANE
  • 1,2-BIS(4-PYRIDYL)ETHANE
  • 1,2-Bis(4-pyridyl)ethane (BPA)
  • 4,4'-Ethylenebis(pyridine)
  • 4,4'-Ethylenebispyridine
  • 1,2-Bis(4-pyridyl)ethane,97%
  • 1,2-Bis(4-pyridyl)ethane,4,4′-Ethylenedipyridine
  • 1,2-Bis(4-pyridyl)ethane ,96%
  • 1,2-Bis(4-pyridyl)ethane, 97% 1GR
  • 1,2-di(pyridin-4-yl)ethane
  • 1,2-Bis-(4-pyridyl)ethane, GC 97%
  • 1,2-Bis(4-pyridyl)ethane 99%
  • NSC 11477
  • Pyridine,4,4'-(1,2-ethanediyl)bis-
  • 4-(2-pyridin-4-ylethyl)pyridine
  • 1,2-Di(4-pyridyl)ethane&gt
  • 1,2-BIS(4-PYRIDYL)ETHANE ISO 9001：2015 REACH
  • SKL332
  • DK7423
  • 1,2-bis(4'-pyridyl)ethane
  • Dichloro-[1,3-bis(dlisopropylphenyl)imidazoliden-2-
  • 4916-57-8
  • C9 to C46
  • Building Blocks
  • Pyridines
  • Heterocyclic Building Blocks
  • Heterocyclic Compounds