Ipamorelin
- Product Name
- Ipamorelin
- CAS No.
- 170851-70-4
- Chemical Name
- Ipamorelin
- Synonyms
- IpaMorelin Acetate;Aib-His-D-2-Nal-D-Phe-Lys-NH2;Ipamoreli;IpoMarelin;IPAMORELIN;lpamorelin;NNC-26-0161;IPAMORELIN(5MG);IPAMORELIN(1MG);UNII-Y9M3S784Z6
- CBNumber
- CB41117534
- Molecular Formula
- C38H49N9O5
- Formula Weight
- 711.85
- MOL File
- 170851-70-4.mol
Ipamorelin Property
- Melting point:
- 144-147°C
- Boiling point:
- 1185.5±65.0 °C(Predicted)
- Density
- 1.263±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Acetonitrile (Slightly, Heated), Methanol (Very Slightly), Water (Slightly)
- pka
- 13.04±0.46(Predicted)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C38H49N9O5/c1-38(2,41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7,10-13,15-16,18,22-23,29-32H,8-9,14,17,19-21,39,41H2,1-2H3,(H2,40,48)(H,42,43)(H,44,49)(H,45,50)(H,46,51)(H,47,52)/t29-,30+,31+,32-/m0/s1
- InChIKey
- NEHWBYHLYZGBNO-BVEPWEIPSA-N
- SMILES
- C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@H](CC1N=CNC=1)NC(=O)[C@](C)(C)N
N-Bromosuccinimide Price
- Product number
- SML1322
- Product name
- Ipamorelin acetate
- Purity
- ≥98%
- Packaging
- 10MG
- Price
- $90
- Updated
- 2024/03/01
- Product number
- SML1322
- Product name
- Ipamorelin acetate
- Purity
- ≥98%
- Packaging
- 50MG
- Price
- $347
- Updated
- 2024/03/01
- Product number
- I739415
- Product name
- IpamorelinAcetate
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 452438
- Product name
- Ipamorelin Acetate
- Packaging
- 5mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 5020AF
- Product name
- Ipamorelin
- Packaging
- 5mg
- Price
- $36
- Updated
- 2021/12/16
Ipamorelin Chemical Properties,Usage,Production
Description
Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.It is a pentapeptide with the amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 that was derived from GHRP-1.
Uses
Ipamorelin was originally developed by Novo Nordisk, and was investigated in phase II clinical trials by Helsinn Therapeutics for the treatment of postoperative ileus, but was discontinued due to lack of efficacy.Ipamorelin has been used by athletes as a performance enhancing drug.
Uses
Ipamorelin is a metabolite of growth hormone releasing peptides (GHRPs). Ipamorelin is a pentapeptide with strong growth hormone releasing potency that evokes insulin release from pancrease of normal and diabetic rats.
benefits
Ipamorelin has a wide range of benefits for the human body such as: reduced body fat, increased collagen production, increased lean muscle mass, improved sleep, increased cell repair and regeneration, elevated IGF-1, increased bone mineral content, counteracted glucocorticoid catabolism, decreased appetite stimulation compared to GHRP-6, decreased release of cortisol, prolactin and aldosterone. Decreased release of cortisol, prolactin and aldosterone.
Biochem/physiol Actions
Ipamorelin is a highly selective, potent pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and gastrin mimetic with growth hormone (GH) releasing activity. It mimics gastrin and binds to the gastrin receptor (or growth hormone secretion receptor, GHSR) in the brain, which selectively stimulates the pituitary gland to release growth hormone. This leads to elevated plasma GH levels, which affects many biological processes. In addition to being found in the brain, GHSR is found in the gastrointestinal tract, heart, lungs, liver, kidneys, pancreas, adipose tissue and immune cells. Unlike other growth hormone releasing peptides, ipamorelin stimulates the release of growth hormone only in a manner very similar to that of growth hormone releasing hormone[1].
Side effects
Ipamorelin is generally considered safe and well tolerated, with common side effects including dizziness, headache, nausea, diarrhoea and flushing. Allergic or serious adverse reactions are rare.
References
[1] Ipamorelin[J]. Definitions, 2020. DOI:10.32388/22pzq4.
Ipamorelin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ipamorelin manufacturers
- Product
- Ipamorelin 170851-70-4
- Price
- US $121.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1kg
- Release date
- 2021-06-03
- Product
- Ipamorelin 170851-70-4
- Price
- US $26.00/mg
- Min. Order
- 20mg
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2024-05-11
- Product
- Ipamorelin 170851-70-4
- Price
- US $25.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 1000box/month
- Release date
- 2024-12-26