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Lapatinib 2-Fluoro Impurity

Product Name
Lapatinib 2-Fluoro Impurity
CAS No.
1393112-45-2
Chemical Name
Lapatinib 2-Fluoro Impurity
Synonyms
Lapatinib Impurity 45;Lapatinib 2-Fluoro Analog;N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine;N-[3-Chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine;4-Quinazolinamine, N-[3-chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-;N-(3-chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)
CBNumber
CB64798275
Molecular Formula
C29H26ClFN4O4S
Formula Weight
581.06
MOL File
1393112-45-2.mol
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Lapatinib 2-Fluoro Impurity Property

Boiling point:
752.5±60.0 °C(Predicted)
Density 
1.381±0.06 g/cm3(Predicted)
pka
6.34±0.19(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D291118
Product name
3-Desfluoro2-FluoroLapatinib
Packaging
10mg
Price
$925
Updated
2021/12/16
TRC
Product number
D291118
Product name
3-Desfluoro2-FluoroLapatinib
Packaging
25mg
Price
$1760
Updated
2021/12/16
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Lapatinib 2-Fluoro Impurity Chemical Properties,Usage,Production

Uses

3-Desfluoro 2-Fluoro Lapatinib is a compound related to drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.

Lapatinib 2-Fluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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1393112-45-2, Lapatinib 2-Fluoro ImpurityRelated Search:


  • Lapatinib Impurity 45
  • Lapatinib 2-Fluoro Analog
  • N-(3-chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)
  • N-[3-Chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine
  • N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
  • 4-Quinazolinamine, N-[3-chloro-4-[(2-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-
  • 1393112-45-2