tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
- Product Name
- tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
- CAS No.
- 2375541-45-8
- Chemical Name
- tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
- Synonyms
- 187407;Autogramin-2;Autogramin-2, 10 mM in DMSO;Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2;tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester
- CBNumber
- CB65708228
- Molecular Formula
- C21H27N3O4S
- Formula Weight
- 417.52
- MOL File
- 2375541-45-8.mol
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Property
- Density
- 1.252±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up t0 25 mg/ml) or in Ethanol (up to 25 mg/ml)
- form
- solid
- pka
- 7.59±0.20(Predicted)
- color
- Off-white
- Stability:
- Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BA171490
- Product name
- Autogramin 2
- Packaging
- 5mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- BA171490
- Product name
- Autogramin 2
- Packaging
- 10mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- BA171490
- Product name
- Autogramin 2
- Packaging
- 25mg
- Price
- $287.5
- Updated
- 2021/12/16
- Product number
- BA171490
- Product name
- Autogramin 2
- Packaging
- 50mg
- Price
- $472.5
- Updated
- 2021/12/16
- Product number
- BA171490
- Product name
- Autogramin 2
- Packaging
- 100mg
- Price
- $700
- Updated
- 2021/12/16
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Chemical Properties,Usage,Production
Description
Autogramin-2 (2375541-45-8) is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A).? Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.
References
References/Citations:
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Suppliers
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