SULFISOXAZOLE ACETYL (200 MG)

Product Name: SULFISOXAZOLE ACETYL (200 MG)
CAS No.: 80-74-0
Chemical Name: SULFISOXAZOLE ACETYL (200 MG)
Synonyms: ASIZ;Lipo Gantrisin;acetylsulfafurazole;Gantrisin Pediatric;Sulfisoxazole Acetyl;Acetyl sulfisoxazole;N1-Acetylsulfisoxazole;SULFISOXAZOLE ACETYL (200 MG);Sulfisoxazole Acetyl (1639003);1-(oxazol-2-ylsulfinyl)ethanone
CBNumber: CB6500542
Molecular Formula: C13H15N3O4S
Formula Weight: 309.3409
MOL File: 80-74-0.mol

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SULFISOXAZOLE ACETYL (200 MG) Property

Melting point:: 193-194°
Boiling point:: 538.1±60.0 °C(Predicted)
Density: 1.3541 (rough estimate)
refractive index: 1.6320 (estimate)
pka: -0.17±0.10(Predicted)
form: Solid
color: White to off-white
Water Solubility: 80mg/L(37 ºC)

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Safety

HS Code: 2935904000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1639003
Product name: N-[(4-Aminophenyl)sulfonyl]-N-(3,4-dimethyl-5-isoxazolyl)acetamide
Packaging: 200mg
Price: $280
Updated: 2024/03/01

TRC

Product number: S689225
Product name: SulfisoxazoleAcetyl
Packaging: 100mg
Price: $130
Updated: 2021/12/16

TRC

Product number: S689225
Product name: SulfisoxazoleAcetyl
Packaging: 200mg
Price: $200
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 61837
Product name: SulfisoxazoleAcetyl
Packaging: 100mg
Price: $625
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 61837
Product name: SulfisoxazoleAcetyl
Packaging: 1g
Price: $1275
Updated: 2021/12/16

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SULFISOXAZOLE ACETYL (200 MG) Chemical Properties,Usage,Production

Originator

Gantrisin Acetyl ,Roche ,US ,1954

Uses

Sulfisoxazole Acetyl is an antibiotic used in the prevention of infection especially when used in conjunction with erythromycin.

Uses

Antibacterial.

Definition

ChEBI: Sulfisoxazole acetyl is a sulfonamide and a member of benzenes.

Manufacturing Process

267 grams (1 mol) of sulfisoxazole were suspended in 400 ml of acetone and 79 grams (1 mol) of dry pyridine at 20-25°C in a round-bottom flask equipped with a stirrer and thermometer. 132 grams (1 mol) of acetic anhydride were added within 3 minutes with stirring. The sulfisoxazole dissolved in the mixture and a clear solution resulted. The temperature rose to 39-40°C. After stirring for several minutes, the product started to crystallize as a white crystalline mush. The temperature rose to 42-43°C maintained itself at this temperature for 15-30 minutes, and then started to drop. Stirring was continued for 5 hours and the mixture was then allowed to stand for 10 hours. One liter of 2.5-3.0% ice-cold aqueous ammonia and some fresh ice were then added while stirring and the crystals were filtered without delay. The crystals were washed on the filter with 1 liter of ice-cold 1% ammonia and then with 1 liter of water. The material on the filter was well pressed off, washed with 200-300 ml of alcohol and dried at 70°C to constant weight. The N-monoacetyl sulfisoxazole melted at 193-194°C and showed a positive Bratton-Marshall reaction and a positive Hucknall-Turfat reaction.
The product is in the form of colorless crystals which are somewhat water repellent. It is insoluble in alkali but is saponified upon standing in alkaline suspension (3% ammonia). It is soluble in strong acids (20-36% HCl or 10 N H2SO4) and is rapidly saponified upon standing.

brand name

Gantrisin (Roche).

Therapeutic Function

Antimicrobial

General Description

Sulfisoxazole acetyl shares the actions and usesof the parent compound, sulfisoxazole. The acetyl derivativeis tasteless and, therefore, suitable for oral administration, especiallyin liquid preparations. The acetyl compound is splitin the intestinal tract and absorbed as sulfisoxazole; that is, itis a prodrug for sulfisoxazole.

SULFISOXAZOLE ACETYL (200 MG) Preparation Products And Raw materials

Raw materials

Acetylsulfonamide Isoxazole Anhydrous pyridine

Preparation Products

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SULFISOXAZOLE ACETYL (200 MG) Suppliers

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View Lastest Price from SULFISOXAZOLE ACETYL (200 MG) manufacturers

Dideu Industries Group Limited

Product: SULFISOXAZOLE ACETYL (200 MG) 80-74-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-14

80-74-0, SULFISOXAZOLE ACETYL (200 MG)Related Search:

Toluidine Blue O Isoxazole Sulfisoxazole 4-AMINO-N,N-DIMETHYL-BENZENESULFONAMIDE 5-AMINO-3-METHYLISOXAZOLE Sulfacetamide 4-AMINO-N-ETHYL-BENZENESULFONAMIDE isoxazol-5-amine 3,4-Dimethylisoxazol-5-amine SULFISOXAZOLE ACETYL (200 MG)

SULFISOXAZOLE ACETYL (200 MG)

Acetamide, N-[(4-aminophenyl)sulfonyl]-N-(3,4-dimethyl-5-isoxazolyl)-

Acetyl sulfisoxazole

Lipo Gantrisin

N-(3,4-Dimethyl-5-isoxazolyl)-N-sulfanilylacetamide

n-3,4-dimethylisoxazol-5-yl-n-sulfanilylacetamide

N-Acetyl-4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide

Sulfisoxazole Acetyl

N-3,4-dimethylisoxazol-5-yl-N-sulphanilylacetamide

acetylsulfafurazole

5-[N-Acetyl-N-(p-aminophenylsulfonyl)amino]-3,4-dimethylisoxazole

N-(4-Aminophenylsulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)acetamide

N-(4-aminophenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)acetamide

N-(4-aminophenyl)sulfonyl-N-(3,4-dimethylisoxazol-5-yl)acetamide

N-(4-azanylphenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)ethanamide

1-(oxazol-2-ylsulfinyl)ethanone

N1-Acetylsulfisoxazole

ASIZ

SULFISOXAZOLE ACETYL (200 MG) USP/EP/BP

Sulfisoxazole Acetyl (1639003)

Gantrisin Pediatric

Inhibitor,antibacterial action,N1-Acetylsulfisoxazole,inhibit,Bacterial,Sulfisoxazole acetyl,Sulfisoxazole derivative,orally active,dihydropteroate synthase

80-74-0