ChemicalBook > CAS DataBase List > A-3 HYDROCHLORIDE

A-3 HYDROCHLORIDE

Product Name
A-3 HYDROCHLORIDE
CAS No.
78957-85-4
Chemical Name
A-3 HYDROCHLORIDE
Synonyms
A-3;A-3 HYDROCHLORIDE;A-3 hydrochloride ,E2506;A-3 hydrochloride, 10 mM in DMSO;TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE;1-phthalenesulfomide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1)
CBNumber
CB6664789
Molecular Formula
C12H14Cl2N2O2S
Formula Weight
321.22
MOL File
78957-85-4.mol
More
Less

A-3 HYDROCHLORIDE Property

Melting point:
173-176°C
storage temp. 
-20°C
solubility 
DMSO: 24 mg/mL
form 
solid
color 
white
InChI
1S/C12H13ClN2O2S.ClH/c13-11-5-1-4-10-9(11)3-2-6-12(10)18(16,17)15-8-7-14;/h1-6,15H,7-8,14H2;1H
InChIKey
VWAGIWCLJAQLAL-UHFFFAOYSA-N
SMILES
Cl[H].NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2935909099
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A1980
Product name
A3 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$155
Updated
2025/07/31
Sigma-Aldrich
Product number
A1980
Product name
A3 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$550
Updated
2023/06/20
TRC
Product number
A608900
Product name
N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide,Hydrochloride
Packaging
25mg
Price
$175
Updated
2021/12/16
TRC
Product number
A608900
Product name
N-(2-Aminoethyl)-5-chloro-1-naphthalenesulfonamide,Hydrochloride
Packaging
250mg
Price
$1355
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
KIN0000018
Product name
A-3 HYDROCHLORIDE
Purity
95.00%
Packaging
250MG
Price
$1871.1
Updated
2021/12/16
More
Less

A-3 HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C

Biochem/physiol Actions

Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM).

IC 50

CK1: 80 μM (Ki); CK2: 5.1 μM (Ki); PKC: 47 μM (Ki); PKA: 4.3 μM (Ki)

A-3 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

A-3 HYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Raise Chemical Technology Co.,Ltd
Tel
15026594951
Fax
0556-5030632
Email
rs@raise-chem.com
Country
China
ProdList
4621
Advantage
55
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
More
Less

View Lastest Price from A-3 HYDROCHLORIDE manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
A3
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle , 10g/bottle, 100g/bottle
Release date
2024-11-26

78957-85-4, A-3 HYDROCHLORIDERelated Search:


  • A-3 HYDROCHLORIDE
  • A-3
  • TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY
  • N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL
  • N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE
  • N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE
  • N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
  • 1-Naphthalenesulfonamide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1)
  • Calmodulin-dependent kinases,CaMK,inhibit,Casein Kinase,PKC,inhibitor,PKA,A 3 hydrochloride,cAMP,calmodulin,kinase,A-3,MLC-kinase,Calmodulin-dependent protein kinases,Protein kinase C,Protein kinase A,A 3,casein,A3 hydrochloride
  • A-3 hydrochloride, 10 mM in DMSO
  • A-3 hydrochloride ,E2506
  • 1-phthalenesulfomide,N-(2-aminoethyl)-5-chloro-, hydrochloride (1:1)
  • 78957-85-4
  • C12H13ClN2O2SHCl
  • C12H13ClN2O2SClH
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Casein Kinase (CK)
  • Serine/Threonine Kinase Inhibitors
  • Kinase/Phosphatase Biology
  • Protein Kinase Inhibitors and Activators
  • Protein Kinase