(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
- Product Name
- (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
- CAS No.
- 7101-51-1
- Chemical Name
- (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
- Synonyms
- DOPA-METHYLESTER;L-DOPA Methyl Ester;levodopa methyl ester;Methyl 3-hydroxy-L-tyrosinate;3-Hydroxy-L-Tyrosine methyl ester;L-Tyrosine, 3-hydroxy-, Methyl ester;(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate;methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate;(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER;(S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride
- CBNumber
- CB6811125
- Molecular Formula
- C10H13NO4
- Formula Weight
- 211.21
- MOL File
- 7101-51-1.mol
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Property
- Boiling point:
- 350.89°C (rough estimate)
- Density
- 1.2545 (rough estimate)
- refractive index
- 1.5150 (estimate)
- storage temp.
- 2-8°C
- form
- solid
- pka
- 9.67±0.20(Predicted)
- color
- White
Safety
- HS Code
- 2922500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
N-Bromosuccinimide Price
- Product number
- CCH0004417
- Product name
- (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.06
- Updated
- 2021/12/16
- Product number
- OR955473
- Product name
- 3-Hydroxy-L-tyrosinemethylester
- Purity
- 96%
- Packaging
- 1g
- Price
- $508
- Updated
- 2021/12/16
- Product number
- OR955473
- Product name
- 3-Hydroxy-L-tyrosinemethylester
- Purity
- 96%
- Packaging
- 5g
- Price
- $1595
- Updated
- 2021/12/16
- Product number
- CM283194
- Product name
- (S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate
- Purity
- 95%
- Packaging
- 5g
- Price
- $746
- Updated
- 2021/12/16
- Product number
- CD21003806
- Product name
- (S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $790
- Updated
- 2021/12/16
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Chemical Properties,Usage,Production
Description
CHF-1301 was launched as an injection in Italy for the treatment of patients with Parkinson's disease, particularly those with complications in their clinical responses. CHF-1301 is the methyl ester of L-Dopa (levodopa), the immediate precursor of dopamine. Thus, this prodrug is more soluble in water at physiological pH, better absorbed and slowly transformed into levodopa in vivo; it consequently improves the duration of action and prevents the rapid fluctuations in response or involontary movements (dyskinesia) observed during chronic treatment with levodopa. In patients with a delayed effect of levodopa (on-phenomenon) or a severe resistance to L-Dopa (off-phenomenon), CHF- 1301 significantly improves the onset and the stability of the'response.
Originator
Chiesi Farmaceutici SpA (Italy)
Definition
ChEBI: Melevodopa is a tyrosine derivative.
brand name
Levomet
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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