5-FLUORO-2-METHYLBENZOXAZOLE

Product Name: 5-FLUORO-2-METHYLBENZOXAZOLE
CAS No.: 701-16-6
Chemical Name: 5-FLUORO-2-METHYLBENZOXAZOLE
Synonyms: fluoromethylbenzoxazole;5-FLUORO-2-METHYLBENZOXAZOLE;Benzoxazole, 5-fluoro-2-methyl-;5-Fluoro-2-methylbenzoxazole>5-Fluoro-2-methylbenzo[d]oxazole;5-Fluoro-2-methyl-1,3-benzoxazole;5-FLUORO-2-METHYLBENZOXAZOLE 97+%
CBNumber: CB6748179
Molecular Formula: C8H6FNO
Formula Weight: 151.14
MOL File: 701-16-6.mol

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5-FLUORO-2-METHYLBENZOXAZOLE Property

Boiling point:: 90°C 10mm
Density: 1.23
refractive index: 1.5210 to 1.5240
storage temp.: Sealed in dry,Room Temperature
pka: 1.05±0.10(Predicted)
Specific Gravity: 1.23
Appearance: Yellow to orange Liquid

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: F0420
Product name: 5-Fluoro-2-methylbenzoxazole
Purity: >97.0%(GC)
Packaging: 1g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: F0420
Product name: 5-Fluoro-2-methylbenzoxazole
Purity: >97.0%(GC)
Packaging: 5g
Price: $131
Updated: 2025/07/31

TRC

Product number: F401718
Product name: 5-Fluoro-2-Methylbenzoxazole
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC906427
Product name: 5-Fluoro-2-methylbenzoxazole
Purity: 97%
Packaging: 1g
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: 6772AL
Product name: 5-Fluoro-2-methylbenzoxazole
Packaging: 5g
Price: $244
Updated: 2021/12/16

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5-FLUORO-2-METHYLBENZOXAZOLE Chemical Properties,Usage,Production

Uses

5-Fluoro-2-Methylbenzoxazole is used as a reactant in the preparation of benzothiadiazine compounds as CD73 inhibitors.

Synthesis

399-97-3

78-39-7

701-16-6

Procedure for the synthesis of 5-fluoro-2-methylbenzoxazole: 2-amino-4-fluorophenol (1.01 g, 7.95 mmol, 1.0 eq.), triethyl orthoacetate (1.60 mL, 8.7 mmol, 1.1 eq.), and bismuth(III) trifluoromethanesulfonate (50 mg) were mixed and stirred for 30 min at room temperature. Upon completion of the reaction, the reaction mixture was diluted with dichloromethane and purified by rapid chromatography on silica gel (eluent: dichloromethane) to afford 5-fluoro-2-methylbenzoxazole as a clear liquid in a yield of 1.045 g (87% yield). The liquid could be converted to a crystalline solid at lower than 5 °C. Mass spectrum (MALDI-TOF): MH+ = 152. UV/Vis spectrum (methanol): maximum absorption wavelength λmax = 282, 276, 230 nm. 1H NMR (400 MHz, CDCl3): δ 2.60 (s, 3H), 7.02 (1H, td), 7.33 (1H, dd), 7.39 (1H, dd).

References

[1] Patent: WO2008/40994, 2008, A2. Location in patent: Page/Page column 25
[2] Patent: WO2017/98421, 2017, A1. Location in patent: Page/Page column 223

5-FLUORO-2-METHYLBENZOXAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUORO-2-METHYLBENZOXAZOLE Suppliers

Americas 1 China 56 Europe 1 Germany 3 India 3 Japan 2 United Kingdom 3 United States 5 Global 74

J & K SCIENTIFIC LTD.

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View Lastest Price from 5-FLUORO-2-METHYLBENZOXAZOLE manufacturers

Honest Joy Holdings Limited

Product: 5-Fluoro-2-methylbenzoxazole 701-16-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.4%
Supply Ability: 100 tons
Release date: 2022-01-14

Career Henan Chemical Co

Product: 5-FLUORO-2-METHYLBENZOXAZOLE 701-16-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-23

701-16-6, 5-FLUORO-2-METHYLBENZOXAZOLERelated Search:

2-Methylbenzoxazole DL-ISOSERINE 6-FLUORO-2-METHYLBENZOXAZOLE 97,6-FLUORO-2-METHYLBENZOXAZOLE 97% DL-Isoserine 6-FLUORO-2-METHYLBENZOXAZOLE 5-Fluorobenzoxazole 5-FLUORO-1,3-BENZOXAZOLE-2-CARBOXYLIC ACID 5-FLUOROBENZO[D]OXAZOLE-2-CARBALDEHYDE 5-FLUORO-2-METHYLBENZOXAZOLE

fluoromethylbenzoxazole

5-FLUORO-2-METHYLBENZOXAZOLE

5-FLUORO-2-METHYLBENZOXAZOLE 97+%

5-Fluoro-2-methylbenzo[d]oxazole

5-Fluoro-2-methyl-1,3-benzoxazole

5-Fluoro-2-methylbenzoxazole&gt

Benzoxazole, 5-fluoro-2-methyl-

701-16-6