ChemicalBook > CAS DataBase List > (R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane

(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane

Product Name
(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane
CAS No.
197706-50-6
Chemical Name
(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane
Synonyms
Nebivolol Impurity 7;Nebivolol Impurity 24;Nebivolol Impurity 19;(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane;6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-;(2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene;(-)-(R,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran;2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-
CBNumber
CB64747268
Molecular Formula
C11H11FO2
Formula Weight
194.2
MOL File
197706-50-6.mol
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(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Property

Boiling point:
291.7±40.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
vapor pressure 
0.12-0.22Pa at 20-25℃
form 
Liquid:viscous
LogP
2.2-5.2 at 20℃ and pH7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
F595085
Product name
(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane
Packaging
2.5mg
Price
$155
Updated
2021/12/16
TRC
Product number
F595085
Product name
(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane
Packaging
25mg
Price
$1230
Updated
2021/12/16
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(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Chemical Properties,Usage,Production

Uses

(2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane is an intermediate to synthesize Nebivolol (rac, HCl salt, N387900) which is a β1-Adrenergic blocker.

(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane Suppliers

China 20 India 3 United States 1 Global 24
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View Lastest Price from (R)-6-Fluoro-2-[(R)-2-oxiranyl]chromane manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Nebivolol Impurity 29 197706-50-6
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-07
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Nebivolol Impurity 29 197706-50-6
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-07

197706-50-6, (R)-6-Fluoro-2-[(R)-2-oxiranyl]chromaneRelated Search:

(+-)-(R*,S*)-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol 4-Hydroxy Nebivolol, Hydrochloride Hydrate (Mixture of Diastereomers) (-)-Nebivolol Nebivolol Impurity 10 HCl (RS,SR) (2S, 2’S)-6-Fluoro-2-(2’-oxiranyl)chromane Nebivolol Impurity 12 HCl (RR,RR) Nebivolol Impurity 28 HCl (SS,RS) 6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran Ponazuril D-Nebivolol,hydrochloride(1:1) (+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran (2R)-rel-6-Fluoro-3,4-dihydro-2-(2R)-2-oxiranyl-2H-1-benzopyran Defluoro Nebivolol (Mixture of DiastereoMers) (2S)-6-fluoro-2-(oxiran-2-yl)chromane Nebivolol Impurity 2 HCl (SR,RS) NEBIVOLOL HCL Nebivolol (R,R,S,R)-Isomer Nebivolol Impurity 3

  • (-)-(R,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
  • Nebivolol Impurity 19
  • Nebivolol Impurity 24
  • (2R)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene
  • 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-
  • (2R,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane
  • Nebivolol Impurity 7
  • 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-
  • 197706-50-6