4-tert-Octylphenol
- Product Name
- 4-tert-Octylphenol
- CAS No.
- 140-66-9
- Chemical Name
- 4-tert-Octylphenol
- Synonyms
- Phenol, 4-(1,1,3,3-tetramethylbutyl)-;PTOP;4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOL;PARA-TERT-OCTYLPHENOL;p-octylphenol;P-T-OCTYL PHENOL;NSC 5427;NSC 7248;p-(tert-octyL;4-t-Octylphenol
- CBNumber
- CB6724049
- Molecular Formula
- C14H22O
- Formula Weight
- 206.32
- MOL File
- 140-66-9.mol
4-tert-Octylphenol Property
- Melting point:
- 79-82 °C(lit.)
- Boiling point:
- 175 °C30 mm Hg(lit.)
- Density
- 0.95 g/cm3 (20℃)
- vapor pressure
- 2Pa at 38℃
- refractive index
- 1.5003 (estimate)
- Flash point:
- 145 °C
- storage temp.
- -20°C
- solubility
- water: slightly soluble0.007g/L at 20°C
- pka
- 10.15±0.15(Predicted)
- form
- Solid
- color
- White flakes
- PH Range
- 6 at 10 g/l at 20 °C
- Water Solubility
- 7mg/L at 20℃
- BRN
- 513992
- Stability:
- Stable. Incompatible with strong oxidizing agents, strong bases.
- LogP
- 4.8 at 22℃
- CAS DataBase Reference
- 140-66-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Phenol, 4-(1,1,3,3-tetramethylbutyl)-(140-66-9)
- EPA Substance Registry System
- p-(1,1,3,3-Tetramethylbutyl)phenol (140-66-9)
Safety
- Hazard Codes
- Xn,N,Xi,F
- Risk Statements
- 21-38-41-50/53-67-66-36-11-52/53-68-62-40
- Safety Statements
- 26-36-61-60-39-16-9
- RIDADR
- 2430
- WGK Germany
- 2
- RTECS
- SM9625000
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29071300
- Hazardous Substances Data
- 140-66-9(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 442858
- Product name
- 4-tert-Octylphenol
- Purity
- analytical standard
- Packaging
- 500mg
- Price
- $52.6
- Updated
- 2024/03/01
- Product number
- 290823
- Product name
- 4-tert-Octylphenol
- Purity
- 97%
- Packaging
- 25g
- Price
- $52.8
- Updated
- 2024/03/01
- Product number
- 290823
- Product name
- 4-tert-Octylphenol
- Purity
- 97%
- Packaging
- 1kg
- Price
- $208
- Updated
- 2024/03/01
- Product number
- T0144
- Product name
- 4-(1,1,3,3-Tetramethylbutyl)phenol
- Purity
- >95.0%(GC)
- Packaging
- 25g
- Price
- $23
- Updated
- 2024/03/01
- Product number
- T0144
- Product name
- 4-(1,1,3,3-Tetramethylbutyl)phenol
- Purity
- >95.0%(GC)
- Packaging
- 500g
- Price
- $41
- Updated
- 2024/03/01
4-tert-Octylphenol Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
4-tert-Octylphenol (4t-OP) is used in manufacturing processes as an intermediate in the generation of surfactants, synthetic rubber additives, or resins. 4t-OP is also used to manufacture alkylphenol ethoxylates. It is found mainly in detergents, cleaning products, and emulsifiers and less frequently in paints, personal care products, pesticides, paper, pulp, and textiles.
Definition
ChEBI: 4-tert-Octylphenol is an alkylbenzene.
General Description
4-tert-Octylphenol is a potential environmental pollutant and it exhibits toxic and estrogenic effects on mammalian cells. It binds to estrogen receptors and exerts estrogenic actions in vitro. The transformation of the 4-tert-octylphenol upon irradiation at 253.7nm and by hydroxyl radicals generated by the photolysis (λexc = 253.7nm) of hydrogen peroxide in aqueous solution has been studied.
Health effects
4-tert-octylphenol (OP) is an endocrine-disrupting chemical that causes harmful effects to human health.a common environmental pollutant showing weak estrogenic effects. 4-tert-Octylphenol has been shown to cause harm to the male reproductive system of vertebrates.
High doses of several alkylphenols, including 4- tert-octylphenol, have altered estrogenic effects, including sex hormone levels, estrus cycles, reproductive outcomes, neonatal sexual development, as well as impaired production of steroid hormone and testicular atrophy.
Environmental Fate
Studies have shown that 4t-OP will adsorb to sediments.
Purification Methods
Crystallise the phenol from n-hexane and/or distil it in a vacuum. [Beilstein 6 III 2051, 6 IV 3484.]
Toxicity evaluation
4t-OP has been shown to be an estrogen receptor (ER) agonist. Estrogenic effects of 4t-OP have been demonstrated in human cells, with 4t-OP displacing the natural estrogen 17b estradiol from its receptor, and 4t-OP inducing cell proliferation in estrogen-dependent cell proliferation assays. In vivo confirmation of 4t-OP’s estrogenicity has been confirmed with the uterotrophic assay.
4-tert-Octylphenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-tert-Octylphenol Suppliers
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- info@trc-canada.com
- Country
- Canada
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- 6668
- Advantage
- 58
- Tel
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- Canada
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View Lastest Price from 4-tert-Octylphenol manufacturers
- Product
- 4-Tert-Octylphenol 140-66-9
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-29
- Product
- 4-tert-Octylphenol 140-66-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-19
- Product
- 4-tert-Octylphenol 140-66-9
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-23