ChemicalBook > CAS DataBase List > 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine

2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine

Product Name
2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine
CAS No.
133240-06-9
Chemical Name
2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine
Synonyms
Adenosine receptor antagonist 4;5,7-DiMethyl-2-ethyliMidazo[4,5-b]pyridine;2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-β]pyridine;2-ethyl-5,7-dimethyl-1H-imidazo[4,5-b]pyridine;2-ETHYL-5,7-DIMETHYL-3H-IMIDAZO[4,5-B]PYRIDINE;3H-Imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl-;1H-IMIDAZO[4,5-B]PYRIDINE, 2-ETHYL-5,7-DIMETHYL-;2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine(WX690021);2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine ISO 9001:2015 REACH;2 Ethyl 5,7 dimethyl 3H imidazo[4,5 b]pyridine,2Ethyl5,7dimethyl3Himidazo[4,5b]pyridine
CBNumber
CB6699657
Molecular Formula
C10H13N3
Formula Weight
175.23
MOL File
133240-06-9.mol
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2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Property

Melting point:
142-146 °C
Boiling point:
279.7±23.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
pka
8.89±0.40(Predicted)
form 
Solid
color 
Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17645
Product name
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
Purity
≥98%
Packaging
100mg
Price
$91
Updated
2024/03/01
Cayman Chemical
Product number
17645
Product name
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
Purity
≥98%
Packaging
250mg
Price
$204
Updated
2024/03/01
Cayman Chemical
Product number
17645
Product name
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
Purity
≥98%
Packaging
500mg
Price
$380
Updated
2024/03/01
TRC
Product number
E916720
Product name
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
Packaging
100mg
Price
$195
Updated
2021/12/16
Usbiological
Product number
E8605-64
Product name
2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine
Packaging
100mg
Price
$538
Updated
2021/12/16
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2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Chemical Properties,Usage,Production

Description

2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is a nonpeptidic angiotensin II receptor antagonist whose imidazo[4,5-b]pyridine scaffold has been used to examine a variety of positional substitutions in the development of orally active, long duration antihypertensive agents.

Chemical Properties

Off-white powder

Uses

2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is used as building block in chemical synthesis. Attributes Development Product Contact

Uses

2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine (cas# 133240-06-9) is a compound useful in organic synthesis.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 5775, 1994 DOI: 10.1016/S0040-4039(00)78181-0

in vitro

in a previous study, 2-ethyl-5,7-dimethyl-3h-imidazo[4,5-b]pyridine was synthezed by reduction of 2-amino-3-nitropyridine derivatives to the corresponding diaminopyridine which was then condensed with an appropriate carboxylic acid in polyphosphoric acid. in vitro activity study showed that 2-ethyl-5,7-dimethyl-3h-imidazo[4,5-b]pyridine was a nonpeptidic angiotensin ii receptor antagonist whose imidazo[4,5-b]pyridine scaffold had been used to examine plenty of positional substitutions in the development of orally active, long duration antihypertensive agents [1].

References

[1] mantlo, n. b.,chakravarty, p.k.,ondeyka, d.l., et al. potent, orally active imadazo[4,5-b]pyridine-based angiotensin ii receptor antagonists. journal of medicinal chemistry 34(9), 2919-2922 (1991).

2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine manufacturers

Dideu Industries Group Limited
Product
2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine 133240-06-9
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-31

133240-06-9, 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridineRelated Search:


  • 2-ETHYL-5,7-DIMETHYL-3H-IMIDAZO[4,5-B]PYRIDINE
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  • 3H-Imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl-
  • 2-Ethyl-5,7-diMethyl-3H-iMidazo[4,5-b]pyridine ISO 9001:2015 REACH
  • 2 Ethyl 5,7 dimethyl 3H imidazo[4,5 b]pyridine,2Ethyl5,7dimethyl3Himidazo[4,5b]pyridine
  • Adenosine receptor antagonist 4
  • 133240-06-9
  • Aromatics Compounds
  • Aromatics
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  • Heterocycles
  • Nucleotides
  • various pyridine derivatives
  • Pyridine Derivatives