DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Property

Boiling point:

146-149 °C14 mm Hg(lit.)

Density 

1.052 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.430(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

Chloroform, Dichloromethane

form 

Oil

color 

Colourless

Water Solubility 

Soluble in chloroform and dichloromethane. Not miscible or difficult to mix in water.

Sensitive 

Moisture Sensitive

BRN 

1785614

CAS DataBase Reference

7598-61-0(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

F 

21

HS Code 

29319090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE Chemical Properties,Usage,Production

Chemical Properties

Colourless Oil

Uses

Diethyl 2,2-diethoxyethylphosphonate is used reactant for synthesis of α,β-alkenal derivatives by two-carbon homologation, lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions, α-Phosphovinyl radicals via a radical trapping sequence, inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions and for Friedel-Crafts reactions.

Uses

Reactant for synthesis of:

• α,β-Alkenal derivatives by two-carbon homologation
• Lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions
• α-Phosphovinyl radicals via a radical trapping sequence
• Inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions

Uses

Diethyl 2,2-diethoxyethylphosphonate can be used as a useful wittig reagent.