tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

Product Name: tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
CAS No.: 2375541-45-8
Chemical Name: tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Synonyms: 187407;Autogramin-2;Autogramin-2, 10 mM in DMSO;Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2;tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester
CBNumber: CB65708228
Molecular Formula: C21H27N3O4S
Formula Weight: 417.52
MOL File: 2375541-45-8.mol

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tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Property

Density: 1.252±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (up t0 25 mg/ml) or in Ethanol (up to 25 mg/ml)
form: solid
pka: 7.59±0.20(Predicted)
color: Off-white
Stability:: Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: BA171490
Product name: Autogramin 2
Packaging: 5mg
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BA171490
Product name: Autogramin 2
Packaging: 10mg
Price: $135
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BA171490
Product name: Autogramin 2
Packaging: 25mg
Price: $287.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BA171490
Product name: Autogramin 2
Packaging: 50mg
Price: $472.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BA171490
Product name: Autogramin 2
Packaging: 100mg
Price: $700
Updated: 2021/12/16

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tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Chemical Properties,Usage,Production

Description

Autogramin-2 (2375541-45-8) is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A).? Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.

References

References/Citations:

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Suppliers

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2375541-45-8, tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylateRelated Search:

3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide Dequalinium chloride NORFLUOXETINE HYDROCHLORIDE DO264 TERT-BUTYL 2-(6-CHLOROPYRIDIN-3-YL)ETHYLCARBAMATE

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

187407

Autogramin-2

Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester

Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2

Autogramin-2, 10 mM in DMSO

2375541-45-8