ChemicalBook > CAS DataBase List > 1,1-Bis(hydroxymethyl)cyclopropane

1,1-Bis(hydroxymethyl)cyclopropane

Product Name
1,1-Bis(hydroxymethyl)cyclopropane
CAS No.
39590-81-3
Chemical Name
1,1-Bis(hydroxymethyl)cyclopropane
Synonyms
CYCLOPROPANE-1,1-DIYLDIMETHANOL;1,1-DIMETHYLCYCLOPROPANE;CYCLOPROPANE DIMETHANOL;1,1-Cyclopropyldimethanol;1,1-Cyclopropyl;1,1-Cyclopropane;1,1-Bis(hydroxymethy;1,1-Bis(hydroxymethyL;cyclopropyl dimethanol;1,1-DIMETHOLCYCLOPROPANE
CBNumber
CB9231254
Molecular Formula
C5H10O2
Formula Weight
102.13
MOL File
39590-81-3.mol
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1,1-Bis(hydroxymethyl)cyclopropane Property

Boiling point:
235-236 °C(lit.)
Density 
1.065 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.4700(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate (Slightly)
pka
14.80±0.10(Predicted)
form 
Colourless to Off-White Oil to Semi-Solid
Specific Gravity
1.065
color 
Colorless to Light yellow to Light orange
InChI
InChI=1S/C5H10O2/c6-3-5(4-7)1-2-5/h6-7H,1-4H2
InChIKey
YAINYZJQSQEGND-UHFFFAOYSA-N
SMILES
C1(CO)(CO)CC1
CAS DataBase Reference
39590-81-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29021990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
546569
Product name
1,1-Bis(hydroxymethyl)cyclopropane
Purity
90%
Packaging
5g
Price
$61.18
Updated
2025/07/31
TCI Chemical
Product number
B5365
Product name
1,1-Bis(hydroxymethyl)cyclopropane
Purity
>96.0%(GC)
Packaging
5g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
B5365
Product name
1,1-Bis(hydroxymethyl)cyclopropane
Purity
>96.0%(GC)
Packaging
25g
Price
$56
Updated
2025/07/31
TRC
Product number
B445050
Product name
1,1-Bis(hydroxymethyl)cyclopropane
Packaging
250g
Price
$450
Updated
2021/12/16
AK Scientific
Product number
J92468
Product name
1,1-Bis(hydroxymethyl)cyclopropane
Packaging
1kg
Price
$600
Updated
2021/12/16
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1,1-Bis(hydroxymethyl)cyclopropane Chemical Properties,Usage,Production

Chemical Properties

Colorless to yellow liquid

Uses

1,1-Bis(hydroxymethyl)cyclopropane is used in the synthesis of morphine alkaloids. It also serves as an inhibitor of 5-lipoxygenase.

Synthesis

6914-71-2

39590-81-3

The general procedure for the synthesis of 1,1-cyclopropanedimethanol from dimethyl 1,1-cyclopropanedicarboxylate was as follows: lithium aluminum hydride (LiAlH4, 569 mg, 15.0 mmol) was added batchwise to a solution of dimethyl-1,1-cyclopropanedicarboxylate (791 mg, 5.01 mmol) in ether (Et2O, 20 mL) at 0 °C. The reaction mixture was stirred at room temperature for 4 h. The reaction was subsequently quenched with saturated sodium sulfate (Na2SO4) solution at 0 °C. The precipitated solid was filtered and washed with tetrahydrofuran (THF). The filtrate was concentrated and purified by column chromatography (eluent: ethyl acetate, EtOAc) to afford 440 mg (86% yield) of the target product 1,1-cyclopropanedimethanol. The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 4.02 (s, 2H), 3.56 (s, 4H), 0.48 (s, 4H); mass spectrum (electrospray ionization, ES) m/z: 125 ([M + Na]+).

References

[1] Patent: WO2005/30694, 2005, A1. Location in patent: Page/Page column 84-85
[2] Patent: WO2005/12324, 2005, A2. Location in patent: Page/Page column 106-107
[3] Patent: WO2014/209034, 2014, A1. Location in patent: Paragraph 580; 581; 582

1,1-Bis(hydroxymethyl)cyclopropane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,1-Bis(hydroxymethyl)cyclopropane manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1,1-Bis(hydroxymethyl)cyclopropane 39590-81-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-05
Hebei Chuanghai Biotechnology Co., Ltd
Product
1,1-Bis(hydroxymethyl)cyclopropane 39590-81-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Dideu Industries Group Limited
Product
1,1-Bis(hydroxymethyl)cyclopropane 39590-81-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2025-04-08

39590-81-3, 1,1-Bis(hydroxymethyl)cyclopropaneRelated Search:

Malononitrile Tris(hydroxymethyl)nitromethane Benzhydrol Cyclopropane Diethyl malonate Dimethyl malonate Malonic acid propanedial Cyclopropyl carbinol 1,3-Diaminopropane Cyclopropanecarboxylic acid Bromoacetaldehyde dimethyl acetal Aminoacetaldehyde dimethyl acetal 1,1-Cyclopropanedicarboxylic acid 6,6-DIMETHYL-5,7-DIOXASPIRO[2.5]OCTANE-4,8-DIONE 1,1-CYCLOPROPANEDICARBOXYLIC ACID MONOETHYL ESTER 1,1-Cyclopropanedicarboxylic acid monomethyl ester Diethyl 1,1-cyclopropanedicarboxylate

  • CYCLOPROPYLIDENEDIMETHANOL
  • CYCLOPROPANE DIMETHANOL
  • 1,1-BIS(HYDROXYMETHYL)CYCLOPROPANE
  • 1,1-CYCLOPROPANEDIMETHANOL
  • 1,1-DIMETHYLCYCLOPROPANE
  • (1-HYDROXYMETHYLCYCLOPROPYL)METHANOL
  • 1,1-Cyclopropane dimethanlol
  • 1,1-Cyclopropyldimethanol
  • cyclopropyl dimethanol
  • 1,1-DIMETHOLCYCLOPROPANE
  • 1,1-BIS(HYDROMETHYL)CYCLOPROPANE
  • CYCLOPROPANE-1,1-DIYLDIMETHANOL
  • 1,1-Cyclopropane
  • 1,1-Bis(hydroxymethyl)cyclopropane 97%
  • 1,1-BIS(HYDROXYMETHYLCYCLOPROPANE) 98+%
  • 1,1-Bis(hydroxymethy
  • 1-Bis(hydroMethyl)cyclopropane
  • 1,1-Bis(hydroxymethyl)cycloproane
  • 1,1-Bis(hydroxymethyl)cyclop
  • 1,1-Bis(hydroxyMethyl)cyclopropane, tech. 90%
  • (Cyclopropane-1,1-diyl)dimethanol 97%
  • 1,1-Bis(hydroxymethyl)cyclopropane , [1-(Hydroxymethyl)cyclopropyl]methanol
  • Cyclopropyl-1,1-dimethanol
  • 1,1-Bis(hydroxymethyL
  • 1,1-cyclopropane dimethyl alcohol
  • 1,1-Bis(hydroxycyclopropane
  • 1,1-Bis(hydroxymethyl)cyclopropance
  • 1,1-Cyclopropyl
  • 1,1-Cyclopropanedimethanol (6CI, 7CI, 9CI, ACI)
  • 1,1-Bis(hydroxymethyl)cyclopropaneCyclopropyldimethanol
  • Cyclopropanedimethanol, 90%
  • Cyclopropan-1,1-diyldimethanol
  • 39590-81-3
  • HOCH22C3H4
  • Building Blocks
  • Organic Building Blocks
  • Oxygen Compounds
  • Polyols
  • Thiophenes
  • Hydroxymethyl's
  • Alkohols
  • API intermediates
  • Ring Systems
  • Propanes/propenes