2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine
- Product Name
- 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine
- CAS No.
- 133240-06-9
- Chemical Name
- 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine
- Synonyms
- Adenosine receptor antagonist 4;5,7-DiMethyl-2-ethyliMidazo[4,5-b]pyridine;2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-β]pyridine;2-ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine;2-ETHYL-5,7-DIMETHYL-3H-IMIDAZO[4,5-B]PYRIDINE;3H-Imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl-;1H-IMIDAZO[4,5-B]PYRIDINE, 2-ETHYL-5,7-DIMETHYL-;2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine(WX690021);2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine ISO 9001:2015 REACH;2 Ethyl 5,7 dimethyl 3H imidazo[4,5 b]pyridine,2Ethyl5,7dimethyl3Himidazo[4,5b]pyridine
- CBNumber
- CB6699657
- Molecular Formula
- C10H13N3
- Formula Weight
- 175.23
- MOL File
- 133240-06-9.mol
2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Property
- Melting point:
- 142-146 °C
- Boiling point:
- 279.7±23.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- pka
- 8.89±0.40(Predicted)
- form
- Solid
- color
- Pale Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 17645
- Product name
- 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $91
- Updated
- 2024/03/01
- Product number
- 17645
- Product name
- 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $204
- Updated
- 2024/03/01
- Product number
- 17645
- Product name
- 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
- Purity
- ≥98%
- Packaging
- 500mg
- Price
- $380
- Updated
- 2024/03/01
- Product number
- E916720
- Product name
- 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
- Packaging
- 100mg
- Price
- $195
- Updated
- 2021/12/16
- Product number
- E8605-64
- Product name
- 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
- Packaging
- 100mg
- Price
- $538
- Updated
- 2021/12/16
2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Chemical Properties,Usage,Production
Description
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is a nonpeptidic angiotensin II receptor antagonist whose imidazo[4,5-b]pyridine scaffold has been used to examine a variety of positional substitutions in the development of orally active, long duration antihypertensive agents.
Chemical Properties
Off-white powder
Uses
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is used as building block in chemical synthesis. Attributes Development Product Contact
Uses
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine (cas# 133240-06-9) is a compound useful in organic synthesis.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 5775, 1994 DOI: 10.1016/S0040-4039(00)78181-0
in vitro
in a previous study, 2-ethyl-5,7-dimethyl-3h-imidazo[4,5-b]pyridine was synthezed by reduction of 2-amino-3-nitropyridine derivatives to the corresponding diaminopyridine which was then condensed with an appropriate carboxylic acid in polyphosphoric acid. in vitro activity study showed that 2-ethyl-5,7-dimethyl-3h-imidazo[4,5-b]pyridine was a nonpeptidic angiotensin ii receptor antagonist whose imidazo[4,5-b]pyridine scaffold had been used to examine plenty of positional substitutions in the development of orally active, long duration antihypertensive agents [1].
References
[1] mantlo, n. b.,chakravarty, p.k.,ondeyka, d.l., et al. potent, orally active imadazo[4,5-b]pyridine-based angiotensin ii receptor antagonists. journal of medicinal chemistry 34(9), 2919-2922 (1991).
2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine manufacturers
- Product
- 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine 133240-06-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-31