N-(4-ACETAMIDOPHENYL)-INDOMETHACIN AMIDE
- Product Name
- N-(4-ACETAMIDOPHENYL)-INDOMETHACIN AMIDE
- CAS No.
- 261766-23-8
- Chemical Name
- N-(4-ACETAMIDOPHENYL)-INDOMETHACIN AMIDE
- Synonyms
- N-4AIA;N-4ACETIA;N-(4-ACETAMIDOPHENYL)-INDOMETHACIN AMIDE;N-(4-ACETAMIDOPHENYL)-1-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETAMIDE;N-(4-ACETAMIDOPHENYL)-1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETAMIDE;1H-Indole-3-acetamide, N-[4-(acetylamino)phenyl]-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-;N-4AcetIA, N-(4-Acetamidophenyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide
- CBNumber
- CB6475024
- Molecular Formula
- C27H24ClN3O4
- Formula Weight
- 489.95
- MOL File
- Mol file
N-(4-ACETAMIDOPHENYL)-INDOMETHACIN AMIDE Property
- Melting point:
- 256-257°C
- storage temp.
- −20°C
- solubility
- DMSO: ≥15 mg/mL
- form
- crystalline
- color
- Pale Yellow
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 70278
- Product name
- N-(4-acetamidophenyl)-Indomethacin amide
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $18
- Updated
- 2024/03/01
- Product number
- 70278
- Product name
- N-(4-acetamidophenyl)-Indomethacin amide
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $73
- Updated
- 2024/03/01
- Product number
- 70278
- Product name
- N-(4-acetamidophenyl)-Indomethacin amide
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $129
- Updated
- 2024/03/01
- Product number
- 70278
- Product name
- N-(4-acetamidophenyl)-Indomethacin amide
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $553
- Updated
- 2024/03/01
- Product number
- A161150
- Product name
- N-(4-Acetamidophenyl)indomethacinAmide
- Packaging
- 5mg
- Price
- $55
- Updated
- 2021/12/16
N-(4-ACETAMIDOPHENYL)-INDOMETHACIN AMIDE Chemical Properties,Usage,Production
Description
N-
Chemical Properties
Pale Yellow Solid
Uses
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant and ovine COX-2 with IC50 of 0.1 uM and 0.625 uM, respectively
Definition
ChEBI: N-(4-acetamidophenyl)-Indomethacin amide is a N-acylindole.
References
[1]. kalgutkar as, marnett ab, crews bc, et al. ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. j med chem. 2000 jul 27;43(15):2860-70.