MLN-4760
- Product Name
- MLN-4760
- CAS No.
- 305335-31-3
- Chemical Name
- MLN-4760
- Synonyms
- MLN-4760;((S)-1-carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine;L-Histidine, N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-;inhibit,Angiotensin-converting Enzyme (ACE),MLN 4760,Inhibitor,MLN-4760,MLN4760;(2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)methyl]-1H-imidazol-5-yl}ethyl]amino}-4-methylpentanoic acid
- CBNumber
- CB64845021
- Molecular Formula
- C19H23Cl2N3O4
- Formula Weight
- 428.31
- MOL File
- 305335-31-3.mol
MLN-4760 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A solid
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P330Rinse mouth.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 5.30616
- Product name
- ACE2 Inhibitor, MLN-4760
- Purity
- ≥97% (HPLC), powder, Calbiochem?
- Packaging
- 2MG
- Price
- $273
- Updated
- 2023/01/07
- Product number
- CS-0015513
- Product name
- MLN-4760
- Purity
- 99.93%
- Packaging
- 1mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0015513
- Product name
- MLN-4760
- Purity
- 99.93%
- Packaging
- 5mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- CS-0015513
- Product name
- MLN-4760
- Purity
- 99.93%
- Packaging
- 10mg
- Price
- $800
- Updated
- 2021/12/16
- Product number
- CS-0015513
- Product name
- MLN-4760
- Purity
- 99.93%
- Packaging
- 25mg
- Price
- $1700
- Updated
- 2021/12/16
MLN-4760 Chemical Properties,Usage,Production
Definition
ChEBI: MLN-4760 is a L-histidine derivative that is L-histidine in which a hydrogen of the primary amino group is substituted by a (1S)-1-carboxy-3-methylbutyl group and the ring NH group is substituted by a 3,5-dichlorobenzyl group. It is a potent and selective human angiotensin-converting enzyme 2 (ACE2) inhibitor (IC50 = 0.44 nM) which was in clinical development for the treatment of ulcerative colitis. It has a role as an anti-inflammatory agent and an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. It is a L-histidine derivative, a dichlorobenzene and a L-leucine derivative.
storage
Store at -20°C
MLN-4760 Preparation Products And Raw materials
Raw materials
Preparation Products
MLN-4760 Suppliers
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- China
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