ChemicalBook > CAS DataBase List > 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
- Product Name
- 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
- CAS No.
- 189744-46-5
- Chemical Name
- 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
- Synonyms
- RO 10-5824;Ro 10-5824 dihydrochloride;2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine;4-Pyrimidinamine, 5-[(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl-;5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
- CBNumber
- CB6848552
- Molecular Formula
- C17H20N4
- Formula Weight
- 280.37
- MOL File
- 189744-46-5.mol
More
Less
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Property
- Boiling point:
- 456.7±45.0 °C(Predicted)
- Density
- 1.186±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- pka
- 6.49±0.40(Predicted)
More
Less
N-Bromosuccinimide Price
Tocris
- Product number
- 2329
- Product name
- Ro10-5824dihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $154
- Updated
- 2021/12/16
Tocris
- Product number
- 2329
- Product name
- Ro10-5824dihydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $628
- Updated
- 2021/12/16
TRC
- Product number
- R637503
- Product name
- Ro10-5824
- Packaging
- 25mg
- Price
- $210
- Updated
- 2021/12/16
Usbiological
- Product number
- 256473
- Product name
- Ro 10-5824 dihydrochloride
- Packaging
- 10mg
- Price
- $403
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0372993
- Product name
- 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.69
- Updated
- 2021/12/16
More
Less
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Chemical Properties,Usage,Production
Uses
The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. Ro 10-5824 Dihydrochloride is a selective dopamine D4?receptor partial agonist (2).
Definition
ChEBI: 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]-4-pyrimidinamine is an aminopyrimidine.
Biological Activity
Selective dopamine D 4 receptor partial agonist (EC 50 = 205 nM) that binds with high affinity (K i = 5.2 nM). Displays 250-fold selectivity over D 3 receptors and > 1000-fold selectivity over D 2 , D 1 and D 5 receptors.
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Suppliers
189744-46-5, 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDERelated Search:
4-Amino-5-aminomethyl-2-methylpyrimidine
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride