3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE

Product Name: 3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE
CAS No.: 864754-21-2
Chemical Name: 3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE
Synonyms: 1-(3-PyridylMethyl)-1H-pyrazole-4-boronic acid pinacol ester;1-(Pyridin-3-ylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97%;1-(Pyridin-3-ylmethyl)-1H-pyrazole-4-boronic acid pinacol ester;3-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]methyl}pyridine;3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE;3-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine;Pyridine, 3-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]methyl]-;3-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine - [T25839]
CBNumber: CB6836681
Molecular Formula: C15H20BN3O2
Formula Weight: 285.15
MOL File: 864754-21-2.mol

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3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE Property

Melting point:: 102-106℃
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
Appearance: Off-white to yellow Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BML00215
Product name: 1-(Pyridin-3-ylmethyl)-1H-pyrazole-4-boronic acid pinacol ester
Purity: Aldrich
Packaging: 1g
Price: $427
Updated: 2025/07/31

Apolloscientific

Product number: OR361579
Product name: 1-(Pyridin-3-ylmethyl)-1H-pyrazole-4-boronic acid pinacol ester
Purity: 97%
Packaging: 250mg
Price: $66
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H60-1-35
Product name: 3-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-ylmethyl]-pyridine
Purity: 95%
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Synthonix

Product number: T25839
Product name: 3-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine
Purity: 97%
Packaging: 1g
Price: $190
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H60-1-35
Product name: 3-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-ylmethyl]-pyridine
Purity: 95%
Packaging: 1g
Price: $292
Updated: 2021/12/16

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3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE Chemical Properties,Usage,Production

Synthesis

69966-55-8

269410-08-4

864754-21-2

The general procedure for the synthesis of 1-(3-pyridinylmethyl)-1H-pyrazole-4-boronic acid pinacol ester from 3-bromomethylpyridine and 4-pyrazole boronic acid pinacol ester was as follows: 3-bromomethylpyridine (2.67 g, 15.5 mmol) and 4-pyrazole boronic acid pinacol ester (3.01 g, 15.5 mmol) were dissolved in N,N-dimethylformamide (DMF, 20 mL). ) in N,N-dimethylformamide (DMF, 20 mL), followed by addition of potassium carbonate (2.2 g, 16 mmol) to the reaction system. The reaction mixture was heated to 80 °C and the reaction was stirred at this temperature for 8 hours. After completion of the reaction, the mixture was poured into water (50 mL) and extracted with ethyl acetate (50 mL x 3), the organic phases were combined and washed with saturated brine (20 mL) and dried over anhydrous sodium sulfate. After the solvent was removed by concentration under reduced pressure, the residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate, v/v=1/1.5) to give 280 mg of the target product in the form of light yellow oil in 6.33% yield.

References

[1] Patent: CN106749268, 2017, A. Location in patent: Paragraph 0607; 0608

3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE Suppliers

China 38 India 2 United Kingdom 2 United States 6 Global 48

Alfa Aesar

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Email: tech@alfa.com
Country: India
ProdList: 6905
Advantage: 58

A.J Chemicals

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864754-21-2, 3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINERelated Search:

2,2,2-trifluoro-1-(pyridin-3-yl)ethanamine 1-(3,4-dimethoxy-2-nitrophenyl)ethanone 1-(3,5-dichloropyridin-4-yl)ethanone 1-(3,4-DICHLOROPHENYL)CYCLOBUTANECARBONITRILE 1-Methyl-4-pyrazole boronic acid pinacol ester 1-Methyl-1H-pyrazole-4-boronic acid 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester 3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE

3-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRAZOL-1-YLMETHYL]-PYRIDINE

3-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine

1-(3-PyridylMethyl)-1H-pyrazole-4-boronic acid pinacol ester

3-{[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]methyl}pyridine

1-(Pyridin-3-ylmethyl)-1H-pyrazole-4-boronic acid, pinacol ester 97%

Pyridine, 3-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]methyl]-

1-(Pyridin-3-ylmethyl)-<i>1H</i>-pyrazole-4-boronic acid pinacol ester

3-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine - [T25839]

864754-21-2