Domagrozumab
- Product Name
- Domagrozumab
- CAS No.
- 1629605-31-7
- Chemical Name
- Domagrozumab
- Synonyms
- Domagrozumab;Domagrozumab (anti-GDF8);Research Grade Domagrozumab;Research Grade Domagrozumab(DHA30603)
- CBNumber
- CB68080985
- Formula Weight
- 0
- MOL File
- Mol file
Domagrozumab Property
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- HY-P99857
- Product name
- Domagrozumab
- Purity
- 96.34%
- Packaging
- 1mg
- Price
- $380
- Updated
- 2026/05/26
- Product number
- HY-P99857
- Product name
- Domagrozumab
- Purity
- 96.34%
- Packaging
- 5mg
- Price
- $1140
- Updated
- 2026/05/26
- Product number
- HY-P99857
- Product name
- Domagrozumab
- Purity
- 96.34%
- Packaging
- 10mg
- Price
- $1805
- Updated
- 2026/05/26
- Product number
- A979
- Product name
- Domagrozumab Biosimilar（Anti-GDF8 / Myostatin Reference Antibody）
- Purity
- >98%
- Packaging
- 1mg
- Price
- $450
- Updated
- 2026/05/24
- Product number
- A979
- Product name
- Domagrozumab Biosimilar（Anti-GDF8 / Myostatin Reference Antibody）
- Purity
- >98%
- Packaging
- 5mg
- Price
- $750
- Updated
- 2026/05/24
Domagrozumab Chemical Properties,Usage,Production
Uses
Domagrozumab is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD)[1].
in vivo
Domagrozumab (PF-06252616; 10 and 30 mg/kg; i.v.) increases myostatin levels in a dose-dependent manner and induces skeletal muscle hypertrophy in cynomolgus monkeys[1].
References
[1] St Andre M, et, al. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skelet Muscle. 2017 Nov 9;7(1):25. DOI:10.1186/s13395-017-0141-y
Domagrozumab Preparation Products And Raw materials
Raw materials
Preparation Products
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