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ALLOXAN MONOHYDRATE

Product Name
ALLOXAN MONOHYDRATE
CAS No.
2244-11-3
Chemical Name
ALLOXAN MONOHYDRATE
Synonyms
Alloxan99%;MESOXALYLUREA;Alloxan, 98.5%;5,6-DIOXYURACIL;Urea monohydrate;ALLOXANE DIHYDRATE;ALLOXAN MONOHYDRATE;Alloxan Momohydrate;ALLOXAN ( HYDRATE) GR;LABOTEST-BB LT00138148
CBNumber
CB6771957
Molecular Formula
C4H4N2O5
Formula Weight
160.09
MOL File
2244-11-3.mol
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ALLOXAN MONOHYDRATE Property

Melting point:
255 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
H2O: may be hazy yellow
form 
Crystalline Powder
color 
Off-white to beige-yellow
Water Solubility 
Soluble in water, ethanol, acetone, glacial acetic acid and methanol. Slightly soluble in chloroform, petroleum ether, toluene, ethyl acetate and acetic anhydride. Insoluble in ether.
Sensitive 
Air Sensitive
Merck 
14,282
BRN 
5309394
CAS DataBase Reference
2244-11-3(CAS DataBase Reference)
EPA Substance Registry System
2,4,5,6(1H,3H)-Pyrimidinetetrone, monohydrate (2244-11-3)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
36-26-36/37
WGK Germany 
3
RTECS 
UW0492000
TSCA 
Yes
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A7413
Product name
Alloxan monohydrate
Purity
98%
Packaging
10g
Price
$51
Updated
2024/03/01
Sigma-Aldrich
Product number
A7413
Product name
Alloxan monohydrate
Purity
98%
Packaging
25g
Price
$79.4
Updated
2024/03/01
TCI Chemical
Product number
A0216
Product name
Alloxan Monohydrate
Packaging
5G
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
A0216
Product name
Alloxan Monohydrate
Purity
>98.0%(T)
Packaging
25g
Price
$109
Updated
2024/03/01
Alfa Aesar
Product number
A15324
Product name
Alloxan monohydrate, 98%
Packaging
25g
Price
$54.9
Updated
2023/06/20
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ALLOXAN MONOHYDRATE Chemical Properties,Usage,Production

Chemical Properties

Off-white to beige-yellowish crystalline powder

Uses

specific cytotoxin (beta pacreatic cell)

Uses

Cytotoxic compound that causes oxidative base damage to nuclear DNAAlloxan monohydrate is used as a precursor to prepare purple dye murexide. It is also used in research models to induce diabetes and destroy beta cells. Further, it is a strong oxidizing agent and it forms a hemiacetal with its reduced reaction product dialuric acid.

Uses

A cytotoxic compound, Alloxan Monohydrate causes oxidative base damage to nuclear DNA.

Safety Profile

Poison by intravenous route. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Recrystallisation from H2O gave the tetrahydrate in large prisms or rhombs. On heating at 100o, or on exposure to air, this is converted to the monohydrate. Dissolve it in its own weight of boiling H2O and cool it for several days below 0o; the tetrahydrate crystallises from solution much more slowly when free from HNO3. It is less soluble in bicarbonate solutions than in H2O. Drying the solid over H2SO4 yields the monohydrate. The anhydrous crystals can be obtained by recrystallisation from dry Me2CO or AcOH followed by washing with dry Et2O, or by sublimation in a vacuum. On heating it turns pink at 230o and decomposes at ca 256o. It is acidic to litmus. [Hartman & Sheppard Org Synth Coll Vol III 37 1955.] It forms a compound with urea which crystallises from H2O in yellow needles that become red at 170o and decompose at 185-186o. [Beilstein 24 H 500, 24 I 428, 24 II 301, 24 III/IV 2137.]

ALLOXAN MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ALLOXAN MONOHYDRATE Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from ALLOXAN MONOHYDRATE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Alloxan Monohydrate 2244-11-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-06
Career Henan Chemical Co
Product
ALLOXAN MONOHYDRATE 2244-11-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98-99.9%
Supply Ability
100kg
Release date
2020-02-03
Career Henan Chemical Co
Product
ALLOXAN MONOHYDRATE 2244-13-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kg
Release date
2019-08-30

2244-11-3, ALLOXAN MONOHYDRATERelated Search:


  • 2,4,5,6(1H,3H)-Pyrimidinetetrone, 2,4,5,6-Tetraoxypyrimidine, 5,6-Dioxyuracil
  • 2,4,5,6-tetraoxohexahydropyrimidinehydrate
  • mesoxalylcarbamidemonohydrate
  • LABOTEST-BB LT00138148
  • MESOXALYLUREA
  • MESOXALYLUREA, MONOHYDRATE
  • 5,6-DIOXYURACIL
  • 5,6-DIOXYURACIL MONOHYDRATE
  • ALLOXANE DIHYDRATE
  • ALLOXAN MONOHYDRATE
  • 2,4,5,6-TETRAOXYPYRIMIDINE
  • 2,4,5,6-TETRAOXYPYRIMIDINE MONOHYDRATE
  • 2,4,5,6(1H,3H)-PYRIMIDINETETRONE MONOHYDRATE
  • Alloxan99%
  • ALLOXAN ( HYDRATE) GR
  • Pyrimidine-2,4,5,6(1H,3H)-tetrone hydrate
  • 2,4,5,6(1h,3h)-pyrimidinetetronehydrate
  • Alloxan monohydrate,98%
  • Alloxan Momohydrate
  • Alloxan Monohydrate, 98% 25GR
  • PyriMidine-2,4,5,6(1H,3H)-tetraone hydrate
  • 1,3-Diazinane-2,4,5,6-tetrone hydrate
  • Alloxan monohydrate ,99%
  • 2,4,5,6(1H,3H)-PyriMidinetetrone,hydrate (1:1)
  • Alloxan monohydrate≥ 98% (Assay)
  • 2,4,5,6(1H,3H)-Pyrimidinetetrone monohydrate 2,4,5,6(1H,3H)-Pyrimidinetetrone monohydrate
  • Urea monohydrate
  • Alloxan Monohydrate&gt
  • ALLOXAN MONOHYDRATE USP/EP/BP
  • Alloxan, 98.5%
  • N-[(E)-3-methylbutylideneamino]-2,4-dinitroaniline
  • Alloxan Monohydrate extrapure, 98%
  • Alloxan Monohydrate, ≥ 98.0%
  • Alloxan Monohydrate 98% Extra Pure
  • 2244-11-3
  • 2244-13-3
  • 2244-11-03
  • 125-95-2
  • CONHCONHCOCOH2
  • C4H2N2O4xH2O
  • C4H2N2O4H2O
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines
  • buildingblock
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Active Pharmaceutical Ingredients