3,4-Dimethylisoxazol-5-amine

Product Name: 3,4-Dimethylisoxazol-5-amine
CAS No.: 19947-75-2
Chemical Name: 3,4-Dimethylisoxazol-5-amine
Synonyms: 5-AMino-3;NSC 143787;4-diMethylisoxazole;5-Amino-3,4-dimethyL;3,4-Dimethyl-5-isoxazolamine;3,4-DIMETHYLISOXAZOL-5-AMINE;5-AMINO-3,4-DIMETHYLISOXAZOLE;3,4-DiMethyl-5-isoxazolylaMine;5-Amino-3,4-dimethylisooxazole;3,4-dimethylisoxazol-5-ylamine
CBNumber: CB2389240
Molecular Formula: C5H8N2O
Formula Weight: 112.13
MOL File: 19947-75-2.mol

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3,4-Dimethylisoxazol-5-amine Property

Melting point:: 118-122 °C(lit.)
Boiling point:: 246.0±35.0 °C(Predicted)
Density: 1.118±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO, Methanol
pka: -0.24±0.50(Predicted)
form: Solid
color: White to Off-White
BRN: 108546
InChI: InChI=1S/C5H8N2O/c1-3-4(2)7-8-5(3)6/h6H2,1-2H3
InChIKey: PYNDWPFZDQONDV-UHFFFAOYSA-N
SMILES: O1C(N)=C(C)C(C)=N1
CAS DataBase Reference: 19947-75-2(CAS DataBase Reference)
NIST Chemistry Reference: 5-Amino-3,4-dimethyl-isoxazole(19947-75-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3179
Product name: 5-Amino-3,4-dimethylisoxazole
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $143
Updated: 2025/07/31

TCI Chemical

Product number: A3179
Product name: 5-Amino-3,4-dimethylisoxazole
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $505
Updated: 2025/07/31

TRC

Product number: A606835
Product name: 5-Amino-3,4-dimethylisoxazole
Packaging: 10g
Price: $90
Updated: 2021/12/16

Usbiological

Product number: 002520
Product name: 5-Amino-3
Packaging: 5mg
Price: $425
Updated: 2021/12/16

Usbiological

Product number: A1379-12
Product name: 5-Amino-3-
Packaging: 10mg
Price: $460
Updated: 2021/12/16

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3,4-Dimethylisoxazol-5-amine Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Cyrstalline Solid

General Description

5-amino-3,4-dimethylisoxazole formed complexes with cobalt(II) and copper(II). The kinetics of gas-phase thermal isomerization of 5-amino-3,4-dimethylisoxazole was studied.

Synthesis

4468-47-7

19947-75-2

General procedure for the synthesis of 3,4-dimethylisoxazol-5-amine using 2-methyl-3-oxobutanenitrile as starting material: 2-methyl-3-oxobutanenitrile (9.7 g, 0.1 mol), hydroxylamine hydrochloride (7 g, 0.1 mol), and water (20 mL) were mixed, followed by the slow dropwise addition of NaOH aqueous solution (4 g dissolved in 10 mL of water) at 40 °C. After the dropwise addition, the reaction mixture was heated to reflux for 3 hours. After completion of the reaction, it was cooled to room temperature and phase separation was carried out. After the organic layer was allowed to stand overnight, filtration afforded the white crystalline product 3,4-dimethylisoxazol-5-amine (3.66 g, yield 32.7%) with a melting point of 123-125 °C.

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 15, p. 4661 - 4667
[2] Pharmaceutical bulletin, 1954, vol. 2, # 1, p. 62 - 64
[3] Yakugaku Zasshi, 1951, vol. 71, p. 1356,1358
[4] Chem.Abstr., 1952, p. 8036
[5] Yakugaku Zasshi, 1951, vol. 71, p. 1356,1358

3,4-Dimethylisoxazol-5-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,4-Dimethylisoxazol-5-amine Suppliers

Americas 1 Belgium 1 Canada 1 China 84 Europe 1 France 1 Germany 4 India 5 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 9 United States 24 Global 134

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View Lastest Price from 3,4-Dimethylisoxazol-5-amine manufacturers

Career Henan Chemical Co

Product: 3,4-Dimethylisoxazol-5-amine 19947-75-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

19947-75-2, 3,4-Dimethylisoxazol-5-amineRelated Search:

Dimethyl phthalate ETHANE Dimethyl ether Dibenzylamine Triallylamine N,N-Dimethylformamide Dimethyl sulfoxide Dimethyl sulfate Isoxazole Dacthal Bis(2-ethylhexyl)amine Dimethyl fumarate Lithium diisopropylamide Triethanolamine Dimethyl carbonate Poly(dimethylsiloxane) Sulfisoxazole 3,5-dimethylisoxazol-4-amine

5-AMINO-3,4-DIMETHYLISOXAZOLE

3,4-DIMETHYLISOXAZOL-5-AMINE

5-Isoxazolamine, 3,4-dimethyl-

3,4-dimethylisoxazol-5-ylamine

3,4-Dimethyl-5-isoxazolamine

5-Amino-3,4-dimethylisooxazole

4-diMethylisoxazole

5-AMino-3

3,4-DiMethyl-5-isoxazolylaMine

NSC 143787

5-Amino-3,4-dimethylisoxazole 97%

3,4-dimethyl-1,2-oxazol-5-amine

5-Amino-3,4-dimethyL

19947-75-2

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