1,1-Bis(hydroxymethyl)cyclopropane

Product Name: 1,1-Bis(hydroxymethyl)cyclopropane
CAS No.: 39590-81-3
Chemical Name: 1,1-Bis(hydroxymethyl)cyclopropane
Synonyms: CYCLOPROPANE-1,1-DIYLDIMETHANOL;1,1-DIMETHYLCYCLOPROPANE;CYCLOPROPANE DIMETHANOL;1,1-Cyclopropyldimethanol;1,1-Cyclopropyl;1,1-Cyclopropane;1,1-Bis(hydroxymethy;1,1-Bis(hydroxymethyL;cyclopropyl dimethanol;1,1-DIMETHOLCYCLOPROPANE
CBNumber: CB9231254
Molecular Formula: C5H10O2
Formula Weight: 102.13
MOL File: 39590-81-3.mol

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1,1-Bis(hydroxymethyl)cyclopropane Property

Boiling point:: 235-236 °C(lit.)
Density: 1.065 g/mL at 25 °C(lit.)
refractive index: n20/D 1.4700(lit.)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Ethyl Acetate (Slightly)
pka: 14.80±0.10(Predicted)
form: Colourless to Off-White Oil to Semi-Solid
Specific Gravity: 1.065
color: Colorless to Light yellow to Light orange
InChI: InChI=1S/C5H10O2/c6-3-5(4-7)1-2-5/h6-7H,1-4H2
InChIKey: YAINYZJQSQEGND-UHFFFAOYSA-N
SMILES: C1(CO)(CO)CC1
CAS DataBase Reference: 39590-81-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29021990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 546569
Product name: 1,1-Bis(hydroxymethyl)cyclopropane
Purity: 90%
Packaging: 5g
Price: $61.18
Updated: 2025/07/31

TCI Chemical

Product number: B5365
Product name: 1,1-Bis(hydroxymethyl)cyclopropane
Purity: >96.0%(GC)
Packaging: 5g
Price: $20
Updated: 2025/07/31

TCI Chemical

Product number: B5365
Product name: 1,1-Bis(hydroxymethyl)cyclopropane
Purity: >96.0%(GC)
Packaging: 25g
Price: $56
Updated: 2025/07/31

TRC

Product number: B445050
Product name: 1,1-Bis(hydroxymethyl)cyclopropane
Packaging: 250g
Price: $450
Updated: 2021/12/16

AK Scientific

Product number: J92468
Product name: 1,1-Bis(hydroxymethyl)cyclopropane
Packaging: 1kg
Price: $600
Updated: 2021/12/16

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1,1-Bis(hydroxymethyl)cyclopropane Chemical Properties,Usage,Production

Chemical Properties

Colorless to yellow liquid

Uses

1,1-Bis(hydroxymethyl)cyclopropane is used in the synthesis of morphine alkaloids. It also serves as an inhibitor of 5-lipoxygenase.

Synthesis

6914-71-2

39590-81-3

The general procedure for the synthesis of 1,1-cyclopropanedimethanol from dimethyl 1,1-cyclopropanedicarboxylate was as follows: lithium aluminum hydride (LiAlH4, 569 mg, 15.0 mmol) was added batchwise to a solution of dimethyl-1,1-cyclopropanedicarboxylate (791 mg, 5.01 mmol) in ether (Et2O, 20 mL) at 0 °C. The reaction mixture was stirred at room temperature for 4 h. The reaction was subsequently quenched with saturated sodium sulfate (Na2SO4) solution at 0 °C. The precipitated solid was filtered and washed with tetrahydrofuran (THF). The filtrate was concentrated and purified by column chromatography (eluent: ethyl acetate, EtOAc) to afford 440 mg (86% yield) of the target product 1,1-cyclopropanedimethanol. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 4.02 (s, 2H), 3.56 (s, 4H), 0.48 (s, 4H); mass spectrum (electrospray ionization, ES) m/z: 125 ([M + Na]+).

References

[1] Patent: WO2005/30694, 2005, A1. Location in patent: Page/Page column 84-85
[2] Patent: WO2005/12324, 2005, A2. Location in patent: Page/Page column 106-107
[3] Patent: WO2014/209034, 2014, A1. Location in patent: Paragraph 580; 581; 582

1,1-Bis(hydroxymethyl)cyclopropane Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1-Bis(hydroxymethyl)cyclopropane Suppliers

Americas 1 Canada 2 China 301 Europe 3 Germany 2 India 9 Japan 2 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 9 United States 27 Global 361

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View Lastest Price from 1,1-Bis(hydroxymethyl)cyclopropane manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,1-Bis(hydroxymethyl)cyclopropane 39590-81-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-05

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,1-Bis(hydroxymethyl)cyclopropane 39590-81-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

Dideu Industries Group Limited

Product: 1,1-Bis(hydroxymethyl)cyclopropane 39590-81-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2025-04-08

39590-81-3, 1,1-Bis(hydroxymethyl)cyclopropaneRelated Search:

Malononitrile Tris(hydroxymethyl)nitromethane Benzhydrol Cyclopropane Diethyl malonate Dimethyl malonate Malonic acid propanedial Cyclopropyl carbinol 1,3-Diaminopropane Cyclopropanecarboxylic acid Bromoacetaldehyde dimethyl acetal Aminoacetaldehyde dimethyl acetal 1,1-Cyclopropanedicarboxylic acid 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE 1,1-CYCLOPROPANEDICARBOXYLIC ACID MONOETHYL ESTER 1,1-Cyclopropanedicarboxylic acid monomethyl ester Diethyl 1,1-cyclopropanedicarboxylate

CYCLOPROPYLIDENEDIMETHANOL

CYCLOPROPANE DIMETHANOL

1,1-BIS(HYDROXYMETHYL)CYCLOPROPANE

1,1-CYCLOPROPANEDIMETHANOL

1,1-DIMETHYLCYCLOPROPANE

(1-HYDROXYMETHYLCYCLOPROPYL)METHANOL

1,1-Cyclopropane dimethanlol

1,1-Cyclopropyldimethanol

cyclopropyl dimethanol

1,1-DIMETHOLCYCLOPROPANE

1,1-BIS(HYDROMETHYL)CYCLOPROPANE

CYCLOPROPANE-1,1-DIYLDIMETHANOL

1,1-Cyclopropane

1,1-Bis(hydroxymethyl)cyclopropane 97%

1,1-BIS(HYDROXYMETHYLCYCLOPROPANE) 98+%

1,1-Bis(hydroxymethy

1-Bis(hydroMethyl)cyclopropane

1,1-Bis(hydroxymethyl)cycloproane

1,1-Bis(hydroxymethyl)cyclop

1,1-Bis(hydroxyMethyl)cyclopropane, tech. 90%

(Cyclopropane-1,1-diyl)dimethanol 97%

1,1-Bis(hydroxymethyl)cyclopropane , [1-(Hydroxymethyl)cyclopropyl]methanol

Cyclopropyl-1,1-dimethanol

1,1-Bis(hydroxymethyL

1,1-cyclopropane dimethyl alcohol

1,1-Bis(hydroxycyclopropane

1,1-Bis(hydroxymethyl)cyclopropance

1,1-Cyclopropyl

1,1-Cyclopropanedimethanol (6CI, 7CI, 9CI, ACI)

1,1-Bis(hydroxymethyl)cyclopropaneCyclopropyldimethanol

Cyclopropanedimethanol, 90%

Cyclopropan-1,1-diyldimethanol

39590-81-3

HOCH22C3H4

Building Blocks

Organic Building Blocks

Oxygen Compounds

Polyols

Thiophenes

Hydroxymethyl's

Alkohols

API intermediates

Ring Systems

Propanes/propenes