2,4-Thiazolidinedione

Product Name: 2,4-Thiazolidinedione
CAS No.: 2295-31-0
Chemical Name: 2,4-Thiazolidinedione
Synonyms: THIAZOLIDINE-2,4-DIONE;TZD;Thiazolidinedione;2,4-Thiazolidindione;U 25560;idinedione;usafek-5496;2,4-ThiazoL;USAF ek-5496;AURORA 23272
CBNumber: CB6675365
Molecular Formula: C3H3NO2S
Formula Weight: 117.13
MOL File: 2295-31-0.mol

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2,4-Thiazolidinedione Property

Melting point:: 125-127 °C (lit.)
Boiling point:: 178-179 °C (19 mmHg)
Density: 1.408 (estimate)
vapor pressure: 0Pa at 25℃
refractive index: 1.5130 (estimate)
Flash point:: 178-179°C/19mm
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Crystalline Powder
pka: 6.50±0.10(Predicted)
color: Slightly yellow
Water Solubility: Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.
BRN: 110700
InChIKey: ZOBPZXTWZATXDG-UHFFFAOYSA-N
LogP: -0.29 at 25℃
CAS DataBase Reference: 2295-31-0(CAS DataBase Reference)
NIST Chemistry Reference: 2,4-Thiazolidinedione(2295-31-0)
EPA Substance Registry System: 2,4-Thiazolidinedione (2295-31-0)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
RTECS: XJ5775000
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29341000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 375004
Product name: 2,4-Thiazolidinedione
Purity: technical grade, 90%
Packaging: 25g
Price: $79
Updated: 2024/03/01

Sigma-Aldrich

Product number: 375004
Product name: 2,4-Thiazolidinedione
Purity: technical grade, 90%
Packaging: 100g
Price: $123
Updated: 2024/03/01

TCI Chemical

Product number: T1990
Product name: 2,4-Thiazolidinedione
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $19
Updated: 2024/03/01

TCI Chemical

Product number: T1990
Product name: 2,4-Thiazolidinedione
Purity: >98.0%(GC)(T)
Packaging: 100g
Price: $51
Updated: 2024/03/01

Alfa Aesar

Product number: A13496
Product name: 2,4-Thiazolidinedione, 99%
Packaging: 25g
Price: $59.65
Updated: 2024/03/01

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2,4-Thiazolidinedione Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Powder

Uses

Inhibitor of enzyme

Uses

2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.

Definition

ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.

General Description

2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.

Flammability and Explosibility

Not classified

2,4-Thiazolidinedione Preparation Products And Raw materials

Raw materials

Preparation Products

Thiazole-5-carboxaldehyde Thiazole-4-carboxaldehyde Rosiglitazone

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2,4-Thiazolidinedione Suppliers

Austria 2 Belgium 1 Canada 6 China 407 Czech 1 Europe 2 France 2 Germany 8 India 73 Japan 8 Russia 1 Slovakia 1 South Korea 2 Switzerland 4 Ukraine 3 United Kingdom 22 United States 54 Global 597

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

BIESTERFELD SPEZIALCHEMIE GMBH

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Email: compliance@biesterfeld.com
Country: Germany
ProdList: 211
Advantage: 58

SYNTHON Chemicals GmbH & Co. KG

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Email: synthon@synthon-chemicals.com
Country: Germany
ProdList: 2000
Advantage: 65

PARAGOS

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Email: info@paragos.com
Country: Germany
ProdList: 6371
Advantage: 39

Service Chemical Inc.

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Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

ABCR GmbH & CO. KG

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Email: info@abcr.de
Country: Germany
ProdList: 6831
Advantage: 75

Merck Schuchardt OHG

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Email: schuchardt-vertrieb@merck.de
Country: Germany
ProdList: 5827
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AKos Consulting & Solutions GmbH

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Email: akos@akosgmbh.de
Country: Germany
ProdList: 6717
Advantage: 72

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View Lastest Price from 2,4-Thiazolidinedione manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: 2,4-Thiazolidinedione 2295-31-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-25

Hebei Yanxi Chemical Co., Ltd.

Product: 2,4-Thiazolidinedione 2295-31-0
Price: US $30.00-10.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-11-17

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2,4-Thiazolidinedione 2295-31-0
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-20

2295-31-0, 2,4-ThiazolidinedioneRelated Search:

Fosthiazate Benzothiazole 2-Methyl-4-isothiazolin-3-one THIAZOLIDINE Thiazole 2,5-Dimethylpyrrolidine Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 5a-Androstanedione N-Methyl-2-pyrrolidone Polyvinylpyrrolidone 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione Pioglitazone hydrochloride 3-ETHYLRHODANINE 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione sodium salt 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione N-Oxide Pioglitazone 2,4-thiazolidinedione,5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1- 2,4-Thiazolidinedione, 2-thio-,2,4-thiazolidinedione,2-thio-[qr

2,4-Thiazolidinedione, 99% 100GR

2,4-Thiazolidinedione, 99% 25GR

thiazolidin-2,4-dione

2,4-Thiazolidinedione technical grade, 90%

2, 4 - Margaret diketone

OTAVA-BB BB7112440002

TZD

TIMTEC-BB SBB000047

THIAZOLIDINE-2,4-DIONE

2,4(3H,5H)-Thiazoledione

2,4-Dioxothiazolidine

Thiazolidinedione

Thiazolidinedione-2,4

USAF ek-5496

usafek-5496

AURORA 23272

2,3,4,5-TETRAHYDROTHIAZOLE-2,4-DIONE

1,3-Thiazolane-2,4-dione

1,3-Thiazolane-2,4-dione, 2,4-Dioxo-1,3-thiazolidine

2,4-ThiazoL

idinedione

1,3-THIAZOLIDINE-2,4-DIONE

2,4-DIKETOTHIAZOLIDINE

2,4-THIAZOLIDINEDIONE

2,4-Thiazolidinedione 、Thiazolidine-2,4-dione

AKOS B029064

2,4-Thiadolidinedione

2,4(3H,5H)-Thiazoledion

U 25560

2,4-Thiazolidinedione ,99%

2,4-Thiazolinedione

2,4-THIAZOLIDINEDIONE, TECH., 90%

2,4-Thiazolidindione

2,4-Thiazolidondione

2,4-Thiozolidinedione

1,3-Thiazolidine-2,4-dione 98%

Thiazoline-2,4-dione(2,4-thiazolidinedion)

2,4-THIAZOLIDINEDIONE 98%

2,4-THIZAOLODINE

2,4-Thiazolidinedione &gt

2,4-Thiazolidinedione (P)

Thiazolidin-2,4-dion

Thiazolidinedione (6CI)

Pioglitazone impurity thiazolidine-2,4-dione

2295-31-0

2295-31-2

C3H3NO2S

C3H2KNO2S

Building Blocks

Heterocyclic Building Blocks

Thiazoles

Thiazolines/Thiazolidines

Starting Raw Materials & Intermediates

PHARMACEUTICAL INTERMEDIATES

Sulphur Derivatives

Sulfur compounds

blocks

Heterocycles