2,4,6-Tribromophenol Property

Melting point:

90-94 °C(lit.)

Boiling point:

282-290 °C746 mm Hg(lit.)

Density 

2.55

vapor density 

11.4 (vs air)

vapor pressure 

0.042-0.063Pa at 25℃

refractive index 

1.5580 (estimate)

Flash point:

282-290°C subl.

storage temp. 

2-8°C

solubility 

water: soluble0.007g/100ml at 25°C

pka

6.34±0.23(Predicted)

form 

Powder

color 

White to slightly brown

Water Solubility 

71 mg/L (15 ºC)

Merck 

14,9613

BRN 

776920

LogP

3.7-3.89 at 23.5-25℃

CAS DataBase Reference

118-79-6(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 2,4,6-tribromo-(118-79-6)

EPA Substance Registry System

2,4,6-Tribromophenol (118-79-6)

Safety

Hazard Codes 

Xi,N,Xn,T,F

Risk Statements 

36/37/38-51/53-20/22-39/23/24/25-23/24/25-11-63-43-45-50-36-67-40-22

Safety Statements 

26-36-61-37/39-45-36/37-16-7-24/25-23-53-37

RIDADR 

UN 1230 3/PG 2

WGK Germany 

2

RTECS 

SN1225000

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29081990

Hazardous Substances Data

118-79-6(Hazardous Substances Data)

Toxicity

guinea pig,LDLo,oral,3gm/kg (3000mg/kg),National Technical Information Service. Vol. OTS0522208,

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2,4,6-Tribromophenol Chemical Properties,Usage,Production

Chemical Properties

2,4,6-Tribromophenol is a white needle-shaped into prismatic crystals with has a penetrating bromine odor. In alcohol, chloroform, ether and caustic alkali solution, almost insoluble in water, sweet taste.

Uses

2,4,6-Tribromophenol is used as a certified reference standard for the determination of the analyte in multiple solid formulation drug products using gas chromatography coupled to tandem mass spectrometry.

Uses

2,4,6-Tribromophenol was used in analysis of nonylphenol, nonylphenol monoethoxylate and octylphenol in sediment, water and fish tissue.

Definition

ChEBI: 2,4,6-tribromophenol is a bromophenol that is phenol in which the hydrogens at positions 2, 4 and 6 have been replaced by bromines. It is commonly used as a fungicide and in the preparation of flame retardants. It has a role as an environmental contaminant, a fungicide and a marine metabolite.

Production Methods

2,4,6-Tribromophenol is produced by the controlled bromination of phenol.

General Description

Soft, long, white crystals with a bromine odor.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

2,4,6-Tribromophenol can react with oxidizing materials .

Hazard

By ingestion, inhalation, skin absorption. Strong skin irritant.

Fire Hazard

Data is not available for 2,4,6-Tribromophenol. 2,4,6-Tribromophenol is probably non-flammable.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the phenol from EtOH or pet ether. Dry it under vacuum over P2O5 at room temperature. [Beilstein 6 IV 1067.]