4-Benzyloxy-3-methylbenzeneboronic acid

Product Name: 4-Benzyloxy-3-methylbenzeneboronic acid
CAS No.: 338454-30-1
Chemical Name: 4-Benzyloxy-3-methylbenzeneboronic acid
Synonyms: oxy-3-methyL;AKOS BRN-0646;4-BENZYLOXY-3-METHYLPHENYLBORONIC ACID;(4-BENZYLOXY-3-METHYL)BENZENEBORONIC ACID;4-Benzyloxy-3-methylbenzeneboronicacid96%;4-Benzyloxy-3-methylbenzeneboronic acid 96%;(3-methyl-4-phenylmethoxyphenyl)boronic acid;Boronic acid, B-[3-methyl-4-(phenylmethoxy)phenyl]-;4-Benzyloxy-3-methylbenzeneboronic acid(contains varying amounts of Anhydride);4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)
CBNumber: CB6723345
Molecular Formula: C14H15BO3
Formula Weight: 242.08
MOL File: 338454-30-1.mol

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4-Benzyloxy-3-methylbenzeneboronic acid Property

Melting point:: 102-106
Boiling point:: 431.6±55.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: powder to crystal
pka: 8.74±0.17(Predicted)
color: White to Almost white
CAS DataBase Reference: 338454-30-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
HazardClass: IRRITANT
HS Code: 29310095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5169
Product name: 4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 1g
Price: $65
Updated: 2025/07/31

TCI Chemical

Product number: B5169
Product name: 4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $192
Updated: 2025/07/31

TRC

Product number: B410903
Product name: 4-Benzyloxy-3-methylphenylboronicacid
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: V1882
Product name: 4-Benzyloxy-3-methylphenylboronicacid
Packaging: 1g
Price: $66
Updated: 2021/12/16

Chem-Impex

Product number: 40199
Product name: 4-Benzyloxy-3-methylphenylboronicacid,96-105%(Assaybytitration)
Purity: 96-105%(Assaybytitration)
Packaging: 1G
Price: $68.32
Updated: 2021/12/16

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4-Benzyloxy-3-methylbenzeneboronic acid Chemical Properties,Usage,Production

Uses

suzuki reaction

Synthesis

338454-32-3

338454-30-1

General procedure for the synthesis of 4-benzyloxy-3-methylbenzeneboronic acid from 2-benzyloxy-5-bromotoluene: 4-bromo-1-benzyloxy-2-methylbenzene (6.9 g, 25 mmol) was dissolved in molecularly sieve-dried tetrahydrofuran (37.5 mL) and the solution was cooled to -78 °C. A n-hexane solution of 1.6 M n-butyllithium (17 mL, 27.5 mmol) was added slowly and dropwise over a period of 30 min, keeping the reaction temperature from exceeding -70 °C. After continued stirring at this temperature for 10 min, trimethyl borate (8.3 mL, 75 mmol) was added dropwise over 25 min below -70 °C. The reaction mixture was allowed to warm slowly to room temperature and stirred overnight. The reaction mixture was then cooled to 0 °C and aqueous 1 N hydrochloric acid was added dropwise. The reaction mixture was diluted with water and ethyl acetate to separate the organic and aqueous phases, and the aqueous phase was then extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated aqueous sodium chloride solution, dried with magnesium sulfate, filtered and concentrated. 4-Benzyloxy-3-methylphenylboronic acid 3.95 g (yield 65%) was obtained as a white powder. Mass spectrum (ISN): 301.2 (M-H)-.

References

[1] Patent: US6821980, 2004, B1. Location in patent: Page column 28
[2] Chemistry - A European Journal, 2000, vol. 6, # 20, p. 3821 - 3837

4-Benzyloxy-3-methylbenzeneboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Benzyloxy-3-methylbenzeneboronic acid Suppliers

Americas 1 China 85 Europe 3 Germany 4 India 4 Japan 1 Russia 1 United Kingdom 8 United States 15 Global 122

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View Lastest Price from 4-Benzyloxy-3-methylbenzeneboronic acid manufacturers

Career Henan Chemical Co

Product: 4-Benzyloxy-3-methylbenzeneboronic acid 338454-30-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg; 5kg; 100kg
Release date: 2019-07-03

338454-30-1, 4-Benzyloxy-3-methylbenzeneboronic acidRelated Search:

2-(BENZYLOXY)-5-METHYLPHENYLBORONIC ACID 4-Benzyloxy-2-methylphenylboronic acid 4-(2'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN& 2-[4-Benzyloxy-3-(trifluoromethyl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane 4-Benzyloxy-3,5-dimethylphenylboronic acid 2-Benzyloxy-5-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile (2-(benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(pyrrolidin-1-yl)methanone 4-(3'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN& 4-BENZYLOXY-3-CHLORO-5-METHYLPHENYLBORONIC ACID 4-BENZYLOXY-3-FORMYLPHENYLBORONIC ACID 4-Benzyloxy-3-methylbenzeneboronic acid 2-(4-(Benzyloxy)-3-(trifluoromethyl)phenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane 4-(4'-CHLOROBENZYLOXY)-3,5-DIMETHYLPHEN& 2-Benzyloxy-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile 2-[4-Benzyloxy-3-(1,3-dioxan-2-yl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane 2-[4-Benzyloxy-3-(1,3-dioxan-2-yl)phenyl]-4,4,6-trimethyl-1,3,2-dioxaborinane

4-Benzyloxy-3-methylbenzeneboronic acid 96%

AKOS BRN-0646

4-Benzyloxy-3-methylbenzeneboronicacid96%

(4-BENZYLOXY-3-METHYL)BENZENEBORONIC ACID

4-BENZYLOXY-3-METHYLPHENYLBORONIC ACID

4-Benzyloxy-3-methylphenylboronic Acid (contains varying amounts of Anhydride)

(3-methyl-4-phenylmethoxyphenyl)boronic acid

oxy-3-methyL

Boronic acid, B-[3-methyl-4-(phenylmethoxy)phenyl]-

4-Benzyloxy-3-methylbenzeneboronic acid(contains varying amounts of Anhydride)

338454-30-1

blocks

BoronicAcids

Boronic acid