1-N-Boc-Aminocyclopentanecarboxylic acid
- Product Name
- 1-N-Boc-Aminocyclopentanecarboxylic acid
- CAS No.
- 35264-09-6
- Chemical Name
- 1-N-Boc-Aminocyclopentanecarboxylic acid
- Synonyms
- BOC-CLE-OH;Boc-AC5C-OH;Boc-Cyclolencine;BOC-CYCLOLEUCINE;BOC-NH(1)CPNE-OH;1-(Boc-amino)cycL;N-BOC-CYCLOLEUCINE;N-ALPHA-T-BUTOXYCARBONYL-CYCLOLEUCINE;Boc-1-aminocyclopentane-1-carboxy acid;BOC-1-AMINOCYCLOPENTANECARBOXYLIC ACID
- CBNumber
- CB6768054
- Molecular Formula
- C11H19NO4
- Formula Weight
- 229.27
- MOL File
- 35264-09-6.mol
1-N-Boc-Aminocyclopentanecarboxylic acid Property
- Melting point:
- 130-135 °C
- Boiling point:
- 376.6±21.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- pka
- 4.14±0.20(Predicted)
- form
- Crystalline Powder
- color
- White to off-white
- Water Solubility
- Soluble in hot water
- BRN
- 2734412
- CAS DataBase Reference
- 35264-09-6(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B3831
- Product name
- 1-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $47
- Updated
- 2023/06/20
- Product number
- B3831
- Product name
- 1-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $123
- Updated
- 2025/07/31
- Product number
- B646248
- Product name
- Boc-Cycloleucine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B646248
- Product name
- Boc-Cycloleucine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 236122
- Product name
- Boc-cycloleucine
- Packaging
- 1g
- Price
- $179
- Updated
- 2021/12/16
1-N-Boc-Aminocyclopentanecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder
Uses
Boc-Cycloleucine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
24424-99-5
52-52-8
35264-09-6
Cycloleucine (1.0 g, 7.74 mmol), triethylamine (Et3N, 5.4 mL, 38.7 mmol), 1 M aqueous NaOH (7.74 mL, 7.74 mmol) and acetonitrile (CH3CN, 10 mL) were added to a 250 mL round-bottom flask. The resulting clarified solution was cooled to 0 °C, followed by the slow addition of di-tert-butyl dicarbonate ((Boc)2O). The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 h. A white precipitate was generated during the reaction. After completion of the reaction, the mixture was concentrated and the residue was dissolved in a solvent mixture of ethyl acetate (EtOAc) and water (1:1, 100 mL). The organic phase was separated and the aqueous phase was acidified with 10% HCl and then extracted three times with EtOAc. All organic phases were combined, washed with water and saturated saline in turn, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to give 1-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid as a white solid (1.29 g, 73% yield).
References
[1] Chemistry - A European Journal, 2011, vol. 17, # 19, p. 5256 - 5260
[2] Tetrahedron Letters, 1996, vol. 37, # 20, p. 3441 - 3444
[3] Organic Process Research and Development, 1998, vol. 2, # 4, p. 238 - 244
[4] Patent: WO2004/22534, 2004, A1. Location in patent: Page 39
[5] Patent: WO2017/21922, 2017, A1. Location in patent: Page/Page column 29
1-N-Boc-Aminocyclopentanecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1-N-Boc-Aminocyclopentanecarboxylic acid Suppliers
- Tel
- --
- Fax
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- ruf.szilvi@infarmatik.hu
- Country
- Hungary
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View Lastest Price from 1-N-Boc-Aminocyclopentanecarboxylic acid manufacturers
- Product
- Boc-Cyclolencine 35264-09-6
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 100KG
- Release date
- 2025-08-20
- Product
- 1-N-Boc-Aminocyclopentanecarboxylic acid 35264-09-6
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-10