3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE
- Product Name
- 3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE
- CAS No.
- 5407-04-5
- Chemical Name
- 3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE
- Synonyms
- DMPC;3-Dimethylaminopropylchloride hydrochloride;2-DIMETHYLAMINO ISOPROPYL CHLORIDE HCL;3-CHLORO-N,N-DIMETHYLPROPAN-1-AMINE HYDROCHLORIDE;3-Dimethylaminopropylmagnesium chloride;3-Chloro-N,N-dimethylpropylamine hydrochloride;B-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE;1-(DIMETHYLAMINO)-2-CHLOROPROPANE HYDROCHLORIDE;2-DMPC;oride hydrochL
- CBNumber
- CB9173493
- Molecular Formula
- C5H13Cl2N
- Formula Weight
- 158.07
- MOL File
- 5407-04-5.mol
3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Property
- Melting point:
- 187-190 °C(lit.)
- Boiling point:
- 50 °C(Press: 40 Torr)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- 2000g/l
- form
- Solid
- color
- White to Off-White
- PH
- 5-6 (500g/l, H2O, 20℃)
- Water Solubility
- soluble
- Sensitive
- Hygroscopic
- BRN
- 3670046
- InChI
- InChI=1S/C5H12ClN.ClH/c1-7(2)5-3-4-6;/h3-5H2,1-2H3;1H
- InChIKey
- LJQNMDZRCXJETK-UHFFFAOYSA-N
- SMILES
- C(CCCl)N(C)C.Cl
- CAS DataBase Reference
- 5407-04-5(CAS DataBase Reference)
- EPA Substance Registry System
- 3-Chloro-N,N-dimethyl-1-propanamine hydrochloride (5407-04-5)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-52/53
- Safety Statements
- 26-61-37/39-36
- WGK Germany
- 3
- RTECS
- TY1225000
- F
- 3
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29211990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D145203
- Product name
- 3-Dimethylamino-1-propyl chloride hydrochloride
- Purity
- 96%
- Packaging
- 100g
- Price
- $54.6
- Updated
- 2025/07/31
- Product number
- D0663
- Product name
- 3-(Dimethylamino)propyl Chloride Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $19
- Updated
- 2025/07/31
- Product number
- D0663
- Product name
- 3-(Dimethylamino)propyl Chloride Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 250g
- Price
- $79
- Updated
- 2025/07/31
- Product number
- D461800
- Product name
- 3-(Dimethylamino)propyl Chloride Hydrochloride
- Packaging
- 2.5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- FD22348
- Product name
- 3-Dimethylaminopropyl chloride hydrochloride
- Packaging
- 1kg
- Price
- $150
- Updated
- 2021/12/16
3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White to yellowish crystalline powder
Uses
Dimethylaminopropyl chloride, hydrochloride is used mainly as a pharmaceutical intermediate for the synthesis of many types of drugs, as an agricultural chemical intermediate, as a photographic chemical intermediate, and as a biochemical reagent for enzyme and other studies. The compound shows mutagenic activity.
Uses
3-(Dimethylamino)propyl chloride hydrochloride (DMPC) is used as intermediate for the syntheses of pharmaceuticals (e.g. amitriptyline, bencyclane, benzydamine, cyclobenzaprine and imipramine). Product Data Sheet
Synthesis
3179-63-3
5407-04-5
Dithionyl chloride (21 g, 1.2 eq.) was added slowly and dropwise to a stirred solution of 3-dimethylamino-1-propanol (15 g, 1.0 eq.) dissolved in 150 mL of chloroform at 0 °C. Subsequently, the reaction mixture was heated to reflux and maintained for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to obtain the crude product. The crude product was washed with a mixture of dichloromethane and petroleum ether (1:10, 50 mL, v/v) to give N,N-dimethylaminopropyl chloride hydrochloride (22 g, 98% yield).
References
[1] Patent: WO2013/97773, 2013, A1. Location in patent: Paragraph 0248
[2] Journal of Polymer Science, Part A: Polymer Chemistry, 2014, vol. 52, # 5, p. 671 - 679
3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE manufacturers
- Product
- 3-Dimethylaminopropylchloride hydrochloride 5407-04-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 1 tons
- Release date
- 2025-11-24
- Product
- 2-DMPC 5407-04-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kgs
- Release date
- 2025-09-24
- Product
- 4-Chlorosalicylic acid 5407-04-5
- Price
- US $49.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2025-08-26