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Methyl 2-acetylamino-3-chloropropionate

Product Name
Methyl 2-acetylamino-3-chloropropionate
CAS No.
18635-38-6
Chemical Name
Methyl 2-acetylamino-3-chloropropionate
Synonyms
Nsc146379;Ac-L-Ala(Cl)-OMe;Ac-DL-Ala(Cl)-Ome;Ac-β-chloro-Ala-OMe;Methyl 2-acetylamino;Ac-beta-chloro-Ala-OMe;2-acetylamino-3-chloropropionate;MethylN-acetyl-3-chloropropionate;Methyl2-acetylamino-3-chloropropanoate;METHYL 2-ACETYLAMINO-3-CHLOROPROPIONATE
CBNumber
CB6736495
Molecular Formula
C6H10ClNO3
Formula Weight
179.6
MOL File
18635-38-6.mol
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Methyl 2-acetylamino-3-chloropropionate Property

Melting point:
74-76°C
Boiling point:
303.6±27.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Dichloromethane, Ethyl Acetate, Methanol
pka
14.01±0.46(Predicted)
form 
Solid
color 
White
InChI
InChI=1S/C6H10ClNO3/c1-4(9)8-5(3-7)6(10)11-2/h5H,3H2,1-2H3,(H,8,9)/t5-/m0/s1
InChIKey
IGKDMFMKAAPDDN-YFKPBYRVSA-N
SMILES
C(OC)(=O)[C@H](CCl)NC(C)=O
CAS DataBase Reference
18635-38-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A172038
Product name
L-N-Acetyl-β-chloroalanineMethylEster
Packaging
50mg
Price
$155
Updated
2021/12/16
AK Scientific
Product number
R760
Product name
Methyl2-acetylamino-3-chloropropionate
Packaging
5g
Price
$198.5
Updated
2021/12/16
Activate Scientific
Product number
AS44061
Product name
N-Acetyl-3-chloro-DL-alanine methyl ester
Purity
95%
Packaging
1g
Price
$34
Updated
2021/12/16
Activate Scientific
Product number
AS44061
Product name
N-Acetyl-3-chloro-DL-alanine methyl ester
Purity
95%
Packaging
5G
Price
$90
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0036716
Product name
METHYL 2-ACETYLAMINO-3-CHLOROPROPIONATE
Purity
95.00%
Packaging
1G
Price
$619.7
Updated
2021/12/16
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Methyl 2-acetylamino-3-chloropropionate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Synthesis

32345-44-1

108-24-7

18635-38-6

30 g of (R)-methyl 2-amino-3-chloropropionate was suspended in 400 mL of diethyl ether and cooled to 0-5°C. 20 mL of ethanoic anhydride was slowly added dropwise with stirring, maintaining the reaction temperature at 0-5°C, and stirring was continued for 40 minutes after completion of the dropwise addition. Subsequently, the reaction mixture was slowly warmed to 15-25°C and stirring was continued for 1-2 hours. Upon completion of the reaction, the precipitated solid product was collected by filtration and washed with cold diethyl ether. The resulting solid was dried under vacuum to afford 33.3 g of methyl (R)-2-acetamido-3-chloropropionate in 85% yield.

References

[1] Patent: CN104710324, 2016, B. Location in patent: Paragraph 0075; 0076

Methyl 2-acetylamino-3-chloropropionate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2-acetylamino-3-chloropropionate Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from Methyl 2-acetylamino-3-chloropropionate manufacturers

Anhuyan (Hainan) Biotechnology Co., LTD
Product
Methyl 2-acetylamino-3-chloropropionate 18635-38-6
Price
US $0.00/G/KG
Min. Order
1G/KG
Purity
99%
Supply Ability
100MT
Release date
2025-04-23
Henan Aochuang Chemical Co.,Ltd.
Product
Methyl 2-acetylamino-3-chloropropionate 18635-38-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-12
Henan Fengda Chemical Co., Ltd
Product
Methyl 2-acetylamino-3-chloropropionate 18635-38-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16

18635-38-6, Methyl 2-acetylamino-3-chloropropionateRelated Search:


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  • 18635-38-6
  • C6H10ClNO3
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  • Chiral Reagents