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3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE

Product Name
3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE
CAS No.
5407-04-5
Chemical Name
3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE
Synonyms
DMPC;3-Dimethylaminopropylchloride hydrochloride;2-DIMETHYLAMINO ISOPROPYL CHLORIDE HCL;3-CHLORO-N,N-DIMETHYLPROPAN-1-AMINE HYDROCHLORIDE;3-Dimethylaminopropylmagnesium chloride;3-Chloro-N,N-dimethylpropylamine hydrochloride;B-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE;1-(DIMETHYLAMINO)-2-CHLOROPROPANE HYDROCHLORIDE;2-DMPC;oride hydrochL
CBNumber
CB9173493
Molecular Formula
C5H13Cl2N
Formula Weight
158.07
MOL File
5407-04-5.mol
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3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Property

Melting point:
187-190 °C(lit.)
Boiling point:
50 °C(Press: 40 Torr)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
2000g/l
form 
Solid
color 
White to Off-White
PH
5-6 (500g/l, H2O, 20℃)
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
3670046
InChI
InChI=1S/C5H12ClN.ClH/c1-7(2)5-3-4-6;/h3-5H2,1-2H3;1H
InChIKey
LJQNMDZRCXJETK-UHFFFAOYSA-N
SMILES
C(CCCl)N(C)C.Cl
CAS DataBase Reference
5407-04-5(CAS DataBase Reference)
EPA Substance Registry System
3-Chloro-N,N-dimethyl-1-propanamine hydrochloride (5407-04-5)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-52/53
Safety Statements 
26-61-37/39-36
WGK Germany 
3
RTECS 
TY1225000
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29211990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D145203
Product name
3-Dimethylamino-1-propyl chloride hydrochloride
Purity
96%
Packaging
100g
Price
$54.6
Updated
2025/07/31
TCI Chemical
Product number
D0663
Product name
3-(Dimethylamino)propyl Chloride Hydrochloride
Purity
>98.0%(T)
Packaging
25g
Price
$19
Updated
2025/07/31
TCI Chemical
Product number
D0663
Product name
3-(Dimethylamino)propyl Chloride Hydrochloride
Purity
>98.0%(T)
Packaging
250g
Price
$79
Updated
2025/07/31
TRC
Product number
D461800
Product name
3-(Dimethylamino)propyl Chloride Hydrochloride
Packaging
2.5g
Price
$145
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22348
Product name
3-Dimethylaminopropyl chloride hydrochloride
Packaging
1kg
Price
$150
Updated
2021/12/16
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3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White to yellowish crystalline powder

Uses

Dimethylaminopropyl chloride, hydrochloride is used mainly as a pharmaceutical intermediate for the synthesis of many types of drugs, as an agricultural chemical intermediate, as a photographic chemical intermediate, and as a biochemical reagent for enzyme and other studies. The compound shows mutagenic activity.

Uses

3-(Dimethylamino)propyl chloride hydrochloride (DMPC) is used as intermediate for the syntheses of pharmaceuticals (e.g. amitriptyline, bencyclane, benzydamine, cyclobenzaprine and imipramine). Product Data Sheet

Synthesis

3179-63-3

5407-04-5

Dithionyl chloride (21 g, 1.2 eq.) was added slowly and dropwise to a stirred solution of 3-dimethylamino-1-propanol (15 g, 1.0 eq.) dissolved in 150 mL of chloroform at 0 °C. Subsequently, the reaction mixture was heated to reflux and maintained for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to obtain the crude product. The crude product was washed with a mixture of dichloromethane and petroleum ether (1:10, 50 mL, v/v) to give N,N-dimethylaminopropyl chloride hydrochloride (22 g, 98% yield).

References

[1] Patent: WO2013/97773, 2013, A1. Location in patent: Paragraph 0248
[2] Journal of Polymer Science, Part A: Polymer Chemistry, 2014, vol. 52, # 5, p. 671 - 679

3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE Suppliers

Shijiazhuang Ruitian Biochemical Co. Ltd
Tel
15831127780
Email
52714113@qq.com
Country
China
ProdList
258
Advantage
58
Henan yu Chen pharmaceutical co., LTD
Tel
0374-5699939 18864655557
Fax
+86-374-5699958
Email
yuchenchem@126.com
Country
China
ProdList
30
Advantage
58
Inner Mongolia Ruifeng Pharmaceutical Co., Ltd
Tel
13912228943
Email
119155679@qq.com
Country
China
ProdList
7
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58
Zhemical Co., Ltd.
Tel
760-89935616
Fax
0760-86925770
Email
zc@zhemical.com
Country
China
ProdList
75
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57
Wuhan yuqing jiaheng pharmaceutical co. LTD
Tel
027-83855389 13545340383
Fax
027-83855389
Email
2586905842@qq.com
Country
China
ProdList
999
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58
Shanghai Peiling Biological Technology Co., Ltd
Tel
13127581762
Email
peilingchem@sina.com
Country
China
ProdList
480
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDE manufacturers

Hangzhou Verychem Science And Technology Co.Ltd
Product
3-Dimethylaminopropylchloride hydrochloride 5407-04-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
1 tons
Release date
2025-11-24
Shaanxi Dideu New Materials Co. Ltd
Product
2-DMPC 5407-04-5
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kgs
Release date
2025-09-24
Shaanxi Dideu Medichem Co. Ltd
Product
4-Chlorosalicylic acid 5407-04-5
Price
US $49.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2025-08-26

5407-04-5, 3-(DIMETHYLAMINO)PROPYL CHLORIDE HYDROCHLORIDERelated Search:


  • N-(2-CHLORO-PROPYL)DIMETHYLAMINE
  • N-(2-CHLOROPROPYL)-N,N-DIMETHYLAMMONIUM CHLORIDE
  • 1-Chloro-3-(N,N-dimethyl)aminopropanehydrochloride
  • 1-Chloro-3-dimethylaminopropane,hydrochloride
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  • 1-Dimethylamino-3-propylchloridehydrochloride
  • 1-Propanamine,3-chloro-N,N-dimethyl-,hydrochloride
  • 2-DMPC
  • 2-DIMETHYLAMINO ISOPROPYL CHLORIDE HCL
  • 2 CHLORO-N,N-DIMETHYLPROPANAMINE HYDROCHLORIDE
  • 2-CHLOROPROPYLDIMETHYLAMMONIUM CHLORIDE
  • 2-CHLORO-1-DIMETHYLAMINOPROPANE HYDROCHLORIDE
  • B-DIMETHYLAMINOISOPROPYL CHLORIDE HYDROCHLORIDE
  • BETA-DIMETHYLAMINOISOPROPYL CHLORIDE HCL
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  • 1-DIMETHYL AMINOISOPROPYL CHLORIDE HYDROCHLORIDE
  • 1-DIMETHYLAMINO-2-PROPYL CHLORIDE HYDROCHLORIDE
  • 1-(DIMETHYLAMINO)-2-CHLOROPROPANE HYDROCHLORIDE
  • 3-Dimethylamino-1-chloropropane hydrochloride
  • N-(3-Chloropropyl)dimethylamine hydrochloride
  • B-DIMETHYLAMINOPROPYL CHLORIDE*HYDROCHLO RIDE
  • DiMethylAminoPropylChloride.Hcl(Liquid)
  • (3-Chloropropyl)-DimethylamineHydrochloride
  • N-(3-Chloropropyl)dimethylamine HCl
  • N, N- two dimethylamino propyl chloride hydrochloride
  • 3-(N,N-DIMETHYLAMINO)-1-PROPYLCHLORIDEHYDROCHLORIDE
  • N,N-Dimethylamino-2-chloropropane hydrochloride
  • 3-CHLORO-N,N-DIMETHYLPROPAN-1-AMINE HYDROCHLORIDE
  • 3-DIMETHYLAMINOPROPYLCHLORIDE HYDROCHLORIDE 99%
  • 3-Chloro-N,N-dimethylpropylamine hydrochloride
  • 3-Chloropropyldimethylammonium chloride
  • 3-Dimethylaminopropylchloride hydrochloride
  • DMPC
  • 3-(N,N-DIMETHYLAMINO)CHLOROPROPANE,HCL
  • 3-Dimethylaminorpopyl chloride hydrochloride
  • 3-Dimethylaminopropylmagnesium chloride
  • 3-dimethylaminoaminopropane hydrochloride
  • oride hydrochL
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  • 3-chloro-n,n-dimethyl-1-propylaminhydrochloride
  • 3-Chloro-N,N-dimethylpropylamine hydrochloride, N,N-Dimethyl(3-chloropropyl)amine hydrochloride
  • 3-Chloro-N,N-dimethylpropylamine
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  • 3-(Dimethylamino)propyl chloride hydrochloride, 1-Chloro-3-(dimethylamino)propane hydrochloride
  • 1-PropanaMine, 3-chloro-N,N-diMethyl-, hydrochloride (1:1)
  • 3-DiMethylaMino-1-propyl chloride hydrochloride 96%
  • N, N- diMethylaMino-chloropropane hydrochloride 3-chloro -N, N- diMethyl-propylaMine hydrochloride N, N- diMethylaMino-3-chloropropane hydrochloride
  • N-(3-CHLOROPROPYL)-N,N-DIMETHYLAMMONIUM
  • dMpc(5407-04-5)
  • 3-DIMETHYAMINOPROPYLCHLORIDE HYDROCHLORIDE - SOLUTION IN WATER
  • N,N-dimethyl-3-chloropropyl aminehydrochloride 5407-4-5
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  • N,N-Dimethyl-3-chloropropylamine Hy
  • 3-(Dimethylamino)propyl Chloride Hydrochloride &gt
  • 3-Dimethylaminopropyl chloride hydrochloride, 99%, for synthesis