RAN antibody
Source Reactivity Background References- Product Name
- RAN antibody
- Chemical Name
- RAN antibody
- Synonyms
- RAN antibody;Mouse Monoclonal RAN Antibody
- CBNumber
- CB65688607
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb100472
- Product name
- Ran antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb76794
- Product name
- Ran antibody
- Packaging
- 0.1ml
- Price
- $601.8
- Updated
- 2021/12/16
- Product number
- orb100472
- Product name
- Ran antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
RAN antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Hamster;Monkey;Bovine
Background
Ran is a small GTPase of the Ras family that plays a central role in the spacial and temperal organization of eukaryotic cells. During interphase, Ran-GDP localizes to the cytoplasm and Ran-GTP to the nucleus. This polarized localization of Ran ensures its role in nuclear transport. During mitosis, Ran-GTP is chromatin associated, where it promotes spindle assembly and nuclear envolope formation. In S phase, Ran-GTP associates with and inhibits MCM helicase, ensuring precise chromosomal DNA duplication during the cell cycle.
References
[1] Quimby, B.B. and Dasso, M. (2003) Curr. Opin. Cell Biol. 15, 338-344.
[2] Hetzer, M. et al. (2002) Nat. Cell Biol. 4, 177-184.
[3] Yamaguchi, R. and Newport, J. (2003) Cell 113, 115-125.
RAN antibody Preparation Products And Raw materials
Raw materials
Preparation Products
RAN antibody Suppliers
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