Cyclopropyl carbinol
Description Referrence- Product Name
- Cyclopropyl carbinol
- CAS No.
- 2516-33-8
- Chemical Name
- Cyclopropyl carbinol
- Synonyms
- CYCLOPROPYLMETHANOL;CYCLOPROPANEMETHANOL;CPMO;CP-CARBINOL;(HYDROXYMETHYL)CYCLOPROPANE;CPC-OL;Cyclopropylmethane;RARECHEM AK ML 0580;CYCLOPROPYL CARBINOL;CYCLPOPROPANEMETHANOL
- CBNumber
- CB1254806
- Molecular Formula
- C4H8O
- Formula Weight
- 72.11
- MOL File
- 2516-33-8.mol
Cyclopropyl carbinol Property
- Melting point:
- -60 °C
- Boiling point:
- 123-124 °C738 mm Hg(lit.)
- Density
- 0.89 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.431(lit.)
- Flash point:
- 95 °F
- storage temp.
- Flammables area
- solubility
- Chloroform, Ethyl Acetate
- pka
- 15.10±0.10(Predicted)
- form
- Liquid
- color
- Clear colorless
- Specific Gravity
- 0.890
- Water Solubility
- miscible
- BRN
- 1846846
- InChIKey
- GUDMZGLFZNLYEY-UHFFFAOYSA-N
- CAS DataBase Reference
- 2516-33-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Cyclopropyl carbinol(2516-33-8)
- EPA Substance Registry System
- Cyclopropanemethanol (2516-33-8)
Safety
- Hazard Codes
- Xn,Xi,C,F
- Risk Statements
- 10-22-36-34
- Safety Statements
- 16-26-36-45-36/37/39
- RIDADR
- UN 1987 3/PG 3
- WGK Germany
- 1
- RTECS
- GZ2212250
- Hazard Note
- Irritant
- TSCA
- Yes
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29061990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 482099
- Product name
- Cyclopropanemethanol
- Purity
- ≥99.5%
- Packaging
- 25ml
- Price
- $67.8
- Updated
- 2024/03/01
- Product number
- 482099
- Product name
- Cyclopropanemethanol
- Purity
- ≥99.5%
- Packaging
- 1l
- Price
- $384.6
- Updated
- 2024/03/01
- Product number
- C0982
- Product name
- Cyclopropanemethanol
- Purity
- >98.0%(GC)
- Packaging
- 5mL
- Price
- $20
- Updated
- 2024/03/01
- Product number
- C0982
- Product name
- Cyclopropanemethanol
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $37
- Updated
- 2024/03/01
- Product number
- A12567
- Product name
- Cyclopropanemethanol, 98%
- Packaging
- 5g
- Price
- $27.65
- Updated
- 2024/03/01
Cyclopropyl carbinol Chemical Properties,Usage,Production
Description
Cyclopropyl carbinol (also known as Cyclopropanemethanol) is an anaesthetic. Cyclopropyl Carbinol is used as an intermediate for pharmaceuticals, agrochemical, and other organic synthesis such as for the applications for electronics chemicals, polymer additives, coatings, adhesives, surfactants, and other applications3. It can also be used for the preparation of cyclopropanecarbaldehyde, cyclopropylmethylsulfonate and dibenzyl cyclopropylmethyl phosphate1. It is also quite useful to for stereoselective synthesis of cycloalkene-fused butyrolactones via cyclopropylcarbinol solvolysis.
Referrence
Marshall, James A., and R. H. Ellison. "Stereoselective synthesis of cycloalkene-fused butyrolactones via cyclopropylcarbinol solvolysis." Journal of Organic Chemistry 40.14(1975):2070-2073.
Chemical Properties
Clear colorless liquid
Uses
Cyclopropanemethanol is used as an organic chemical synthesis intermediate.
Uses
Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
Preparation
The preparation of Cyclopropyl carbinol is as follows:A 1L three-necked flask was charged with 100 g (1mol) of methyl cyclopropanoate. 57g (1.5mol) of sodium borohydride, 500 mL of methanol, and then cooled to 2°C, 66.67g (0.5mol) of aluminum trichloride was added in batches and reacted overnight. The reaction was quenched by the addition of a saturated aqueous solution of ammonium chloride, filtered, and the filtrate was concentrated and evaporated. The product was collected in a yield of 53.49g, a yield of 74.3%.
General Description
Cyclopropanemethanol (Cyclopropyl carbinol, CPMO), a cycloalkanemethanol, is an anaesthetic. The coupling reaction of cyclopropanemethanol with alkynes to form substituted allylic alcohols has been reported. The microwave spectrum of CPMO has been recorded. Its rotational constants and dipole moment have been determined.
Cyclopropyl carbinol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Cyclopropyl carbinol manufacturers
- Product
- Cyclopropyl carbinol 2516-33-8
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26
- Product
- Cyclopropyl carbinol 2516-33-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-07-24
- Product
- Cyclopropanemethanol 2516-33-8
- Price
- US $100.00/KG
- Min. Order
- 25KG
- Purity
- 99.5%min.
- Supply Ability
- 100 tons per year
- Release date
- 2018-04-03