ChemicalBook > CAS DataBase List > 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Product Name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- CAS No.
- 28664-35-9
- Chemical Name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Synonyms
- SOTOLON;3-hydroxy-4,5-dimethylfuran-2(5H)-one;3-HYDROXY-4,5-DIMETHYL-2(5H)-FURANONE;SOTOLONE;SUGAR LACTONE;CARAMEL FURANONE;FENUGREEK LACTONE;3-hydroxy-4,5-dimethyl-2(5H)-furanone (sotolon);FEMA 3634;3-hydroxy-4,5-dimethyl-2(5h)-furanon
- CBNumber
- CB6466523
- Molecular Formula
- C6H8O3
- Formula Weight
- 128.13
- MOL File
- 28664-35-9.mol
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4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Property
- Melting point:
- 26-29 °C(lit.)
- Boiling point:
- 184 °C(lit.)
- Density
- 1.049 g/mL at 25 °C
- refractive index
- n20/D 1.491(lit.)
- FEMA
- 3634 | 4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,2-8°C
- pka
- 9.28±0.40(Predicted)
- Odor
- at 0.01 % in propylene glycol. extremely sweet strong caramel maple burnt sugar coffee
- Odor Type
- caramellic
- JECFA Number
- 243
- InChIKey
- UNYNVICDCJHOPO-UHFFFAOYSA-N
- LogP
- -0.44
- CAS DataBase Reference
- 28664-35-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 2(5H)-furanone, 3-hydroxy-4,5-dimethyl-(28664-35-9)
- EPA Substance Registry System
- 2(5H)-Furanone, 3-hydroxy-4,5-dimethyl- (28664-35-9)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- W363499
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Purity
- natural, ≥97%, FG
- Packaging
- SAMPLE-K
- Price
- $220
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363499
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Purity
- natural, ≥97%, FG
- Packaging
- 25G
- Price
- $292
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363499
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Purity
- natural, ≥97%, FG
- Packaging
- 100G
- Price
- $819
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363421
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one solution
- Purity
- 3?wt. % in propylene glycol
- Packaging
- 100g
- Price
- $106
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363421
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one solution
- Purity
- 3?wt. % in propylene glycol
- Packaging
- 1kg
- Price
- $513
- Updated
- 2024/03/01
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4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Chemical Properties,Usage,Production
Chemical Properties
clear yellow liquid
Chemical Properties
3-Hydroxy-4,5-dimethyl-2(5H)-furanone was found in, for example, fenugreek, coffee, sake, and florsherry. Its aroma characteristic changes from caramel-like at low concentrations to curry-like at high concentrations. A method described for its preparation comprises condensation of ethyl propionate with diethyl oxalate and reaction of the intermediately formed diethyl oxalylpropionate with acetaldehyde. Acidic decarboxylation of the ethyl 4,5-dimethyl-2,3-dioxodihydrofuran-4-carboxylate gives the title compound.
Occurrence
Reported found in roasted Virginia tobacco, beef broth, beer, sherry, botryized wine, coffee, tea, fenugreek, sake and rice wine.
Uses
4,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C3 is a labelled analogue of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.
Definition
ChEBI: Sotolone is a butenolide. It has a role as a metabolite.
Aroma threshold values
Aroma characteristics at 1.0%; sweet, strong brown, cyclotene and maple like, caramel, toffee, maltol-like and burnt, brown sugar fenugreek-like, cooked and syrupy.
Taste threshold values
Taste characteristics at 5–25 ppm; sweet, caramel, maple, walnut, brown sugar, nutty, cotton candy, fenugreek and celery-like, rum, roasted meaty with a honey nuance
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 28664-35-9
- Price
- US $1.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-01-17
Henan Fengda Chemical Co., Ltd
- Product
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 28664-35-9
- Price
- US $30.00-0.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-26
Hebei Mojin Biotechnology Co., Ltd
- Product
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 28664-35-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-09-22
28664-35-9, 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-oneRelated Search:
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