4-Acetylbenzonitrile

Product Name: 4-Acetylbenzonitrile
CAS No.: 1443-80-7
Chemical Name: 4-Acetylbenzonitrile
Synonyms: 4-CYANOACETOPHENONE;p-Cyanacetophenon;4-AcetyL;AKOS 90467;P-CYANOACETOPHENONE;4-Cyano acetopheone;4-ACETYLBENZONITRILE;P-ACETYLBENZONITRILE;4'-caynoacetophenone;4'-Cyanoacetophenone
CBNumber: CB6464660
Molecular Formula: C9H7NO
Formula Weight: 145.16
MOL File: 1443-80-7.mol

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4-Acetylbenzonitrile Property

Melting point:: 56-59 °C(lit.)
Boiling point:: 95-96°C 14mm
Density: 1.1555 (rough estimate)
vapor pressure: 0.856Pa at 25℃
refractive index: 1.4500 (estimate)
Flash point:: 95-96°C/14mm
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform
form: Crystalline Mass or Crystalline Powder and Chunks
color: Light yellow to yellow-beige
Water Solubility: Soluble in chloroform. Insoluble in water.
BRN: 1932887
InChI: InChI=1S/C9H7NO/c1-7(11)9-4-2-8(6-10)3-5-9/h2-5H,1H3
InChIKey: NLPHXWGWBKZSJC-UHFFFAOYSA-N
SMILES: C(#N)C1=CC=C(C(C)=O)C=C1
LogP: 1.531 at 25℃
CAS DataBase Reference: 1443-80-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-20/21/22
Safety Statements: 36-36/37/39-26-22
RIDADR: 3276
WGK Germany: 3
Hazard Note: Harmful/Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29269090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 154393
Product name: 4-Acetylbenzonitrile
Purity: 99%
Packaging: 5g
Price: $141
Updated: 2025/07/31

Sigma-Aldrich

Product number: 154393
Product name: 4-Acetylbenzonitrile
Purity: 99%
Packaging: 25g
Price: $432.6
Updated: 2025/07/31

TCI Chemical

Product number: C1141
Product name: 4'-Cyanoacetophenone
Purity: >97.0%(GC)
Packaging: 10g
Price: $30
Updated: 2025/07/31

TCI Chemical

Product number: C1141
Product name: 4'-Cyanoacetophenone
Purity: >97.0%(GC)
Packaging: 25g
Price: $51
Updated: 2025/07/31

TRC

Product number: C987505
Product name: p-Cyanoacetophenone
Packaging: 1g
Price: $85
Updated: 2021/12/16

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4-Acetylbenzonitrile Chemical Properties,Usage,Production

Chemical Properties

light yellow to yellow-beige crystalline mass or crystalline powder and chunks

Uses

4-Acetylbenzonitrile is used in the preparation of antimalarial isonitriles. It is also used for synthetic API such as anesthetic agents and anti-allergic agents.

Uses

4-Acetylbenzonitrile can be used in the preparation of antimalarial isonitriles.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 1613, 1979 DOI: 10.1021/jo01324a006
Tetrahedron Letters, 28, p. 1345, 1987 DOI: 10.1016/S0040-4039(00)95366-8

General Description

The relaxation-assisted two-dimensional infrared (RA 2DIR) spectroscopy of 4-acetylbenzonitrile was analyzed.

Flammability and Explosibility

Not classified

Purification Methods

Recrystallise the nitrile from EtOH [Wagner et al. J Am Chem Soc 108 7727 1986]. [Beilstein 10 H 695, 10 III 3030.]

4-Acetylbenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

4-(1,2,3-THIADIAZOL-4-YL)BENZOIC ACID 4-(1,2,3-THIADIAZOL-4-YL)BENZOYL CHLORIDE 4-(1,2,3-THIADIAZOL-4-YL)BENZONITRILE

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4-Acetylbenzonitrile Suppliers

Americas 1 Belgium 2 Canada 3 China 261 Europe 3 France 2 Germany 8 India 47 Japan 4 Poland 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 22 United States 46 Global 404

Shanghai Taijilin Industrial Co., Ltd.

Tel: 021-50630626 18964684208
Fax: 021-50563898
Email: kate@tajilin.com
Country: China
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Sanover (Xiamen) Technology Co., Ltd

Tel: 05926518632 13876246362
Fax: QQ : 422165847
Email: 422165847@qq.com
Country: China
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Shanghai Hao Yun Chemical Science Co.,Ltd.

Tel: 021-68367562 15002147577;
Fax: 021-68369562
Email: sales@haoyunchem.com
Country: China
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Suzhou dexuan New Material Technology Co., Ltd

Tel: 13773006286
Email: siyzhxl@163.com
Country: China
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Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
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Creasyn Finechem(Tianjin) Co., Ltd.

Tel: 022-83946278 13820503911
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Email: sales@creasyn.com
Country: China
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
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Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

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View Lastest Price from 4-Acetylbenzonitrile manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Acetylbenzonitrile 1443-80-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

Shaanxi Haibo Biotechnology Co., Ltd

Product: 4-Acetylbenzonitrile 1443-80-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-09-01

Qiuxian Baitai New Material Co., LTD

Product: 4-Acetylbenzonitrile 1443-80-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 500ton/Month
Release date: 2021-12-21

1443-80-7, 4-AcetylbenzonitrileRelated Search:

4-(2-Bromoacetyl)benzonitrile Naroparcil 1,4-DIAMINO-2,3-DICYANO-9,10-ANTHRAQUINONE 4-Acetylbenzonitrile 4-CYANOBENZOPHENONE M-ACETYLBENZONITRILE,3-Acetylbenzonitrile97%,3-acetylbenzonitrile,98%,3-ACETYLBENZONITRILE 4-ACETYLBENZONITRILE,P-ACETYLBENZONITRILE 2-ACETYLBENZONITRILE Benzonitrile 4-CYANO-4'-METHOXYBENZOPHENONE 4-[[6-METHOXY-2-(4-METHOXYPHENYL)-3-BENZOFURANYL]CARBONYL]BENZONITRILE 9-OXO-9H-THIOXANTHENE-3-CARBONITRILE-10,10-DIOXIDE 6-(4-CYANOPHENYL)-6-OXOHEXANENITRILE 4-CYANO-3'-METHOXYBENZOPHENONE 4'-CYANO-2,2,2-TRIFLUOROACETOPHENONE 6-CYANO-1-TETRALONE 4-CYANO-2'-METHOXYBENZOPHENONE 5-(4-CYANOPHENYL)-5-OXOVALERONITRILE

4'-Cyanoacetophenonele

4-Cyanophenyl methyl ketone

4-Cyanophenylmethylketone

Benzonitrile, p-acetyl-

Benzonitrile,4-acetyl-

Benzonitrile,p-acetyl-

Methylp-cyanophenylketone

Paracyanoacetophenone

p-Cyanacetophenon

4-CYANOACETOPHENONE

4-ACETYLBENZONITRILE

AKOS 90467

P-ACETYLBENZONITRILE

P-CYANOACETOPHENONE

4-ACETYLBENZONITRILE / 4-CYANOACETOPHENONE

4'-Cyanoacetophenone 4-Acetylbenzonitrile p-Cyanoacetophenone

4-Acetylbenzonitrile99%

4-Acetylbenzonitrile, 98+%

4-AcetyL

4-Acetylbenzonitrile, 98+% 5GR

1-Acetyl-4-benzonitrile

p-Cyanophenyl Methyl Ketone

4'-Cyanoacetophenone, 4-Ethanoylbenzonitrile

4-Acetylbenzonitrile 99%

4-Acetylbenzonitrile, 97+%

4'-caynoacetophenone

4'-Cyanoacetophenone &gt

p-Cyanoacetophenone,99%

4-Cyano acetopheone

Ixaconazole - Intermediate 11（p-cyanoacetophenone）

4-ACETYLBENZONITRILE (25GMS)

4'-Cyanoacetophenone

Isavuconazole Impurity N15

4-Acetylbenzonitrile, 95%

1443-80-7

ARYL ISOCYANATE

Building Blocks

C8 to C9

Organic Building Blocks

Nitrogen Compounds

Cyanides/Nitriles

Building Blocks for Liquid Crystals

Benzonitriles (Building Blocks for Liquid Crystals)

Building Blocks

C8 to C9

Chemical Synthesis

Cyanides/Nitriles

Nitrogen Compounds

Organic Building Blocks

Benzonitriles (Building Blocks for Liquid Crystals)

Building Blocks for Liquid Crystals

Functional Materials

Aromatic Nitriles