3-Bromo-2-methoxybenzoic acid
- Product Name
- 3-Bromo-2-methoxybenzoic acid
- CAS No.
- 101084-39-3
- Chemical Name
- 3-Bromo-2-methoxybenzoic acid
- Synonyms
- 3-Bromo-o-anisic Acid;3-BROMO-2-METHOXYBENZOIC;3-BROMO-2-METHOXYBENZOIC ACID;3-BROMO-2-METHOXYBENZOIC ACID 97;Benzoic acid, 3-bromo-2-methoxy-;3-Bromo-2-methoxybenzoic acid 97%;Ethanone,2-bromo-1-[5-(trifluoromethyl)phenyl]-
- CBNumber
- CB6501307
- Molecular Formula
- C8H7BrO3
- Formula Weight
- 231.04
- MOL File
- 101084-39-3.mol
3-Bromo-2-methoxybenzoic acid Property
- Melting point:
- 119-123 °C
- Boiling point:
- 327.6±27.0 °C(Predicted)
- Density
- 1.625±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.70±0.10(Predicted)
- color
- White to Light yellow
N-Bromosuccinimide Price
- Product number
- 694436
- Product name
- 3-Bromo-2-methoxybenzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $61.3
- Updated
- 2023/06/20
- Product number
- B5262
- Product name
- 3-Bromo-2-methoxybenzoic Acid
- Packaging
- 1G
- Price
- $27
- Updated
- 2025/07/31
- Product number
- B5262
- Product name
- 3-Bromo-2-methoxybenzoic Acid
- Packaging
- 5G
- Price
- $82
- Updated
- 2025/07/31
- Product number
- OR3358
- Product name
- 3-Bromo-2-methoxybenzoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $113
- Updated
- 2021/12/16
- Product number
- 2621-9-X8
- Product name
- 3-Bromo-2-methoxybenzoic acid
- Purity
- 97%
- Packaging
- 5G
- Price
- $133
- Updated
- 2021/12/16
3-Bromo-2-methoxybenzoic acid Chemical Properties,Usage,Production
Uses
3-Bromo-2-methoxybenzoic Acid is a reactant that has been used in the preparation of biphenylic carboxamides as potent and selective CB2 receptor ligands.
Synthesis
3883-95-2
77-78-1
101084-39-3
General procedure for the synthesis of 3-bromo-2-methoxybenzoic acid from 3-bromo-2-hydroxybenzoic acid (360 g, 1.65 mol) and dimethyl sulfate (443 g, 3.50 mol): 3-bromo-2-hydroxybenzoic acid was added to a reaction vessel and acetone (1.8 L) was added as a solvent. Subsequently, anhydrous potassium carbonate (552 g, 4.0 mol) was added to the reaction system and dimethyl sulfate was added slowly and dropwise. The reaction mixture was carried out under reflux conditions until thin layer chromatography (TLC) showed the disappearance of the raw material. After completion of the reaction, the solid phase was washed with acetone, the organic phases were combined and concentrated. The concentrate was diluted with ethyl acetate, washed sequentially with water and saturated brine and finally dried with anhydrous sodium sulfate. The dried organic phase was filtered and concentrated to afford the target product 3-bromo-2-methoxybenzoic acid (355 g, 94% yield), which can be used directly in the next step of the reaction.
References
[1] Patent: CN106565625, 2017, A. Location in patent: Paragraph 0045-0046
[2] Journal of the Chemical Society, 1923, vol. 123, p. 1992
3-Bromo-2-methoxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-2-methoxybenzoic acid Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 3-Bromo-2-methoxybenzoic acid manufacturers
- Product
- 3-Bromo-2-methoxybenzoic acid 101084-39-3
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-06
- Product
- 3-Bromo-2-methoxybenzoic acid 101084-39-3
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-05