2-Propanethiol Property

Melting point:

−131 °C(lit.)

Boiling point:

57-60 °C(lit.)

Density 

0.82 g/mL at 25 °C(lit.)

vapor density 

2.6 (vs air)

vapor pressure 

455 mm Hg ( 37.8 °C)

refractive index 

n20/D 1.426(lit.)

FEMA 

3897 | 2-PROPANETHIOL

Flash point:

<−30 °F

storage temp. 

Store below +30°C.

form 

Liquid

pka

pK1:10.86 (25°C,μ=0.1)

color 

Colorless

Odor

Powerful skunk.

Odor Type

alliaceous

Odor Threshold

0.000006ppm

Water Solubility 

Slightly soluble in water

Sensitive 

Air Sensitive

JECFA Number

510

BRN 

605260

Stability:

Stable. Highly flammable - note low flashpoint. May form explosive mixtures with air.

LogP

1.60

CAS DataBase Reference

75-33-2(CAS DataBase Reference)

NIST Chemistry Reference

2-Propanethiol(75-33-2)

EPA Substance Registry System

Isopropyl mercaptan (75-33-2)

Safety

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38-36/38

Safety Statements 

16-26-9-37/39-33

RIDADR 

UN 2402 3/PG 2

WGK Germany 

3

RTECS 

TZ7302000

F 

13

TSCA 

Yes

HS Code 

2930 90 98

HazardClass 

3

PackingGroup 

II

Hazardous Substances Data

75-33-2(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: > 2000 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

2-Propanethiol Chemical Properties,Usage,Production

Chemical Properties

liquid with an exceedingly unpleasant smell

Occurrence

2-Propanethiol is a volatile sulfur compound that is reported to occur in irradiated beef.

Uses

2-Propanethiol is used in preparation of polyol block copolymer. It is also used as standard for petroleum analysis; as intermediate; as natural gas odorant.

Definition

ChEBI: 2-Propanethiol is an alkanethiol that is propane substituted by a sulfanyl group at position 2.

Preparation

2-Propanethiol is synthesised by the reaction of sodium hydrosulfide and brominated isopropane.

General Description

Isopropyl mercaptan is a white liquid with a strong skunk-like odor. (USCG, 1999)

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

2-Propanethiol is incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May liberate hydrogen sulfide when mixed with an acid.

Hazard

Highly flammable, dangerous fire hazard.

Health Hazard

Inhalation causes loss of sense of smell, muscular weakness, convulsions, respiratory paralysis. Ingestion causes nausea and vomiting. Contact with eyes or skin causes irritation.

Purification Methods

Purify it as for propane-1-thiol above. [Beilstein 1 IV 1498.]