DSIP

ChemicalBook > CAS DataBase List > DSIP

Product Name: DSIP
CAS No.: 62568-57-4
Chemical Name: DSIP
Synonyms: DSIP;WAGGDASGE;DSIP 4H2O;EMIDELTIDE;Delta-Sleep;DSIP acetate;Etipolypeptide;DSIP USP/EP/BP;Ftpp/Adipotide;DSIP nonapeptide
CBNumber: CB6478191
Molecular Formula: C35H48N10O15
Formula Weight: 848.82
MOL File: 62568-57-4.mol

Less

DSIP Property

Boiling point:: 1522.7±65.0 °C(Predicted)
Density: 1.458±0.06 g/cm3(Predicted)
storage temp.: −20°C
form: Powder
pka: 3.18±0.10(Predicted)
Water Solubility: Soluble in water at 0.5mg/ml
Sequence: H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
InChI: InChI=1/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/s3
InChIKey: ZRZROXNBKJAOKB-GFVHOAGBSA-N
SMILES: C(C1=CNC2C=CC=CC1=2)[C@H](N)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@H](C(=O)O)CCC(=O)O |&1:10,15,28,36,41,51,r|

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D4072
Product name: Delta Sleep Inducing Peptide
Packaging: 5mg
Price: $142
Updated: 2024/03/01

Sigma-Aldrich

Product number: D4072
Product name: Delta Sleep Inducing Peptide
Packaging: 25mg
Price: $218.4
Updated: 2024/03/01

Alfa Aesar

Product number: J63334
Product name: Delta Sleep-Inducing Peptide
Packaging: 1mg
Price: $34.5
Updated: 2021/12/16

Alfa Aesar

Product number: J63334
Product name: Delta Sleep-Inducing Peptide
Packaging: 5mg
Price: $118
Updated: 2021/12/16

Usbiological

Product number: D2732-01B
Product name: Delta Sleep Inducing Peptide
Packaging: 25mg
Price: $809
Updated: 2021/12/16

Less

DSIP Chemical Properties,Usage,Production

Description

Delta-sleep-inducing peptide (DSIP) is a neuropeptide with amino acid sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and molecular mass 848.81 g/mol. DSIP occurs in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). Delta-sleep-inducing peptide is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.

Uses

Delta-sleep-inducing peptide (DSIP) was isolated, characterized, and synthesized more than 6 years ago. It can help relieve stress and aches that keep you from restful sleep. It was first proposed as a sleep-peptide and this remains the prevalent impression of its function. DSIP is a natural sleep-promoting nonapeptide with a few beneficial functions. The peptide has been used to treat poor sleep, pain conditions, stress-related symptoms, and more. Delta-Sleep Inducing Peptide trifluoroacetate salt H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH trifluoroacetate salt is a useful research chemical compound.

Uses

DSIP is thought to increase sleep regulation, reduce motor activity to improve deep sleep, stimulate ACTH and LH levels, and reportedly normalize blood pressure. DSIP can change the serum level of some hormones, such as adrenocorticotropic hormone, somatostatin, serotonin, etc.

Definition

Emideltide or DSIP is a nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.

benefits

Can restore disturbed sleep patterns;Can promote LH and GH release;Can reduce persistent/chronic pain;Can modulate cortisol production.

benefits

Delta sleep-inducing peptide (DSIP), which suppresses excess production of free radicals in the CNS and prevents neuron death during the body’s response to stress. DSIP activates oxidative phosphorylation and increases the resistance of brain neurons to hypoxia in vitro. It decreases the sensitivity of neuron receptors to the excitatory actions of glutamate. Thus, DSIP helps to prevent excitotoxicity, which may underlie its neuroprotective action in cerebral ischemia[1].

References

[1] E. Koplik. “Delta sleep-inducing peptide and Deltaran: Potential approaches to antistress protection.” Neuroscience and Behavioral Physiology 38 1 (2008): 953–957.

Physiological effects

Delta sleep-inducing peptide (DSIP) has several physiological effects in addition to its ability to promote sleep in animals. It is also involved in neuroendocrine regulation and release of anterior pituitary hormones. In rodents and humans, Delta sleep-inducing peptide (DSIP) influence in the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH) and growth hormone (GH). It also plays a role in the regulation of the circadian rhythms and and can help restore disturbed patterns of sleep.

DSIP Preparation Products And Raw materials

Raw materials

Preparation Products

Less

DSIP Suppliers

China 219 France 1 Germany 3 Japan 2 Switzerland 1 United Kingdom 1 United States 16 Global 243

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5503
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303 +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 2358
Advantage: 58

Zhejiang Jiekun Biotechnology Co., Ltd

Tel: 0571-88211951 13735575465
Email: sales1@gotopbio.com
Country: China
ProdList: 4904
Advantage: 58

Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd

Tel: 18014456767 18014456767
Email: wenxi@jszkhy.com
Country: China
ProdList: 1349
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-59101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 3231
Advantage: 58

Dongguan Jiuzhe Biotechnology Co., Ltd

Tel: 13316572034
Email: 3986929230@qq.com
Country: China
ProdList: 80
Advantage: 58

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd

Tel: 010-53679529 13801208576
Fax: 010-64215766
Email: sales.2@chinazhongshuo.com
Country: China
ProdList: 97
Advantage: 65

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7854
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9635
Advantage: 58

Hangzhou Peptide Biochem Co.,Ltd

Tel: 0571-89197072; 18668118770
Fax: 0571-89197072
Email: linda@peptide-china.com
Country: China
ProdList: 248
Advantage: 56

Watson Biotechnology Co.,Ltd

Tel: 027-027-59207879 18140587686
Fax: QQ：1972026995
Email: kf@3600chem.com
Country: China
ProdList: 4697
Advantage: 55

Avantpbc Chemical Tech(Shanghai) Co,Ltd.

Tel: 17802107445
Country: China
ProdList: 185
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9947
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

Shanghai SuperLan Chemcial Technique Centre

Tel: 021-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 9038
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

Shenzhen Simeiquan Biotechnology Co. Ltd

Tel: 18126413629 0755-23311925 2355327053
Fax: 0755-23311925
Email: abel@ycgmp.com
Country: China
ProdList: 5115
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Shenzhen Sendi Biological Technology Co., Ltd.

Tel: 18124570582 TEL：0755-23574479 2355327139
Fax: 0755-23229476 QQ: 2355327139
Email: siliao02@yccreate.com
Country: China
ProdList: 6120
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-025-58361106-805-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9962
Advantage: 55

Zhuhai JiaYi Biological Technology Co., Ltd.

Tel: 18578209868 2355327026
Fax: 18578209868 QQ：2355327026
Email: steroidbest@hotmail.com
Country: China
ProdList: 6504
Advantage: 58

Hubei widely chemical technology Co., Ltd.

Tel: 027-83778895 18602735115
Fax: 027-51119224
Email: 18602735115@163.com
Country: China
ProdList: 1999
Advantage: 64

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: eric@peptidego.com
Country: China
ProdList: 6347
Advantage: 58

Foshan DaoQi Biological Co., Ltd.

Tel: 18062666947
Fax: 18062666959
Email: 2355880548@qq.com
Country: China
ProdList: 4229
Advantage: 58

Shanghai Chain peptide Biological Co., Ltd.

Tel: +86 18516118859
Fax: +86 (21) 2096 2272
Email: sales@chainpeptide.com
Country: CHINA
ProdList: 420
Advantage: 58

Sichuan Jisheng Biopharmaceutical Co.,Ltd.

Tel: +86-0833-2598983 +86-18086877136
Fax: +86-833-2598903
Email: Nyx-peptide@jsjpharm.cn
Country: China
ProdList: 306
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3063
Advantage: 58

Guangzhou Belka Biological Technology Co., Ltd.

Tel: +86-18665676617
Fax: 18665676617
Country: China
ProdList: 958
Advantage: 58

Hebei Yime New Material Technology Co., Ltd.

Tel: +86-66697723 +86-17703311139
Email: admin@china-yime.com
Country: China
ProdList: 563
Advantage: 58

Shanghai Yunao International Trade Co., Ltd

Tel: +8617621705551
Email: asdf@shanghaihg.cn
Country: China
ProdList: 265
Advantage: 58

Hebei Mojin Biotechnology Co., Ltd

Tel: +8613288715578
Email: sales@hbmojin.com
Country: China
ProdList: 12471
Advantage: 58

Finetech Industry Limited

Tel: +86-27-87465837 +8618971612321
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9635
Advantage: 58

Shijiazhuang Gantuo Biotechnology Co., Ltd

Tel: +8613373514458
Email: gantuo02@cngantuo.com
Country: China
ProdList: 218
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10523
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: 0551-65418671
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34572
Advantage: 58

XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD

Tel: +8617731987558
Email: xingjiu@xingjiubiotech.com
Country: China
ProdList: 990
Advantage: 58

Wuhan Demeikai Biotechnology Co., Ltd

Tel: +8618942921723
Email: info@dmksw.xin
Country: China
ProdList: 723
Advantage: 58

Wuhan Golt Biotech Co., Ltd.

Tel: +8615389281203
Email: maria@goltbiotech.com
Country: China
ProdList: 980
Advantage: 58

Hebei Qige Biological Technology Co. Ltd

Tel: +86 +8618733132031
Country: CHINA
ProdList: 1313
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10326
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 0571-88211921
Email: sales1@gotopbio.com
Country: CHINA
ProdList: 2609
Advantage: 58

Qiuxian Baitai New Material Co., LTD

Tel: +8618330912755
Fax: +8619932103556
Email: sale2@hbyalin.com
Country: China
ProdList: 1677
Advantage: 58

Less

View Lastest Price from DSIP manufacturers

Dorne Chemical Technology co. LTD

Product: DSIP 62568-57-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2024-03-26

hebei hongtan Biotechnology Co., Ltd

Product: DSIP 62568-57-4
Price: US $40.00-20.00/box
Min. Order: 1box
Purity: 99.9%
Supply Ability: 5000 box
Release date: 2024-03-13

hebei hongtan Biotechnology Co., Ltd

Product: DSIP 62568-57-4
Price: US $40.00-25.00/box
Min. Order: 1box
Purity: 99.99%
Supply Ability: 1000
Release date: 2024-03-14

62568-57-4, DSIPRelated Search:

Ipamorelin Eptifibatide Acetate Vantas Elamipretide DSIP N-Acetyl-L-glutamic acid Delta Sleep Inducing Peptide [Tyr0] (DSIP) DSIP (PHOSPHO),PHOSPHO-DSIP H-GLY-GLY-GLU-OH Delta Sleep Inducing Peptide, phosphorylated (DSIP) Delta Sleep Inducing Peptide (DSIP) [Trp-Ala-Gly-Gly-Asp(Ala-Ser-Gly-Glu-OH)-OH] Delta Sleep Inducing Peptide (DSIP) [Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu] Delta Sleep Inducing Peptide (DSIP) 4-Ala-dsip-NH2 (TYR1)-DSIP (ASN5)-DSIP Delta Sleep Inducing Peptide (DSIP) [Trp-Ala-Gly-Gly-Asp(Ala-Ser-Gly-Glu-OH)-NH2] Delta Sleep Inducing Peptide (DSIP), Rabbit anti-

SLEEP INDUCING PEPTIDE

WAGGDASGE

TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU

TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU

TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O

DELTA SLEEP INDUCING PEPTIDE

DELTA SLEEP-INDUCING PEPTIDE 4H2O

DSIP

DSIP 4H2O

H-TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU-OH

EMIDELTIDE

TRP-ALA---ASP-ALA-SER--GLU(TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU)

DSIP, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

L-Trp-L-Ala-Gly-Gly-L-Asp-L-Ala-L-Ser-Gly-Glu-OH

L-Trp-L-Ala-Gly-Gly-L-Asp-L-Ala-L-Ser-Gly-L-Glu-OH

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH

TRP-ALA-GLY-GLY-ASP-ALA-SER: PO3H2-GLY-GLU [WAGGDA-S: PO3H2-GE]

DSIP nonapeptide

L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid

DSIP, EMideltide

Delta sleep inducing peptide, ≥97% (HPLC)

DSIP/Delta Sleep Inducing Peptide

Deltasleep-inducing peptide (rabbit)

Delta-Sleep Inducing Peptide trifluoroacetate salt H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH trifluoroacetate salt

Etipolypeptide

DSIP USP/EP/BP

Ftpp/Adipotide

DSIP acetate

Emideltide (δ-Sleep Inducing Peptide)

Delta-Sleep

DSIP Lyophilized Powder

Delta Sleep Inducing Peptide Acetate

δ-Sleep Inducing Peptide acetate

62568-57-4

9431-45-4

C35H48N10O15

Peptide

62568-57-4