Cyclopropylmagnesium bromide Property

Boiling point:

65 °C

Density 

0.968 g/mL at 25 °C

Flash point:

65°C

storage temp. 

2-8°C

form 

Turbid Liquid

color 

Yellow to green

Water Solubility 

Soluble in water (17 mg/ml), (25°C). Soluble in organic solvents.

Sensitive 

Air & Moisture Sensitive

InChIKey

QUPLLJGAJVXXBW-UHFFFAOYSA-M

CAS DataBase Reference

23719-80-4(CAS DataBase Reference)

Safety

Hazard Codes 

F,Xi,C

Risk Statements 

11-14-19-36/37/38-40-37-34

Safety Statements 

16-26-45-36/37/39

RIDADR 

UN 3399 4.3/PG 2

WGK Germany 

1

HazardClass 

4.3

PackingGroup 

II

HS Code 

29319090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H260In contact with water releases flammable gases which may ignite spontaneously

H261In contact with water releases flammable gas

H302Harmful if swallowed

H313May be harmful in contact with skin

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H333May be harmful if inhaled

H335May cause respiratory irritation

H351Suspected of causing cancer

H371May cause damage to organs

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P231+P232Handle under inert gas. Protect from moisture.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P335+P334Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.

P370+P378In case of fire: Use … for extinction.

P402+P404Store in a dry place. Store in a closed container.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

Cyclopropylmagnesium bromide Chemical Properties,Usage,Production

Chemical Properties

Clear colorless solution

Uses

It often acts as the starting nutrient mix for dropout studies where fermentation conditions required the absence of one or more essential amino acids. For classifying Yeasts based on colonial characteristics and cell morphology.

Uses

Cyclopropylmagnesium bromide solution has been used in Grignard reaction that finds application as the key step in the preparation of aminopropylindenes, a chemotype of oxidosqualene cyclase (OSC) inhibitors from Grundmann′s ketone. It can react with trimethylborate to form cyclopropylboronic acid, which can undergo Suzuki-type coupling reactions with different aryl, and heteroaryl bromides to form the cyclopropyl adducts.

Uses

Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF)

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

General Description

This product, 1.0 M in 2-methyltetrahydrofuran aligns with Safer Solvents and Auxiliaries, Use of Renewable Feedstocks and Inherently Safer Chemistry for Accident Prevention.