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Domagrozumab

Product Name
Domagrozumab
CAS No.
1629605-31-7
Chemical Name
Domagrozumab
Synonyms
Domagrozumab;Domagrozumab (anti-GDF8);Research Grade Domagrozumab;Research Grade Domagrozumab(DHA30603)
CBNumber
CB68080985
Formula Weight
0
MOL File
Mol file
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Domagrozumab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Domagrozumab Chemical Properties,Usage,Production

Uses

Domagrozumab is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD)[1].

in vivo

Domagrozumab (PF-06252616; 10 and 30 mg/kg; i.v.) increases myostatin levels in a dose-dependent manner and induces skeletal muscle hypertrophy in cynomolgus monkeys[1].

References

[1] St Andre M, et, al. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys. Skelet Muscle. 2017 Nov 9;7(1):25. DOI:10.1186/s13395-017-0141-y

Domagrozumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Domagrozumab Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
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QQ:3008007432
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China
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71826
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Guangzhou Hongyuan Chemical Co.,Ltd
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15817493340
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China
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Wuhan Chemstan Biotechnology Co., Ltd.
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Biolab Reagents
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products@biolabreagent.com
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China
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Wuhan Jingkangen Biomedical Technology Co., Ltd
Tel
13720134139 086-15871494362 13720134139
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orders@jknbiochem.com
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China
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6762
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Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
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China
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Changsha Fuzhen Biotechnology Co.,LTD
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Olix (Shanghai) Pharmaceutical Technology Co., Ltd
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Wanxin Biotechnology (Jiaxing) Co., LTD
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Atagenix Laboratories
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027-87008169 17762441161
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1629605-31-7, DomagrozumabRelated Search:


  • Domagrozumab
  • Research Grade Domagrozumab(DHA30603)
  • Research Grade Domagrozumab
  • Domagrozumab (anti-GDF8)
  • 1629605-31-7