ChemicalBook > CAS DataBase List > 3-Chloropropylamine hydrochloride

3-Chloropropylamine hydrochloride

Product Name
3-Chloropropylamine hydrochloride
CAS No.
6276-54-6
Chemical Name
3-Chloropropylamine hydrochloride
Synonyms
3-CHLOROPROPYLAMINE HCL;1-Amino-3-chloroprop;Roxatidine Impurity 44;3-Chlotoptopulamine HCl;3-Mefenorexhydrochloride;3-Chloropropan-1-amine HCL;Roxatidine Impurity 12 HCl;3-Chloro-1-propanamine HCl;1-Amino-3-chloropropane hcl;ChloropropylaMinehydrochloride
CBNumber
CB6753920
Molecular Formula
C3H9Cl2N
Formula Weight
130.02
MOL File
6276-54-6.mol
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3-Chloropropylamine hydrochloride Property

Melting point:
145-150 °C(lit.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder or Chunks
color 
Off-white to yellow-beige
BRN 
3667451
InChI
InChI=1S/C3H8ClN.ClH/c4-2-1-3-5;/h1-3,5H2;1H
InChIKey
IHPRVZKJZGXTBQ-UHFFFAOYSA-N
SMILES
C(CCl)CN.Cl
CAS DataBase Reference
6276-54-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37-36-37/39
WGK Germany 
3
HS Code 
29211980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
142549
Product name
3-Chloropropylamine hydrochloride
Purity
98%
Packaging
50g
Price
$64.5
Updated
2025/07/31
Sigma-Aldrich
Product number
142549
Product name
3-Chloropropylamine hydrochloride
Purity
98%
Packaging
250g
Price
$148.2
Updated
2025/07/31
TCI Chemical
Product number
C1062
Product name
3-Chloropropylamine Hydrochloride
Purity
>97.0%(T)
Packaging
25g
Price
$23
Updated
2025/07/31
TCI Chemical
Product number
C1062
Product name
3-Chloropropylamine Hydrochloride
Purity
>97.0%(T)
Packaging
100g
Price
$61
Updated
2025/07/31
TRC
Product number
C350935
Product name
3-Chloropropylamine hydrochloride
Packaging
1g
Price
$55
Updated
2021/12/16
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3-Chloropropylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

off-white to yellow-beige crystalline

Uses

3-Chloropropylamine hydrochloride was used in chemical treatment of carbon-enriched fly ash concentrates. It was used in the synthesis of linear, star and comb-like polyacrylamides by atomic transfer radical polymerization. It was used in the synthesis of halogen-functionalized aliphatic polyketones (macroinitiators).

Synthesis

156-87-6

6276-54-6

General procedure for the synthesis of 3-chloropropylamine hydrochloride from 3-amino-1-propanol: An anhydrous chloroform (30 mL) solution of thionyl chloride (8.68 g, 1.32 mmol) was slowly added dropwise to 3-amino-1-propanol (4.49 g, 59.19 mmol) at 0-10°C. The reaction mixture was heated to room temperature and refluxed for 3 hours. The reaction mixture was gradually warmed to room temperature and then heated to reflux for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and the precipitate was collected by filtration to afford the target product 3-chloropropylamine hydrochloride (7.07 g, 55.15 mmol, 93% yield) as a green solid. Electrospray mass spectrometry (ESMS) showed m/z 94 ([M+H]+).

References

[1] Patent: WO2014/18571, 2014, A2. Location in patent: Paragraph 00463
[2] Patent: WO2014/18570, 2014, A1. Location in patent: Paragraph 00261
[3] Angewandte Chemie - International Edition, 2018, vol. 57, # 19, p. 5413 - 5417
[4] Angew. Chem., 2018, vol. 130, p. 5511 - 5515,5

3-Chloropropylamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Chloropropylamine hydrochloride Suppliers

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View Lastest Price from 3-Chloropropylamine hydrochloride manufacturers

Hangzhou Verychem Science And Technology Co.Ltd
Product
3-Chloropropylamine hydrochloride 6276-54-6
Price
US $0.00-0.00/kg
Min. Order
25kg
Purity
0.99
Supply Ability
10 tons
Release date
2025-07-28
Hebei Chuanghai Biotechnology Co., Ltd
Product
3-Chloropropylamine hydrochloride 6276-54-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31
Henan Aochuang Chemical Co.,Ltd.
Product
3-Chloropropylamine hydrochloride 6276-54-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-16

6276-54-6, 3-Chloropropylamine hydrochlorideRelated Search:

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  • 3-Chlotoptopulamine HCl
  • 3-Chloropropan-1-amine HCL
  • Roxatidine Impurity 12(Hydrochloride)
  • 1-Amino-3-chloropropane hcl
  • 3-chloro-1-Propanamine hydrochloride
  • Roxatidine Impurity 12 HCl
  • Roxatidine Impurity 44
  • Roxatidine Impurity(Hydrochloride)
  • 3-Chloro-1-propanamine HCl
  • 6276-54-6
  • 228-474-6
  • C3H8ClNHCl
  • ClCH2CH2CH2NH2HCl
  • C3H8ClNClH
  • C3H9Cl2N
  • C3H8ClNHClC3H9Cl2N
  • C3H8ClNxHCl
  • ClCH23NH2HCl
  • 蠅-Haloalkylamines
  • 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides
  • Organic Building Blocks
  • Nitrogen Compounds
  • AMINE
  • Building Blocks
  • Amine Salts
  • omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
  • omega-Haloalkylamines
  • bc0001