ChemicalBook > CAS DataBase List > 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Product Name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- CAS No.
- 28664-35-9
- Chemical Name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Synonyms
- SOTOLON;3-hydroxy-4,5-dimethylfuran-2(5H)-one;3-HYDROXY-4,5-DIMETHYL-2(5H)-FURANONE;SOTOLONE;SUGAR LACTONE;CARAMEL FURANONE;FENUGREEK LACTONE;3-hydroxy-4,5-dimethyl-2(5H)-furanone (sotolon);FEMA 3634;3-hydroxy-4,5-dimethyl-2(5h)-furanon
- CBNumber
- CB6466523
- Molecular Formula
- C6H8O3
- Formula Weight
- 128.13
- MOL File
- 28664-35-9.mol
More
Less
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Property
- Melting point:
- 26-29 °C(lit.)
- Boiling point:
- 184 °C(lit.)
- Density
- 1.049 g/mL at 25 °C
- refractive index
- n20/D 1.491(lit.)
- FEMA
- 3634 | 4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,2-8°C
- pka
- 9.28±0.40(Predicted)
- Odor
- at 0.01 % in propylene glycol. extremely sweet strong caramel maple burnt sugar coffee
- Odor Type
- caramellic
- JECFA Number
- 243
- InChIKey
- UNYNVICDCJHOPO-UHFFFAOYSA-N
- LogP
- -0.44
- CAS DataBase Reference
- 28664-35-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 2(5H)-furanone, 3-hydroxy-4,5-dimethyl-(28664-35-9)
- EPA Substance Registry System
- 2(5H)-Furanone, 3-hydroxy-4,5-dimethyl- (28664-35-9)
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- W363499
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Purity
- natural, ≥97%, FG
- Packaging
- SAMPLE-K
- Price
- $220
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363499
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Purity
- natural, ≥97%, FG
- Packaging
- 25G
- Price
- $292
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363499
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
- Purity
- natural, ≥97%, FG
- Packaging
- 100G
- Price
- $819
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363421
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one solution
- Purity
- 3?wt. % in propylene glycol
- Packaging
- 100g
- Price
- $106
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- W363421
- Product name
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one solution
- Purity
- 3?wt. % in propylene glycol
- Packaging
- 1kg
- Price
- $513
- Updated
- 2024/03/01
More
Less
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Chemical Properties,Usage,Production
Chemical Properties
clear yellow liquid
Chemical Properties
3-Hydroxy-4,5-dimethyl-2(5H)-furanone was found in, for example, fenugreek, coffee, sake, and florsherry. Its aroma characteristic changes from caramel-like at low concentrations to curry-like at high concentrations. A method described for its preparation comprises condensation of ethyl propionate with diethyl oxalate and reaction of the intermediately formed diethyl oxalylpropionate with acetaldehyde. Acidic decarboxylation of the ethyl 4,5-dimethyl-2,3-dioxodihydrofuran-4-carboxylate gives the title compound.
Occurrence
Reported found in roasted Virginia tobacco, beef broth, beer, sherry, botryized wine, coffee, tea, fenugreek, sake and rice wine.
Uses
4,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C3 is a labelled analogue of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.
Definition
ChEBI: Sotolone is a butenolide. It has a role as a metabolite.
Aroma threshold values
Aroma characteristics at 1.0%; sweet, strong brown, cyclotene and maple like, caramel, toffee, maltol-like and burnt, brown sugar fenugreek-like, cooked and syrupy.
Taste threshold values
Taste characteristics at 5–25 ppm; sweet, caramel, maple, walnut, brown sugar, nutty, cotton candy, fenugreek and celery-like, rum, roasted meaty with a honey nuance
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one Suppliers
- Tel
- 027-86637880 17720597715
- Fax
- 027-86637880
- 3271849079@qq.com
- Country
- China
- ProdList
- 436
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 21-62165282 15801962796;
- Fax
- 021 61153784
- bidingchem@163.com
- Country
- China
- ProdList
- 1199
- Advantage
- 60
- Tel
- 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8836
- Advantage
- 52
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3295
- Advantage
- 57
- Tel
- +86 (311) 8573-7996
- Fax
- +86 (311) 8573-9175
- service@lid-ff.cn
- Country
- China
- ProdList
- 294
- Advantage
- 65
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0532-83893697 18561902820
- Fax
- 83893695
- sissili@unitedint.com
- Country
- China
- ProdList
- 352
- Advantage
- 58
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55
- Tel
- 400-400-6206333 18521732826
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9545
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 86-13605431940 13605431940
- Fax
- 0086-0543-2240079
- zpmxchemical@126.com
- Country
- China
- ProdList
- 1401
- Advantage
- 62
- Tel
- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7783
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 15221275939 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 16166
- Advantage
- 55
- Tel
- 18905173768
- Fax
- 025-83263139
- sales@dolonchem.com
- Country
- China
- ProdList
- 2331
- Advantage
- 50
- Tel
- 027-59207879 1972026995 18140587686
- Fax
- QQ：1972026995
- sales@3600chem.com
- Country
- China
- ProdList
- 4660
- Advantage
- 55
- Tel
- 13031698386 18753684562
- Fax
- 0536-8897109
- 1577399715@qq.COM
- Country
- China
- ProdList
- 1707
- Advantage
- 55
- Tel
- 551-65418679 15837135945
- Fax
- 0551-65418697
- info@tnjchem.com
- Country
- China
- ProdList
- 1889
- Advantage
- 62
- Tel
- 18620099427
- Fax
- +86-20-62619665
- amy@howeipharm.com
- Country
- China
- ProdList
- 17687
- Advantage
- 55
- Tel
- 0371-86658258
- Fax
- 0371-60996044
- info@coreychem.com
- Country
- China
- ProdList
- 10453
- Advantage
- 58
- Tel
- 021-52907766-8042
- Fax
- 021-52906523
- Country
- China
- ProdList
- 9941
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 27313
- Advantage
- 60
- Tel
- 400-1166-196 18502815961
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 14603
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 18124570582 TEL：0755-23574479 2355327139
- Fax
- 0755-23229476 QQ: 2355327139
- siliao02@yccreate.com
- Country
- China
- ProdList
- 6116
- Advantage
- 58
- Tel
- 027-59402396 13419635609
- Fax
- 027-83989310
- 13419635609@163.com
- Country
- China
- ProdList
- 1985
- Advantage
- 55
- Tel
- 18029243487 2355327168
- Fax
- 020-31121510
- gy@yccreate.com
- Country
- China
- ProdList
- 4749
- Advantage
- 55
- Tel
- 027-83778875 15807197853
- Fax
- 027-83991220
- 15807197853@163.com
- Country
- China
- ProdList
- 4029
- Advantage
- 58
- Tel
- 13127280945
- 285424065@qq.com
- Country
- China
- ProdList
- 9976
- Advantage
- 55
- Tel
- +86-21-5877 1921
- Fax
- +86-21-5877 1925
- info@chemofchina.com
- Country
- China
- ProdList
- 9653
- Advantage
- 55
- Tel
- 0539-6362799 20）
- Fax
- 0539-6362799（To 20）
- Country
- China
- ProdList
- 10007
- Advantage
- 58
- Tel
- 021-021-52271985 17721149837
- Fax
- +86 (21) 52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 19800
- Advantage
- 60
- Tel
- 021-37581181
- Fax
- 021-57456066
- sales@chem-mall.com
- Country
- China
- ProdList
- 10330
- Advantage
- 58
- Tel
- 18578209868 2355327026
- Fax
- 18578209868 QQ：2355327026
- steroidbest@hotmail.com
- Country
- China
- ProdList
- 6501
- Advantage
- 58
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 400-8210725 18016230971
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25004
- Advantage
- 58
- Tel
- 0086-0551-62993905
- Fax
- 0086-0551-62993905
- info@hxygmall.com
- Country
- China
- ProdList
- 3372
- Advantage
- 58
- Tel
- 021-37590756 57450129
- Fax
- 021-57450128
- Country
- China
- ProdList
- 4284
- Advantage
- 58
- Tel
- 13818478267
- Fax
- -
- 452998455@qq.com
- Country
- China
- ProdList
- 174
- Advantage
- 58
- Tel
- 400-668-9898
- Fax
- 010-51582189
- service@3achem.com
- Country
- China
- ProdList
- 20557
- Advantage
- 58
- Tel
- 027-51837617 15871472056
- Fax
- 027-51837617
- 1659622278@qq.com
- Country
- China
- ProdList
- 417
- Advantage
- 58
- Tel
- 028-85157043 15882256948
- 676046971@qq.com
- Country
- China
- ProdList
- 4397
- Advantage
- 58
- Tel
- 021-000000
- admin@jingshipharmatech.com
- Country
- China
- ProdList
- 9992
- Advantage
- 58
More
Less
View Lastest Price from 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one manufacturers
Hebei Zhuanglai Chemical Trading Co.,Ltd
- Product
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 28664-35-9
- Price
- US $75.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-27
Hebei Weibang Biotechnology Co., Ltd
- Product
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 28664-35-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04
JINING XINHE CHEMICAL CO., LTD
- Product
- 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 28664-35-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10ton
- Release date
- 2024-07-18
28664-35-9, 4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-oneRelated Search:
CHLOROPHOSPHONAZO III
Acetone oxime
Dimethyl phthalate
ETHANE
Dimethyl sulfide
Furazolidone
Spironolactone
Common Fenugreek Seed P.E.
2-Methylfuran
Dimethyl sulfoxide
Dimethyl fumarate
Dimethyl ether
N,N-Dimethylformamide
DIMETHYLGLYOXIME DISODIUM SALT
(-)-Corey lactone diol
TRIOXSALEN
4'-Hydroxyacetophenone
D-(+)-Glucono-1,5-lactone