(Bromomethyl)cyclopropane
Uses Description- Product Name
- (Bromomethyl)cyclopropane
- CAS No.
- 7051-34-5
- Chemical Name
- (Bromomethyl)cyclopropane
- Synonyms
- CYCLOPROPYLMETHYL BROMIDE;Cyclopropane, (bromomethyl)-;CPMBr;(Bromomethyl)cyclopr;(Xiu Jiaji)cyclopropane;BroMoMethyl)cyclopropan;Cyclopropylmethylbromid;Roflumilast impurity 18;CYCLOPROPYLMETYL BROMIDE;Bromo(cyclopropyl)methane
- CBNumber
- CB8119915
- Molecular Formula
- C4H7Br
- Formula Weight
- 135
- MOL File
- 7051-34-5.mol
(Bromomethyl)cyclopropane Property
- Melting point:
- 87-90 °C
- Boiling point:
- 105-107 °C(lit.)
- Density
- 1.392 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.457(lit.)
- Flash point:
- 107 °F
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Liquid
- Specific Gravity
- 1.392
- color
- Clear colorless to slightly colored
- Water Solubility
- Not miscible in water.
- BRN
- 605296
- Stability:
- Stable. Flammable. Incompatible with strong bases, strong oxidizing agents.
- InChI
- 1S/C4H7Br/c5-3-4-1-2-4/h4H,1-3H2
- InChIKey
- AEILLAXRDHDKDY-UHFFFAOYSA-N
- SMILES
- BrCC1CC1
- CAS DataBase Reference
- 7051-34-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Cyclopropane, (bromomethyl)-(7051-34-5)
Safety
- Hazard Codes
- Xi,F,Xn
- Risk Statements
- 10-36/37/38-22
- Safety Statements
- 23-24/25-37/39-26-16-36/37/39
- RIDADR
- UN 1993 3/PG 3
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29035990
- Storage Class
- 3 - Flammable liquids
- Hazard Classifications
- Acute Tox. 4 Oral
Flam. Liq. 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H302Harmful if swallowed
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- 242403
- Product name
- (Bromomethyl)cyclopropane
- Purity
- 97%
- Packaging
- 1g
- Price
- $55.7
- Updated
- 2025/07/31
- Product number
- 242403
- Product name
- (Bromomethyl)cyclopropane
- Purity
- 97%
- Packaging
- 5g
- Price
- $167
- Updated
- 2025/07/31
- Product number
- C988725
- Product name
- CyclopropylmethylBromide
- Packaging
- 100g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- C988725
- Product name
- CyclopropylmethylBromide
- Packaging
- 50g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- J91168
- Product name
- Cyclopropylmethylbromide
- Packaging
- 4x25g
- Price
- $90
- Updated
- 2021/12/16
(Bromomethyl)cyclopropane Chemical Properties,Usage,Production
Uses
(Bromomethyl)cyclopropane is used in the synthesis of 1,4-dienes by iron-catalyzed cross-coupling with alkenyl Grignard reagents.
Description
(Bromomethyl) cyclopropane is a cyclopropane derivative. It can be used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1, 4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.
Chemical Properties
Colorless to yellow liquid
Uses
(Bromomethyl)cyclopropane was used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.
Synthesis Reference(s)
Tetrahedron Letters, 13, p. 2135, 1972 DOI: 10.1016/S0040-4039(01)84787-0
General Description
The coupling reaction of (bromomethyl)cyclopropane with phenylmagnesium bromide was studied.
Synthesis
2516-33-8
7051-34-5
Example 1 (control experiment): 1250 mL of dimethylformamide (DMF) was added to the reaction vessel under nitrogen protection, followed by 280.8 g of triphenylphosphine. 70 g of hydroxymethylcyclopropane was added with stirring and the reaction was carried out at room temperature for 30 minutes. After cooling the reaction solution to -10°C, 158.3 g of bromine (102% of the theoretical amount) was slowly added dropwise over a period of 4 hours. Upon completion of the reaction, the reaction mixture was purified by distillation to afford bromomethylcyclopropane in 77.5% yield (based on theoretical values) with a product purity of >97%, which contained 0.6% open-chain haloalkanes.
References
[1] Patent: US6008420, 1999, A
[2] Patent: US2016/355452, 2016, A1. Location in patent: Paragraph 0062; 0063
[3] Synthetic Communications, 1996, vol. 26, # 6, p. 1109 - 1115
[4] Journal of the Chemical Society, Chemical Communications, 1982, # 18, p. 1037 - 1039
[5] European Journal of Medicinal Chemistry, 1980, vol. 15, # 6, p. 571 - 573
(Bromomethyl)cyclopropane Preparation Products And Raw materials
Raw materials
Preparation Products
(Bromomethyl)cyclopropane Suppliers
- Tel
- 0519-86889226 18015049226
- Fax
- 18015049226
- jifuzhong01@163.com
- Country
- China
- ProdList
- 41
- Advantage
- 58
- Tel
- 0519-88995800 13815038136
- Fax
- 0519-88995808
- gjf@dcpharmtech.com
- Country
- China
- ProdList
- 62
- Advantage
- 55
- Tel
- 0571-87322520 18957127338
- June@zetchem.com
- Country
- China
- ProdList
- 382
- Advantage
- 58
- Tel
- 0519-86627600 13775194445
- xwz@eastfine.net
- Country
- China
- ProdList
- 18
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
View Lastest Price from (Bromomethyl)cyclopropane manufacturers
- Product
- (Bromomethyl)cyclopropane 7051-34-5
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-06
- Product
- (Bromomethyl)cyclopropane 7051-34-5
- Price
- US $20.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200 tons/ year
- Release date
- 2020-03-11
- Product
- (Bromomethyl)cyclopropane 7051-34-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100tons
- Release date
- 2023-09-27