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DSIP

Product Name
DSIP
CAS No.
62568-57-4
Chemical Name
DSIP
Synonyms
DSIP;WAGGDASGE;DSIP 4H2O;EMIDELTIDE;Delta-Sleep;DSIP acetate;Etipolypeptide;DSIP USP/EP/BP;Ftpp/Adipotide;DSIP nonapeptide
CBNumber
CB6478191
Molecular Formula
C35H48N10O15
Formula Weight
848.82
MOL File
62568-57-4.mol
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DSIP Property

Boiling point:
1522.7±65.0 °C(Predicted)
Density 
1.458±0.06 g/cm3(Predicted)
storage temp. 
−20°C
form 
Powder
pka
3.18±0.10(Predicted)
Water Solubility 
Soluble in water at 0.5mg/ml
Sequence
H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
InChI
InChI=1/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/s3
InChIKey
ZRZROXNBKJAOKB-GFVHOAGBSA-N
SMILES
C(C1=CNC2C=CC=CC1=2)[C@H](N)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@H](C(=O)O)CCC(=O)O |&1:10,15,28,36,41,51,r|
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D4072
Product name
Delta Sleep Inducing Peptide
Packaging
5mg
Price
$142
Updated
2024/03/01
Sigma-Aldrich
Product number
D4072
Product name
Delta Sleep Inducing Peptide
Packaging
25mg
Price
$218.4
Updated
2024/03/01
Alfa Aesar
Product number
J63334
Product name
Delta Sleep-Inducing Peptide
Packaging
1mg
Price
$34.5
Updated
2021/12/16
Alfa Aesar
Product number
J63334
Product name
Delta Sleep-Inducing Peptide
Packaging
5mg
Price
$118
Updated
2021/12/16
Usbiological
Product number
D2732-01B
Product name
Delta Sleep Inducing Peptide
Packaging
25mg
Price
$809
Updated
2021/12/16
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DSIP Chemical Properties,Usage,Production

Description

Delta-sleep-inducing peptide (DSIP) is a neuropeptide with amino acid sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and molecular mass 848.81 g/mol. DSIP occurs in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). Delta-sleep-inducing peptide is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

Uses

Delta-sleep-inducing peptide (DSIP) was isolated, characterized, and synthesized more than 6 years ago. It can help relieve stress and aches that keep you from restful sleep. It was first proposed as a sleep-peptide and this remains the prevalent impression of its function. DSIP is a natural sleep-promoting nonapeptide with a few beneficial functions. The peptide has been used to treat poor sleep, pain conditions, stress-related symptoms, and more. Delta-Sleep Inducing Peptide trifluoroacetate salt H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH trifluoroacetate salt is a useful research chemical compound.

Uses

DSIP is thought to increase sleep regulation, reduce motor activity to improve deep sleep, stimulate ACTH and LH levels, and reportedly normalize blood pressure. DSIP can change the serum level of some hormones, such as adrenocorticotropic hormone, somatostatin, serotonin, etc.

Definition

Emideltide or DSIP is a nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.

benefits

Can restore disturbed sleep patterns;Can promote LH and GH release;Can reduce persistent/chronic pain;Can modulate cortisol production.

Physiological effects

Delta sleep-inducing peptide (DSIP) has several physiological effects in addition to its ability to promote sleep in animals. It is also involved in neuroendocrine regulation and release of anterior pituitary hormones. In rodents and humans, Delta sleep-inducing peptide (DSIP) influence in the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH) and growth hormone (GH). It also plays a role in the regulation of the circadian rhythms and and can help restore disturbed patterns of sleep.

Dosage

DSIP is currently being studied for the treatment of conditions such as narcolepsy, hypertension, and insomnia. It is recommended to inject 0.1 ml of DSIP subcutaneously every day before bedtime for effective results.

DSIP Preparation Products And Raw materials

Raw materials

Preparation Products

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DSIP Suppliers

Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5503
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
028-62328193 17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
2353
Advantage
58
Zhejiang Jiekun Biotechnology Co., Ltd
Tel
0571-88211951 13735518192
Email
sales1@gotopbio.com
Country
China
ProdList
4904
Advantage
58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
Tel
18014456767 18014456767
Email
wenxi@jszkhy.com
Country
China
ProdList
1349
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59101766 13125137661
Email
2853877621@qq.com
Country
China
ProdList
2886
Advantage
58
Dongguan Jiuzhe Biotechnology Co., Ltd
Tel
13316572034
Email
3986929230@qq.com
Country
China
ProdList
80
Advantage
58
Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd
Tel
010-53679529 13801208576
Fax
010-64215766
Email
sales.2@chinazhongshuo.com
Country
China
ProdList
97
Advantage
65
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
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View Lastest Price from DSIP manufacturers

Dorne Chemical Technology co. LTD
Product
DSIP 62568-57-4
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
hebei hongtan Biotechnology Co., Ltd
Product
DSIP 62568-57-4
Price
US $40.00-20.00/box
Min. Order
1box
Purity
99.9%
Supply Ability
5000 box
Release date
2024-03-13
hebei hongtan Biotechnology Co., Ltd
Product
DSIP 62568-57-4
Price
US $40.00-25.00/box
Min. Order
1box
Purity
99.99%
Supply Ability
1000
Release date
2024-03-14

62568-57-4, DSIPRelated Search:


  • SLEEP INDUCING PEPTIDE
  • WAGGDASGE
  • TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU
  • TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU
  • TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O
  • DELTA SLEEP INDUCING PEPTIDE
  • DELTA SLEEP-INDUCING PEPTIDE 4H2O
  • DSIP
  • DSIP 4H2O
  • H-TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU-OH
  • EMIDELTIDE
  • TRP-ALA---ASP-ALA-SER--GLU(TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU)
  • DSIP, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
  • L-Trp-L-Ala-Gly-Gly-L-Asp-L-Ala-L-Ser-Gly-Glu-OH
  • L-Trp-L-Ala-Gly-Gly-L-Asp-L-Ala-L-Ser-Gly-L-Glu-OH
  • Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
  • TRP-ALA-GLY-GLY-ASP-ALA-SER: PO3H2-GLY-GLU [WAGGDA-S: PO3H2-GE]
  • DSIP nonapeptide
  • L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid
  • DSIP, EMideltide
  • Delta sleep inducing peptide, ≥97% (HPLC)
  • DSIP/Delta Sleep Inducing Peptide
  • Deltasleep-inducing peptide (rabbit)
  • Delta-Sleep Inducing Peptide trifluoroacetate salt H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH trifluoroacetate salt
  • Etipolypeptide
  • DSIP USP/EP/BP
  • Ftpp/Adipotide
  • DSIP acetate
  • Emideltide (δ-Sleep Inducing Peptide)
  • Delta-Sleep
  • DSIP Lyophilized Powder
  • Delta Sleep Inducing Peptide Acetate
  • 62568-57-4
  • 9431-45-4
  • C35H48N10O15
  • Peptide
  • 62568-57-4