3,5-Dimethyl-4-isoxazolamine
- Product Name
- 3,5-Dimethyl-4-isoxazolamine
- CAS No.
- 31329-64-3
- Chemical Name
- 3,5-Dimethyl-4-isoxazolamine
- Synonyms
- AKOS B020738;TIMTEC-BB SBB005896;ART-CHEM-BB B020738;3,5-dimethylisoxazol-4-amine;3,5-DIMETHYL-4-ISOXAZOLAMINE;3,5-Dimethylisoxazole-4-amine;4-AMINO-3,5-DIMETHYLISOXAZOLE;4-Isoxazolamine, 3,5-dimethyl-;3,5-DIMETHYL-ISOXAZOL-4-YLAMINE;4-AMino-3,5-diMethylisoxazole 97%
- CBNumber
- CB5768143
- Molecular Formula
- C5H8N2O
- Formula Weight
- 112.13
- MOL File
- 31329-64-3.mol
3,5-Dimethyl-4-isoxazolamine Property
- Melting point:
- 41-46 °C(lit.)
- Boiling point:
- 78-80°C 0,4mm
- Density
- 1.118±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 1.59±0.10(Predicted)
- form
- solid
- Appearance
- Light yellow to yellow Solid
- CAS DataBase Reference
- 31329-64-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 575069
- Product name
- 4-Amino-3,5-dimethylisoxazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $290
- Updated
- 2023/06/20
- Product number
- 575069
- Product name
- 4-Amino-3,5-dimethylisoxazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $143
- Updated
- 2023/01/07
- Product number
- D474395
- Product name
- 3,5-Dimethylisoxazol-4-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- D474395
- Product name
- 3,5-Dimethylisoxazol-4-amine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA71694
- Product name
- 4-Amino-3,5-dimethylisoxazole
- Packaging
- 2g
- Price
- $40
- Updated
- 2021/12/16
3,5-Dimethyl-4-isoxazolamine Chemical Properties,Usage,Production
Uses
4-Amino-3,5-dimethylisoxazole may be used in the synthesis of 3,5-dimethyl-4-phenylazoisoxazole via reaction with nitrosobenzene.The diazonium salt of 4-Amino-3,5-dimethylisoxazole can react with cupric sulfate to form acetyltriazole derivatives.
General Description
4-Amino-3,5-dimethylisoxazole can be prepared via reduction of 3,5-dimethyl-4-nitroisoxazole in the presence of Zn/NH4Cl in H2O.
Synthesis
1123-49-5
31329-64-3
Step A Synthesis of 3,5-dimethylisoxazol-4-amine: 12.00 g (84.44 mmol) of 3,5-dimethyl-4-nitroisoxazole was dissolved in 430 ml of water and 106.15 g (1.984 mol) of ammonium chloride was added. At 4°C, 46.93 g (7.17 mol) of zinc powder was added in batches over a period of 2 hours. Upon completion of the reaction, ethyl acetate was added to the reaction mixture for extraction and the organic phase was filtered through diatomaceous earth to remove solid impurities. The organic layer was dried with anhydrous magnesium sulfate and the solvent was removed by distillation under reduced pressure to afford 3,5-dimethylisoxazol-4-amine in 86% (8.10 g) yield. The product was characterized by 1H-NMR (300 MHz, CDCl3): δ= 2.20 (s, 3H) ppm; 2.28 (s, 3H) ppm; 2.51 (wide s, 2H) ppm.
References
[1] Helvetica Chimica Acta, 1991, vol. 74, # 3, p. 531 - 542
[2] Journal of the Chemical Society, 1921, vol. 119, p. 702
[3] Gazzetta Chimica Italiana, 1941, vol. 71, p. 327,336
[4] Patent: US2003/187028, 2003, A1
[5] Patent: US2002/82264, 2002, A1
3,5-Dimethyl-4-isoxazolamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Dimethyl-4-isoxazolamine manufacturers
- Product
- 3,5-Dimethyl-4-isoxazolamine 31329-64-3
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-20
- Product
- 3,5-Dimethyl-4-isoxazolamine 31329-64-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-22