SULFISOXAZOLE ACETYL (200 MG)
- Product Name
- SULFISOXAZOLE ACETYL (200 MG)
- CAS No.
- 80-74-0
- Chemical Name
- SULFISOXAZOLE ACETYL (200 MG)
- Synonyms
- ASIZ;Lipo Gantrisin;acetylsulfafurazole;Gantrisin Pediatric;Sulfisoxazole Acetyl;Acetyl sulfisoxazole;N1-Acetylsulfisoxazole;SULFISOXAZOLE ACETYL (200 MG);Sulfisoxazole Acetyl (1639003);1-(oxazol-2-ylsulfinyl)ethanone
- CBNumber
- CB6500542
- Molecular Formula
- C13H15N3O4S
- Formula Weight
- 309.3409
- MOL File
- 80-74-0.mol
SULFISOXAZOLE ACETYL (200 MG) Property
- Melting point:
- 193-194°
- Boiling point:
- 538.1±60.0 °C(Predicted)
- Density
- 1.3541 (rough estimate)
- refractive index
- 1.6320 (estimate)
- pka
- -0.17±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- Water Solubility
- 80mg/L(37 ºC)
Safety
- HS Code
- 2935904000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 1639003
- Product name
- N-[(4-Aminophenyl)sulfonyl]-N-(3,4-dimethyl-5-isoxazolyl)acetamide
- Packaging
- 200mg
- Price
- $261
- Updated
- 2025/07/31
- Product number
- S689225
- Product name
- SulfisoxazoleAcetyl
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- S689225
- Product name
- SulfisoxazoleAcetyl
- Packaging
- 200mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 61837
- Product name
- SulfisoxazoleAcetyl
- Packaging
- 100mg
- Price
- $625
- Updated
- 2021/12/16
- Product number
- 61837
- Product name
- SulfisoxazoleAcetyl
- Packaging
- 1g
- Price
- $1275
- Updated
- 2021/12/16
SULFISOXAZOLE ACETYL (200 MG) Chemical Properties,Usage,Production
Chemical Properties
Crystals. Melting point 192-195°C. Solubility (mg/ml) at 25°C: 0.07 in water, 4.93 in methanol, 5.7 in 95% ethanol, 29.0 in chloroform.
Originator
Gantrisin Acetyl ,Roche ,US ,1954
Uses
Sulfisoxazole Acetyl is an antibiotic used in the prevention of infection especially when used in conjunction with erythromycin.
Uses
Antibacterial.
Definition
ChEBI: Sulfisoxazole acetyl is a sulfonamide and a member of benzenes.
Manufacturing Process
267 grams (1 mol) of sulfisoxazole were suspended in 400 ml of acetone and
79 grams (1 mol) of dry pyridine at 20-25°C in a round-bottom flask equipped
with a stirrer and thermometer. 132 grams (1 mol) of acetic anhydride were
added within 3 minutes with stirring. The sulfisoxazole dissolved in the
mixture and a clear solution resulted. The temperature rose to 39-40°C. After
stirring for several minutes, the product started to crystallize as a white
crystalline mush. The temperature rose to 42-43°C maintained itself at this
temperature for 15-30 minutes, and then started to drop. Stirring was
continued for 5 hours and the mixture was then allowed to stand for 10 hours.
One liter of 2.5-3.0% ice-cold aqueous ammonia and some fresh ice were
then added while stirring and the crystals were filtered without delay. The
crystals were washed on the filter with 1 liter of ice-cold 1% ammonia and
then with 1 liter of water. The material on the filter was well pressed off,
washed with 200-300 ml of alcohol and dried at 70°C to constant weight. The
N-monoacetyl sulfisoxazole melted at 193-194°C and showed a positive
Bratton-Marshall reaction and a positive Hucknall-Turfat reaction.
The product is in the form of colorless crystals which are somewhat water
repellent. It is insoluble in alkali but is saponified upon standing in alkaline
suspension (3% ammonia). It is soluble in strong acids (20-36% HCl or 10 N
H2SO4) and is rapidly saponified upon standing.
brand name
Gantrisin (Roche).
Therapeutic Function
Antimicrobial
General Description
Sulfisoxazole acetyl shares the actions and usesof the parent compound, sulfisoxazole. The acetyl derivativeis tasteless and, therefore, suitable for oral administration, especiallyin liquid preparations. The acetyl compound is splitin the intestinal tract and absorbed as sulfisoxazole; that is, itis a prodrug for sulfisoxazole.
SULFISOXAZOLE ACETYL (200 MG) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SULFISOXAZOLE ACETYL (200 MG) manufacturers
- Product
- SULFISOXAZOLE ACETYL (200 MG) 80-74-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-14