Uses
ChemicalBook > CAS DataBase List > 6-BROMO-2,3-DIFLUOROBENZALDEHYDE

6-BROMO-2,3-DIFLUOROBENZALDEHYDE

Uses
Product Name
6-BROMO-2,3-DIFLUOROBENZALDEHYDE
CAS No.
360576-04-1
Chemical Name
6-BROMO-2,3-DIFLUOROBENZALDEHYDE
Synonyms
substance-name-is-not-available;2-bromo-5,6-difluorobenzaldehyde;6-BROMO-2,3-DIFLUOROBENZALDEHYDE;Benzaldehyde, 6-broMo-2,3-difluoro-;6-Bromo-2,3-difluorobenzaldehyde,98%;6-Bromo-2,3-difluorobenzaldehyde 99%;6-BROMO-2,3-DIFLUOROBENZALDEHYDE ISO 9001：2015 REACH
CBNumber
CB6713180
Molecular Formula
C7H3BrF2O
Formula Weight
221
MOL File
360576-04-1.mol
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6-BROMO-2,3-DIFLUOROBENZALDEHYDE Property

Melting point:
39-43℃
Boiling point:
225.7±35.0 °C(Predicted)
Density 
1.758±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Sensitive 
Air Sensitive
InChI
InChI=1S/C7H3BrF2O/c8-5-1-2-6(9)7(10)4(5)3-11/h1-3H
InChIKey
LAVPYRPTHABUAD-UHFFFAOYSA-N
SMILES
C(=O)C1=C(Br)C=CC(F)=C1F
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Safety

HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B678290
Product name
6-Bromo-2,3-difluorobenzaldehyde
Packaging
50mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
PC303096
Product name
6-Bromo-2,3-difluorobenzaldehyde
Purity
99%
Packaging
1g
Price
$29
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-B-09
Product name
6-Bromo-2,3-difluorobenzaldehyde?
Purity
99%
Packaging
1g
Price
$32
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB73258
Product name
6-Bromo-2,3-Difluorobenzaldehyde
Packaging
5G
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
PC303096
Product name
6-Bromo-2,3-difluorobenzaldehyde
Purity
99%
Packaging
5g
Price
$87
Updated
2021/12/16
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6-BROMO-2,3-DIFLUOROBENZALDEHYDE Chemical Properties,Usage,Production

Uses

6-BROMO-2,3-DIFLUOROBENZALDEHYDE is a useful research chemical.

Synthesis

348-61-8

68-12-2

360576-04-1

General procedure for the synthesis of 6-bromo-2,3-difluorobenzaldehyde from 3,4-difluorobromobenzene and N,N-dimethylformamide: Aryl bromide (1.0 eq.) was dissolved in anhydrous THF (0.2 M) and the reaction mixture was cooled to -78 °C under nitrogen protection. LDA (2.0 M in THF, 1.1 eq.) was added dropwise over 15 min. Stirring was continued for 20 min after addition. DMF (1.2 eq.) was then added and stirred at -78 °C for 15 min. Glacial acetic acid (4.0 eq.) was added, followed immediately by water (12 times the volume of glacial acetic acid) and the reaction mixture was slowly warmed to room temperature. The phases were separated and the aqueous phase was extracted twice with ethyl acetate. The combined organic layers were washed sequentially with dilute aqueous HCl, water and brine. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated. The resulting residue was purified by silica gel column chromatography with the eluent being a hexane solution of 0 to 5% ethyl acetate to give 6-bromo-2,3-difluorobenzaldehyde (83% yield) as a yellow oil.1H NMR (CDCl3) δ: 7.31 (t, J = 1.4 Hz, 1H), 7.45 (ddd, J = 9.0, 4.1, 1.9 Hz, 1H), 7.29 (td, J = 9.2, 8.0 Hz, 1H).

References

[1] Patent: WO2004/9578, 2004, A2. Location in patent: Page 40
[2] Patent: WO2015/67549, 2015, A1. Location in patent: Page/Page column 122
[3] Patent: US2015/126449, 2015, A1. Location in patent: Paragraph 0676 - 0678
[4] Patent: WO2009/108838, 2009, A1. Location in patent: Page/Page column 67-68

6-BROMO-2,3-DIFLUOROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-2,3-DIFLUOROBENZALDEHYDE Suppliers

China 122 India 1 United Kingdom 5 United States 12 Global 140
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 6-BROMO-2,3-DIFLUOROBENZALDEHYDE manufacturers

Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
Product
6-BROMO-2,3-DIFLUOROBENZALDEHYDE 360576-04-1
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
98%
Supply Ability
100kg
Release date
2023-03-04

360576-04-1, 6-BROMO-2,3-DIFLUOROBENZALDEHYDERelated Search:

2-Fluorobenzaldehyde 4-Fluorobenzaldehyde 3-Bromo-2,5-difluorobenzaldehyde 2-BroMo-3,6-difluorobenzaldehyde, 96% 2,3-Difluorobenzaldehyde 3-BROMO-2,6-DIFLUOROBENZALDEHYDE 4-BROMO-2,3-DIFLUOROBENZALDEHYDE 4-BROMO-2,6-DIFLUOROBENZALDEHYDE 4-BROMO-2,6-DIFLUOROBENZALDEHYDE DIMETHYL ACETAL 4-bromo-2,5-difluorobenzaldehyde 2,3-DIFLUORO-6-BROMOBENZOIC ACID 6-BROMO-2,3-DIFLUOROBENZALDEHYDE 2-BROMO-3,4,5,6-TETRAFLUOROBENZOYL CHLORIDE 2-Bromo-3,4,5,6-tetrafluorobenzoic acid 6-Bromo-2,3,4-Trifluorobenzoic Acid

  • 6-BROMO-2,3-DIFLUOROBENZALDEHYDE
  • Benzaldehyde, 6-broMo-2,3-difluoro-
  • 6-Bromo-2,3-difluorobenzaldehyde 99%
  • 6-Bromo-2,3-difluorobenzaldehyde,98%
  • 6-BROMO-2,3-DIFLUOROBENZALDEHYDE ISO 9001：2015 REACH
  • 2-bromo-5,6-difluorobenzaldehyde
  • substance-name-is-not-available
  • 360576-04-1
  • C7H3BrF2O
  • Aromatic Aldehydes & Derivatives (substituted)