ChemicalBook > CAS DataBase List > 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID

3,4-DIHYDROXY-5-METHOXYBENZOIC ACID

Product Name
3,4-DIHYDROXY-5-METHOXYBENZOIC ACID
CAS No.
3934-84-7
Chemical Name
3,4-DIHYDROXY-5-METHOXYBENZOIC ACID
Synonyms
3-O-METHYLGALLATE;RARECHEM AL BE 0702;3-O-methylgallicaci;5-Methoxygallic acid;S-Diacetyl-L-cysteine;3-O-METHYL GALLIC ACID;5-HYDROXYVANILLIC ACID;METHYLGALLIC ACID, 3-O-;5-HYDROXYVANILLIC ACID 97%;4,5-dihydroxy-m-anisic acid
CBNumber
CB6474340
Molecular Formula
C8H8O5
Formula Weight
184.15
MOL File
3934-84-7.mol
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3,4-DIHYDROXY-5-METHOXYBENZOIC ACID Property

Melting point:
220℃
Boiling point:
433.7±45.0 °C(Predicted)
Density 
1.499±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form 
Solid
pka
4.33±0.10(Predicted)
color 
Off-White to Pale Brown
Water Solubility 
Water: 2.2 mg/mL (11.95 mM)
InChI
InChI=1S/C8H8O5/c1-13-6-3-4(8(11)12)2-5(9)7(6)10/h2-3,9-10H,1H3,(H,11,12)
InChIKey
KWCCUYSXAYTNKA-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(OC)=C(O)C(O)=C1
LogP
1.190 (est)
CAS DataBase Reference
3934-84-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36
Safety Statements 
26-36/37/39
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M3669
Product name
3,4-Dihydroxy-5-methoxybenzoic Acid
Purity
min. 95.0 %
Packaging
1G
Price
$173
Updated
2025/07/31
TCI Chemical
Product number
M3669
Product name
3,4-Dihydroxy-5-methoxybenzoic Acid
Purity
min. 95.0 %
Packaging
5G
Price
$519
Updated
2025/07/31
TRC
Product number
D481063
Product name
3,4-Dihydroxy-5-methoxybenzoicAcid
Packaging
50mg
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-0018329
Product name
3-O-Methylgallicacid
Purity
97.74%
Packaging
1g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD70441
Product name
3,4-Dihydroxy-5-methoxybenzoic acid
Packaging
250mg
Price
$72.5
Updated
2021/12/16
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3,4-DIHYDROXY-5-METHOXYBENZOIC ACID Chemical Properties,Usage,Production

Uses

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2][3].

Definition

ChEBI: A member of the class of benzoic acids that is gallic acid in which the phenolic hydroxy group at position 3 is converted to the corresponding methyl ether.

References

[1] Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7. DOI:10.1021/jf9040172
[2] Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9. DOI:10.1002/mc.21974
[3] Gargouri OD, et al. Synthesis of 3-O-methylgallic acid a powerful antioxidant by electrochemical conversion of syringic acid. Biochim Biophys Acta. 2013 Jun;1830(6):3643-9. DOI:10.1016/j.bbagen.2013.02.012

3,4-DIHYDROXY-5-METHOXYBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-DIHYDROXY-5-METHOXYBENZOIC ACID Suppliers

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View Lastest Price from 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID manufacturers

Career Henan Chemical Co
Product
3,4-dihydroxy-5-methoxybenzoic acid 3934-84-7
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

3934-84-7, 3,4-DIHYDROXY-5-METHOXYBENZOIC ACIDRelated Search:

Ellagic acid Methyl 2-amino-3,4,5-trimethoxybenzoate Methyl 3,4,5-trimethoxybenzoate 3,4,5-Trimethoxy benzoic acid SYROSINGOPINE Ethyl 3,4,5-trimethoxybenzoate 3-Hydroxy-4,5-dimethoxybenzoic acid Reserpine Methyl 2-nitro-3,4,5-trimethoxybenzoate 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID 3,4,5-TRIETHOXYBENZOIC ACID Methyl syringate Syringic acid 3,5-DIHYDROXY-4-METHOXYBENZOIC ACID 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER 2,3-DIHYDROXY-4-METHOXYBENZOIC ACID,DIHYDROXY-4-METHOXYBENZOIC ACID,2,3- 3-Methoxybenzoic acid Gallic acid

  • RARECHEM AL BE 0702
  • METHYLGALLIC ACID, 3-O-
  • 4,5-DIHYDROXY-3-METHOXYBENZOIC ACID
  • 3-O-METHYLGALLATE
  • 3-O-METHYL GALLIC ACID
  • 3-METHOXY-4,5-DIHYDROXYBENZOIC ACID
  • 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID
  • METHYLGALLIC ACID, 3-O-(RG)
  • 5-HYDROXYVANILLIC ACID
  • 4,5-dihydroxy-m-anisic acid
  • 5-HYDROXYVANILLIC ACID 97%
  • 4 5-DIHYDROXY-3-METHOXYBENZOICCID 97%
  • 3-METHOXY-4,5-DIHYDROXYBENZOIC ACID 97%
  • Benzoic acid, 3,4-dihydroxy-5-methoxy-
  • 5-Methoxygallic acid
  • 3-O-methylgallicaci
  • S-Diacetyl-L-cysteine
  • 3-O-Methylgallic acid, 10 mM in DMSO
  • 3934-84-7
  • CH3OC6H2OH2COOH
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts