ChemicalBook > CAS DataBase List > 3,5-Dimethyl-4-isoxazolamine

3,5-Dimethyl-4-isoxazolamine

Product Name
3,5-Dimethyl-4-isoxazolamine
CAS No.
31329-64-3
Chemical Name
3,5-Dimethyl-4-isoxazolamine
Synonyms
AKOS B020738;TIMTEC-BB SBB005896;ART-CHEM-BB B020738;3,5-dimethylisoxazol-4-amine;3,5-DIMETHYL-4-ISOXAZOLAMINE;3,5-Dimethylisoxazole-4-amine;4-AMINO-3,5-DIMETHYLISOXAZOLE;4-Isoxazolamine, 3,5-dimethyl-;3,5-DIMETHYL-ISOXAZOL-4-YLAMINE;4-AMino-3,5-diMethylisoxazole 97%
CBNumber
CB5768143
Molecular Formula
C5H8N2O
Formula Weight
112.13
MOL File
31329-64-3.mol
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3,5-Dimethyl-4-isoxazolamine Property

Melting point:
41-46 °C(lit.)
Boiling point:
78-80°C 0,4mm
Density 
1.118±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
1.59±0.10(Predicted)
form 
solid
Appearance
Light yellow to yellow Solid
CAS DataBase Reference
31329-64-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
575069
Product name
4-Amino-3,5-dimethylisoxazole
Purity
97%
Packaging
5g
Price
$290
Updated
2023/06/20
Sigma-Aldrich
Product number
575069
Product name
4-Amino-3,5-dimethylisoxazole
Purity
97%
Packaging
1g
Price
$143
Updated
2023/01/07
TRC
Product number
D474395
Product name
3,5-Dimethylisoxazol-4-amine
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
D474395
Product name
3,5-Dimethylisoxazol-4-amine
Packaging
500mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
4H30-1-Z8
Product name
4-Amino-3,5-dimethylisoxazole
Packaging
1g
Price
$75
Updated
2021/12/16
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3,5-Dimethyl-4-isoxazolamine Chemical Properties,Usage,Production

Uses

4-Amino-3,5-dimethylisoxazole may be used in the synthesis of 3,5-dimethyl-4-phenylazoisoxazole via reaction with nitrosobenzene.The diazonium salt of 4-Amino-3,5-dimethylisoxazole can react with cupric sulfate to form acetyltriazole derivatives.

General Description

4-Amino-3,5-dimethylisoxazole can be prepared via reduction of 3,5-dimethyl-4-nitroisoxazole in the presence of Zn/NH4Cl in H2O.

Synthesis

1123-49-5

31329-64-3

Step A Synthesis of 3,5-dimethylisoxazol-4-amine: 12.00 g (84.44 mmol) of 3,5-dimethyl-4-nitroisoxazole was dissolved in 430 ml of water and 106.15 g (1.984 mol) of ammonium chloride was added. At 4°C, 46.93 g (7.17 mol) of zinc powder was added in batches over a period of 2 hours. Upon completion of the reaction, ethyl acetate was added to the reaction mixture for extraction and the organic phase was filtered through diatomaceous earth to remove solid impurities. The organic layer was dried with anhydrous magnesium sulfate and the solvent was removed by distillation under reduced pressure to afford 3,5-dimethylisoxazol-4-amine in 86% (8.10 g) yield. The product was characterized by 1H-NMR (300 MHz, CDCl3): δ= 2.20 (s, 3H) ppm; 2.28 (s, 3H) ppm; 2.51 (wide s, 2H) ppm.

References

[1] Helvetica Chimica Acta, 1991, vol. 74, # 3, p. 531 - 542
[2] Journal of the Chemical Society, 1921, vol. 119, p. 702
[3] Gazzetta Chimica Italiana, 1941, vol. 71, p. 327,336
[4] Patent: US2003/187028, 2003, A1
[5] Patent: US2002/82264, 2002, A1

3,5-Dimethyl-4-isoxazolamine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3,5-Dimethyl-4-isoxazolamine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3,5-Dimethyl-4-isoxazolamine 31329-64-3
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-20
Career Henan Chemical Co
Product
3,5-Dimethyl-4-isoxazolamine 31329-64-3
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22

31329-64-3, 3,5-Dimethyl-4-isoxazolamineRelated Search:

3,5-Dimethylisoxazole Sulfamethoxazole N,N-Dimethylformamide Glycine Dimethyl phthalate Dimethyl sulfide Isoxazole ISOXAFLUTOLE Dimethyl fumarate Dimethyl sulfoxide Dimethyl ether Sulfisoxazole ALTRENOGEST ETHANE N,N-Dimethyl-1,4-phenylenediamine Betaine 3,5-DIMETHYLISOXAZOL-4-YL ISOCYANATE N,N'-BIS(5-METHYL-3-PHENYL-4-ISOXAZOLYL)UREA

  • TIMTEC-BB SBB005896
  • AKOS B020738
  • 3,5-DIMETHYL-4-ISOXAZOLAMINE
  • 3,5-DIMETHYL-ISOXAZOL-4-YLAMINE
  • 4-AMINO-3,5-DIMETHYLISOXAZOLE
  • ART-CHEM-BB B020738
  • 3,5-dimethylisoxazol-4-amine
  • 3,5-Dimethylisoxazole-4-amine
  • 4-AMino-3,5-diMethylisoxazole 97%
  • 4-Isoxazolamine, 3,5-dimethyl-
  • 31329-64-3
  • ARYL AMINE
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  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Amines
  • Oxazoles, Isoxazoles & Benzoxazoles
  • Oxazole&Isoxazole
  • Oxazoles, Isoxazoles & Benzoxazoles
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